Báo cáo khoa học: Oligomerization states of the association domain and the holoenyzme of Ca2+ ⁄CaM kinase II pptx

... state of the holoenzyme and that of the crystal structure of the association domain is unknown. Although the association domain is necessary and sufficient for formation of oligomeric CaMKII [18,19], ... Conclusion Determination of the crystal structure of the associ- ation domain of mouse CaMKIIa [10] was an import- ant step towards the ultimate goal...

Ngày tải lên: 30/03/2014, 11:20

... to the a and aA families. On the basis of the number of residues between the sec- ond and third cysteines and on the spacing between the third and fourth cysteines in the mature a-conotoxins, these ... describe the purification, amino acid sequence determination and cloning of the cDNA encoding two novel peptides, SrIA and SrIB, found in the venom of Con...

Ngày tải lên: 16/03/2014, 11:20

... Rapp, 1999) for the first and second models and propose a merging and disambiguation process for the two-stages transla- tion model. Therefore, context vectors of each term in source and target languages ... vec- tors SIM S→T and SIM T →S related to the first and second models respectively, are constructed for each pair of source term and target translation using the c...

Ngày tải lên: 20/02/2014, 16:20

... control. In the case of H-A-CM, the control is H-M-CM; in the case of H-A ⁄ Ang1-CM, the control is H-A-CM; in the case of H-A ⁄ IgG-CM, the control is H-A ⁄ Ang1-CM. Regulation of the blood–neural ... with an injury line and the distance of the injury line was measured. After 24 h, the quantification of the area of migration was performed (n = 4). The a...

Ngày tải lên: 23/03/2014, 07:20

... transmembrane domains (TM-A, TM-B) near their C-terminus and a GMN motif at the end of TM-A [11]. The short sequence connecting the two TM domains appears to be oriented towards the out- side of the bacterial ... expression and an enhanced concentration and stability of the protein at the plasma membrane, whereas the addition of Mg 2+ to the growing cells induc...

Ngày tải lên: 19/02/2014, 06:20

... composed of a hOrn and a haOrn moiety. Furthermore, a long-range 1 H– 13 C correlation was detected between the carbonyl carbon of the serine and the d-CH 2 of the hOrn, which constitutes the DKP. Therefore, ... characterization of these compounds is growing and may result in the synthesis of specific inhibitors based on the structure of the pathogen sideropho...

Ngày tải lên: 16/02/2014, 09:20

... lm) was then added to the mitochondria, and the CCCP-treated mito- chondria were incubated at 4 °C for 4 h. The mitochondrial suspension was then centrifuged at 12 000 g for 5 min, and the resulting ... minimal. Morphological evidence of the antiapoptotic effect of HSS As shown in Fig. 2A,B, the treatment of cells with 50 lm CCCP induced profound changes in the nuclear...

Ngày tải lên: 16/02/2014, 09:20

... vascu- lar tissue of cotyledons and mature leaves, whereas, in the flowers, the anthers, connectives and filaments and the base and tip of the stigmata were stained. Similar to BPM2, BPM3 and BPM5 promoter:GUS ... cotyledons and in the central cylinder of the root, but not in the lower parts of the hypocotyl (a). Rosette leaves were stained in the vascular...

Ngày tải lên: 18/02/2014, 06:20

... a molecular mass of 16 309.7 Da, but this matched none of the DNA-predicted proteins. MS ⁄ MS of these ions gave the C-terminal sequence of Fig. 5. These and all other peaks of that spectrum ... substitution; MS ⁄ MS will then show the substituent positions of dif- ferent isomers. A problem for MS ⁄ MS of either the peptides for the bottom-up approach or of the p...

Ngày tải lên: 18/02/2014, 16:20

... MS data on the components of all HPLC fractions indicate the presence of a variety of lipid, sugar and phosphate Fig. 1. The young of Macropus eugenii (A) climbing into the pouch and (B) attached ... (i.e. when the young has no immune system of its own), when there is a profound fall in the microbial flora of the pouch [6]. Neither eugenin nor other low molecular...

Ngày tải lên: 19/02/2014, 16:20