Báo cáo khoa học: Role of peroxidase inhibition by insulin in the bovine thyroid cell proliferation mechanism pdf

... responsible for the decrease of thyroid hormone biosynthesis in primary cultures in the presence of insulin. In addition, our data suggest that insulin stimulates cell division, in bovine thyroid cultures, ... significant increase in concentration of the peroxidase inhibitor by the action of insulin, during 48 h, in thyroid primary cultures with 0....

Ngày tải lên: 30/03/2014, 14:20

... demonstrates that the type and effect- iveness of inhibition of a cholinesterase by mercury strongly depend on the species. Therefore, the kinetic characterization of cholinesterase inhibition in the selected ... consequence of the cross- linking of two coordinating residues present at the surface of the protein. This aggregation depends on protein concentrat...

Ngày tải lên: 23/03/2014, 09:21

... target genes other than integrin a10, to clarify the role of AP-2e in chon- drocyte differentiation and in the development of osteoarthritis. Role of AP-2 in chondrocytic diseases A role for AP-2s ... helix–span–helix domain at the C-terminus shown in blue medi- ates dimerization and, together with the basic domain, (red) DNA-binding. ‘*’, amino acids that are iden...

Ngày tải lên: 16/02/2014, 09:20

... medium during the chase period allows the turnover of preaccu- mulated protein to be studied in the absence of further cellular uptake. In these studies, cell death was < 12% as measured by the ... demonstrated by receptor-blocking experiments. The rates of uptake of both the lipid and protein components are not matched by the rate of cel- lular metaboli...

Ngày tải lên: 19/02/2014, 02:20

... pro- teins with the exception of LsmDN88p. This suggests that each of the Lsm8p domains contributes to proper U6 binding, either directly or indirectly, by affecting the RNA-binding ability of the ... those with the C-terminal domain deleted is consistent with this (Figs 4 and 5). Hybrid proteins carrying the N-terminus of one protein and the Sm domain of the other...

Ngày tải lên: 07/03/2014, 02:20

... 17.6 Fig. 5. Insertion of stefins into DOPC and DOPG monolayers. (A) Kinetic traces of the insertion into DOPG lipid monolayers at initial pressure of 5 mNÆm )1 . The proteins were injected into the sub- phase ... the chip by three injections of 100 mm NaOH. Unspecific binding sites were blocked by one injection of 0.1 mgÆmL )1 bovine serum albumin. For the binding exp...

Ngày tải lên: 07/03/2014, 17:20

... the kinetic constants for hydrolysis and synthesis of penicillin G, ampicillin and cephalexin. Furthermore, insight into the nature of the transition state in the rate-determining steps of the ... 6-aminopenicillanic acid, caused by a higher affinity of the enzyme for 7-ADCA and complete suppression of hydrolysis of the acyl-enzyme upon binding of 7-ADCA. By co...

Ngày tải lên: 08/03/2014, 08:20

... involved reducing the starting material and the volume of the sucrose layers but maintaining the relative ratios of the sucrose layers. Infected Sf9 cells (about 6.6 · 10 7 ) were harvested by ... utilized in rat brain and infected Sf9 cells, and the role that occupancy of these sites has in the expression of functional Kv3.1s at the cell surface of Sf9 cel...

Ngày tải lên: 16/03/2014, 13:20

... human RXR (which is the ortholog of USP) have shown that an area on the surface of the ligand binding domain involving the C-terminus of a-helix 3, a-helix 4, and the N-terminus of a-helix 5 comprise ... The green fluorescent protein (GFP)-dUSP fusion protein was prepared in pIE1-4 by subcloning the GFP coding sequence for into the EcoRI ⁄ SmaI sites of the pIE1...

Ngày tải lên: 23/03/2014, 13:20

... mediator of lethal sepsis, triggering the production of proinflammatory cytokines and liver injury [13]. Therefore, the present study aimed to elucidate the role of KCs in the regulation of CYP isoform ... [22]. ROS indirectly reduced the activity of selected isoforms of CYP by inducing phosphorylation of the isoforms [23]. Activated KCs cause oxidative stress o...

Ngày tải lên: 14/02/2014, 18:20