Báo cáo khoa học: Voltage- and Ca2+-activated potassium channels in Ca2+ store control Ca2+ release docx
Báo cáo khoa học: Voltage- and Ca2+-activated potassium channels in Ca2+ store control Ca2+ release docx
... openings of store
BK channels maintain the driving force for
Ca
2+
efflux with counter -in ux of K
+
. CICR,
Ca
2+
-induced Ca
2+
release. Right, Ca
2+
release declines due to closings of store ... lm
in the inner layer). Records before (A) and
3 min after beginning of quinidine applica-
tion (B), after application for 11 min (C) and
after washout for 100 min (D). (E) Two
states...
Báo cáo khoa học: Downregulation of protease-activated receptor-1 in human lung fibroblasts is specifically mediated by the prostaglandin E2 receptor EP2 through cAMP elevation and protein kinase A pot
... CTGF persistence in fibrotic gingiva: interac-
tions between cAMP and MAPK signaling pathways,
and prostaglandin E2-EP3 receptor mediated activation
of the c-JUN N-terminal kinase. J Biol Chem ... receptor-1 in
human lung fibroblasts is specifically mediated by the
prostaglandin E
2
receptor EP2 through cAMP elevation
and protein kinase A
Elena Sokolova
1
, Roland Hartig
2
and Georg...
Tài liệu Báo cáo khoa học: Structural and functional studies of the human phosphoribosyltransferase domain containing protein 1 docx
... HPRT
and hypoxanthine. (C) PRTFDC1 and
guanine. (D) HPRT and guanine.
Table 2. K
m
and V
max
values for Hx and G in the presence of 1 mM PRPP, determined using the DE-81 filter paper assay and ... differences in catalytic efficiency could be
explained by the difference in amino acid residues
involved in catalysis between PRTFDC1 and HPRT.
In the structure, residues inter...
Tài liệu Báo cáo khoa học: Pathways and products for the metabolism of vitamin D3 by cytochrome P450scc docx
... immunoregulatory and endocrine effects, and
is also a potent antiproliferative and differentiation-
inducing agent in different cell types, including epider-
mal keratinocytes [7–10]. To determine whether ... 20-hydroxyvitamin D3 and
20,23-dihydroxyvitamin D3 by P450scc
Incubation of 20-hydroxyvitamin D3 in cyclodextrin
with P450scc resulted in the formation of 20,23-di-
hydroxy...
Báo cáo khoa học: Separation and characterization of caveolae subclasses in the plasma membrane of primary adipocytes; segregation of specific proteins and functions docx
... after
charring in perchloric acid, according to Fiske and Subar-
row [39] and modified as in Svennerholm and Vanier [40].
Protein determination
Protein was quantitated using the protein quantitation ... proteins were also detected in the high-density
caveolae. In response to insulin, the insulin receptor autophosphorylation
and the amount of insulin-regulated glucose transporte...
Báo cáo khoa học: "Cohesion and Collocation: Using Context Vectors in Text Segmentation" pptx
...
added up, and the cosine between the resulting win-
dow vectors is assigned to the gap between the win-
dows in the text. High values indicate lexical close-
ness. Troughs in the resulting similarity'curve ... adjacent windows (200 words each in
this experiment) move over the input text, and at
pre-determined intervals (every 10 words), the vec-
tors associated with the...
Báo cáo khoa học: FLIP and MAPK play crucial roles in the MLN51-mediated hyperproliferation of fibroblast-like synoviocytes in the pathogenesis of rheumatoid arthritis pdf
... characteristics in RA patho-
genesis [1]. FLSs play a key role in the development of
sustained in ammation and angiogenesis in arthritic
joints [2–4]. Several cytokines and RA factors existing
in the ... in less severe disease and reduces cytokine levels
in tissue in vivo [8].
In RA synovium, FLSs express both tumor necrosis
factor-a (TNF-a) and Fas receptors, and t...
Báo cáo khoa học: Upstream and intronic regulatory sequences interact in the activation of the glutamine synthetase promoter pot
... observed.
Fig. 2. Main activity and interactions of GS upstream and intron modules in FTO-2B hepatoma and C2/7 muscle cells. Main activities and interactions
(±95% confidence interval) were calculated ... the minimal promoter and minimized
first intron. Panels III and IV show activities of combinations of upstream enhancer and the entire upstream region, respectively, in conju...
Báo cáo khoa học: ERK and cell death: ERK1⁄2 in neuronal death Srinivasa Subramaniam1 and Klaus Unsicker2 pptx
... can initi-
ate a caspase cascade upon binding of ligands such as
Fas ligand, TNF-a or TNF-related apoptosis-inducing
ligand [3]. Although caspases play a crucial role in cell
death, increasing ... the striatal neurons
degenerate. In Alzheimer’s disease (AD) and Parkin-
son’s disease (PD), cholinergic neurons in the basal
forebrain and dopaminergic neurons in the nigro-stria-
tal s...
Tài liệu Báo cáo khoa học: "The Impact of Query Refinement in the Web People Search Task" docx
... clustering task, with over 15 research groups
submitting results in each campaign. Since the re-
lease of the first datasets, this task is becoming an
increasingly popular research topic among Infor-
mation ... the goal is to mine the
web for information about a person. In a typical
hiring process, for instance, candidates are eval-
uated not only according to their cv, but also ac-
cordin...