... of HBV treatment. Although interferon alfa-2b, lamivudine, and adefovir are all approved as initial HBV treatment, understanding the advantages and advantages of each agent is important in choosing ... ALT Levels For many years, ALT has been used as a standard surrogate for the activity of CHB. Thus, ALT level in combination with HBV DNA level and histological activity has been used as a ... positive HBsAg, but negative HBeAg in serum that is associated with active HBV replication, elevated transaminases, and hepatic inflammation. Pathologically, it is secondary to mutant viral infection...