Báo cáo khoa học: a-Synuclein–synaptosomal membrane interactions Implications for fibrillogenesis pot

... 3855–3860. Ó FEBS 2004 Lipid-induced a-synuclein fibrillogenesis (Eur. J. Biochem. 271) 3189 a-Synuclein–synaptosomal membrane interactions Implications for fibrillogenesis Euijung Jo 1 , Audrey A. Darabie 1 , ... to distinguish subtle differences between m utant a nd WT a-synuclein interactions and to further elucidate potential roles for a-synuclein–lipid interactions...

Ngày tải lên: 30/03/2014, 15:20

... ex- amined and a stem and a root word-form found for it. For word-forms associated with multiple POS categories, the stem and root of a word-form were listed once for each POS category because the ... Frequency by POS Category Table 6 presents word-form counts for differ- ent suffix evidence values for the WebDuniya cor- pus. Since the real stems for the word-forms were not known,...

Ngày tải lên: 22/02/2014, 02:20

... perfor- mance with TFM, using the best parameter com- binations for each corpus making relatively few modifications: the left side of Figure 2 shows a rapid performance increase, particularly for ... athens contain potentially valuable informa- tion, but this is lost in a statistical analysis based purely on the content of each document, irrespec- tive of its temporal context. This informa...

Ngày tải lên: 08/03/2014, 04:22

... rule for type-raising (see e.g. Dowty 1988) can cause difficulties for the parsing scheme advocated here (Hepple 1987) and is therefore assumed to apply in the lexicon. So a proper name, for ... predicate (VP henceforth). Suppose also that the primary operations of the grammar are putting constituents together. Could the minimal parser for such a grammar account for the minimal...

Ngày tải lên: 17/03/2014, 09:20

... labelled classes. For the experiment, the trigram-based Tree Tag- ger was used to map tokens directly to the depen- dency classes (see for a similar approach (Srini- vas et al., 1996)). Performance was ... also given for the percentage of sentences getting a completely correct parse. 1 NEGRA distinguishes 33 grammatical roles. 2 Better performance is achieved when only the category info...

Ngày tải lên: 17/03/2014, 22:20

... INFORMATION The formalism of PATR offers two possible means of representing lexical informa- tion. First of all, the information can be encod- ed in feature structures directly. Except for ... be defined. For example, the lexical entry for frog would be FROG:<>==NOUN, where the noun-specific information is inherited from NOUN. This third approach forms the base for our...

Ngày tải lên: 18/03/2014, 02:20

... importance of a defined RNA structure was first elaborated for tRNAs, for which several conformers coexist in vitro. Only one of these conformers (the biologically func- tional structure) can be ... sites for double- stranded RNA and ATP overlap, resulting in coupled binding of both molecules. Simultaneous binding forces the RNA into a bent conformation that is incompatible with duplex fo...

Ngày tải lên: 14/02/2014, 19:20

... CP, Li H & Chen YJ (2008) A multiplexed quantitative strategy for membrane proteomics: opportunities for mining therapeutic targets for autosomal dominant polycystic kidney disease. Mol Cell Proteomics ... gel-assisted digestion and iTRAQ labeling MS is a poten- tial approach for uncovering and comparing membrane protein profiles of tissue samples that has the potential to iden...

Ngày tải lên: 16/02/2014, 15:20

... had an affinity, not for PE-containing membranes, but rather for anionic membranes contain- ing PG [16], and little information is available regard- ing the phospholipid and membrane binding of ... inhibitor to the membrane surface, and that the membrane protein interactions are then further stabil- ized by short-range specific interactions, resulting in the higher affinity for PS,...

Ngày tải lên: 19/02/2014, 05:20

... subunit responsible for membrane fusion and the surface (SU) subunit f or receptor binding. For a majority of the class I fusion proteins, a region in t he TM protein crucial for binding to and ... res idue obtained for the protonated and deuterium-exchanged peptide (for exchange experiments) or before and a fter introduction of Mn 2+ to d 25 -SDS micellar s olution (for relaxatio...

Ngày tải lên: 19/02/2014, 16:20