Báo cáo khóa học: The C-terminal t peptide of acetylcholinesterase forms an a helix that supports homomeric and heteromeric interactions potx

... putative organization of the C-terminal t peptide from AChE T . (A) Primary structure of the last 12 residues of the catalytic domain and of the t peptide. A comparison of the Torpedo and rat sequences ... introduced into rat AChE T subunits at various positions at the junction of the catalytic domain and the t peptide ()5to 6), in the m...

Ngày tải lên: 30/03/2014, 13:20

... and not an artefact of the MS analyses. These observations suggest that the MeOPN is synthesized in a nonmethylated form and is methyla- ted at a later point in time. Despite having a small CPS ... Sciences, National Research Council of Canada, Ottawa Ontario, Canada Campylobacter jejuni is one of the leading causes of human gastroenteritis and surpasses Salmonel...

Ngày tải lên: 16/03/2014, 13:20

... nonstoichiometric fructose branch at C-3 of galactose, and variable MeOPN groups at C-3 of both fructose branches at C-2 and C-3 of galactose (Fig. 1b). Most importantly, it was established that this structural ... [19] and a more sensitive enzymatic approach [20–22], we demonstrated that the method used to isolate CPS was an important factor that influ- enced the str...

Ngày tải lên: 30/03/2014, 20:20

... mentioned above, related to the equi- librium constant and thus to the enthalpy change due to the structural transition. The temperature dependence of the transition can be studied, and if the populations ... the T m values obtained by the two state interpretation of the CD data. These values of T m appear to fall near the minima of the / angle curves. Fo...

Ngày tải lên: 20/02/2014, 01:20

... subtask of syntax analysis, the di- chotomy manifests itself in the existence of learnt and handwritten grammars of natural languages. A great many formalisms have been advanced that fall into ... either of the two variants, but even the best of them cannot be said to interpret arbitrary input consistently in the same way that a human reader would. Because the...

Ngày tải lên: 17/03/2014, 04:20

... catalytic activity of PhyH is much greater than the activity sum of PhyH-DI and PhyH-DII and two times greater than that of PhyH- DII. This large variance cannot be ascribed to the function of ... fusion BPPs that showed greater catalytic constants towards InsP 6 than the original enzymes. It appears that the action of PhyH-DI is general, i.e. not limited to its in...

Ngày tải lên: 14/02/2014, 15:20

... kit (Stratagene, La Jolla, CA, USA): C153S-up, 5¢-TGCATC TTGCACTACCAACTCTCTTGCTCCCTTTGTC-3¢; and C153S-down, 5¢-TGACAAAGGGAG CAAGA GAGTTGG TAGTGCAAGATGC-3¢. The recombinant plasmids were introduced ... gluta- thionylation and thiol oxidation, and to examine the effect of these modifications on enzyme activity. The results demonstrate that Arabidopsis A 4 -GAPDH can undergo gl...

Ngày tải lên: 19/02/2014, 05:20

... c-andb proteobacteria. In contrast, the a proteobacteria, the Firmicutes, the Aquificales and the Thermotogales lack this inserted fragment. This suggests that Hfq from c-andb-proteobacteria evolved ... 2C, center-right). This suggests a conformational change at the interface between the subunits (Fig. 2C, bottom-right), that have been described as the strand b4ofchainB...

Ngày tải lên: 19/02/2014, 12:20

... that the introduction of rule-strength would amount to a mere implementational adaptation of no theoretical importance, we consider that it would impose a substantial restatement of the theory, ... entropy (uncertainty) manipulations (standard deviations are indicated into parentheses) in the immediate and delayed naming tasks. 2.1. Method Participants. Twenty Frenc...

Ngày tải lên: 20/02/2014, 19:20

... DNA replication at the elongation step, including the different interactions that coordinate leading and lagging strand synthesis. Although bacterial DNA replication has been stud- ied for decades, ... not alter its surface electro- static properties significantly. Therefore, the patch of an increased positive electrostatic potential appears to be the most distinct feature o...

Ngày tải lên: 05/03/2014, 23:20