Báo cáo khóa học: Glutamate signaling in peripheral tissues ppt

... Biomed. Sci. 6, 36–44. Ó FEBS 2003 Glutamate signaling in peripheral tissues (Eur. J. Biochem. 271)13 REVIEW ARTICLE Glutamate signaling in peripheral tissues Eiichi Hinoi, Takeshi Takarada, Taichi ... neurocrine system and an extracellular signal mediator in peripheral autocrine and/or paracrine tissues. In this review, the possible Glu signaling methods are outl...

Ngày tải lên: 30/03/2014, 13:20

... amalgamating or splitting axioms while leaving overall content unchanged (thus ensuring that exactly the same inferences are drawn by a reasoning engine); such rules are often used in reasoning algorithms. ... For instance, any set of SubClassOf axioms can be amalgamated into a single ‘metaconstraint’ (Horrocks, 1997) of the form   M, where  is the class containing all individuals in t...

Ngày tải lên: 20/02/2014, 04:20

... Computational Linguistics Managing Uncertainty in Semantic Tagging Silvie Cinkov ´ a and Martin Holub and Vincent Kr ´ ı ˇ z Charles University in Prague, Faculty of Mathematics and Physics Institute ... for develop- ing ontological and lexical resources in harmony. In 9th International Conference on Intelligent Text Processing and Computational Linguistics, pages 1–15. Berlin: Spring...

Ngày tải lên: 22/02/2014, 03:20

... community in the language-oriented fields has very little knowledge about using a computer to write interesting programs to gain a deeper understanding of the problems in their domain 2) ... their view of the computer being a giant adding machine with the more adequate view of being s general information processing device. We challenged their views thinking about the compute...

Ngày tải lên: 08/03/2014, 18:20

... men- tions being coreferent when making a final as- signment. This is exactly the kind of con- straint that integer linear programming (ILP) is ideal for, but, surprisingly, previous work applying ILP ... at training time we created data for all mention pairs. 2.2 Integer Linear Programming to Enforce Transitivity Because of the ad-hoc manner in which transitiv- ity is enforced in our base...

Ngày tải lên: 23/03/2014, 17:20

... information to be used both in interpretation and in generation. Our current and anticipated research in- cludes: refining and implementing our algorithms (including developing an inference mechanism ... both in interpretation and generation. 1 Introduction In this paper we present algorithms for the interpretation and generation of a certain kind of conversational implicatur...

Ngày tải lên: 31/03/2014, 06:20

... insulin signaling, and that it may repre- sent an interesting molecule with which to regulate liver insulin action. Experimental procedures Materials Porcine insulin, recombinant human insulin, ... effect on IR kinase and insulin signaling [10]. The interaction of Grb14 with PDK-1, an upstream kinase that activates Akt in response to insulin, appears to be required for insulin-induced me...

Ngày tải lên: 18/02/2014, 18:20

... to act as a defense mechanism in auto-immune diseases. Cross-linking of BCR of pre-mature B-cell lines, including the chicken DT40 cell line, with anti-immunoglobulin IgG induces apoptotic cell death. ... remained unchanged in the presence of PMA/ionomycin. Interestingly, in DT40, PMA/ionomycin treatment increased the caspase-8 mRNA level by 3 h (to approximately 160%) and this level re...

Ngày tải lên: 16/03/2014, 04:20

... metabolism and protein synthesis [43,44] resulting in polyamines such as putrescine, spermine and spermidine show a strong enhancing effect on neurite outgrowth both in vitro and in vivo [45–47]. Mitogen-activated ... GTPase-activating protein 2 [143]. Axonal injury results in a small up-regulation of rhoA, rac, cdc42, and a massive increase in TC10 [144]. Inhibition of rhoA in vi...

Ngày tải lên: 30/03/2014, 16:20

... occurrence of arginine residues at binding inter- faces. Indeed, in a database analysis of the contributions of individual amino acid residues to protein–protein inter- actions [20], arginine appears ... PSBD. In fact, the side-chains of lysine and arginine are significantly different, both in length and in the point (lysine) and delocalized (arginine) positive charge. Unlike lysine, a...

Ngày tải lên: 30/03/2014, 20:20