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Báo cáo khoa học: A family of killer toxins Exploring the mechanism of ADP-ribosylating toxins pptx

Báo cáo khoa học: A novel 2D-based approach to the discovery of candidate substrates for the metalloendopeptidase meprin pot

Báo cáo khoa học: A novel 2D-based approach to the discovery of candidate substrates for the metalloendopeptidase meprin pot

... residues, vari-able oxidation of methionine and variable deamidation of asparagine and glutamine. Parent and fragment mass toler-ances were set to 1 Da. Up to two missed cleavages andhalf tryptic ... JD, Amanchy R, Kristiansen TZ,Jonnalagadda CK, Surendranath V, Niranjan V,Muthusamy B, Gandhi TK, Gronborg M et al. (2003)Development of human protein reference database asan initial platform ... PAGE-based protease proteomic approach in substrate find-ing. 2D IEF ⁄ SDS ⁄ PAGE-based image analyses of the second quadrant.Fig. S2. 2D IEF ⁄ SDS ⁄ PAGE-based image analyses of the third quadrant.Fig....
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Báo cáo khoa học: A novel retinol-binding protein in the retina of the swallowtail butterfly, Papilio xuthus docx

Báo cáo khoa học: A novel retinol-binding protein in the retina of the swallowtail butterfly, Papilio xuthus docx

... light adaptation of the eye. Light adaptation alsoinduced the decrease of all-trans isomer both in the distaland proximal portions of the retina. In contrast, the increase of 11-cis ligand was ... using an ATTO AE6905CImage Saver, and quantified withNIH IMAGEprogram. The gel was then stained with Coomassie Brilliant Blue, and the protein content was measured via the absorbance of the stained ... migrates distally uponlight adaptation.We next analyzed the isomer composition of the nativeligands of Papilio RBP extracted separately from the distaland the proximal portions of the retina...
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Báo cáo khoa học: A novel mass spectrometric approach to the analysis of hormonal peptides in extracts of mouse pancreatic islets ppt

Báo cáo khoa học: A novel mass spectrometric approach to the analysis of hormonal peptides in extracts of mouse pancreatic islets ppt

... ethanol, sonicatedand extracted overnight at +4 °C [23]. After centri-fugation, the pellet was discarded and a sample of the supernatant was withdrawn for radioimmunoassay of insulin and glucagon ... Both end-plate potentials of the iontrap were set at 1.5 V and the duration of the electronpulse was 100 ms.Data acquisition and handlingPrimary data analysis was performed on a workstationrunning ... A novel mass spectrometric approach to the analysis of hormonalpeptides in extracts of mouse pancreatic isletsMargareta Ramstro¨m1, Charlotte Hagman2, Youri O. Tsybin2, Karin E. Markides1,...
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Báo cáo khoa học: A novel splicing variant form suppresses the activity of full-length signal transducer and activator of transcription 5A pot

Báo cáo khoa học: A novel splicing variant form suppresses the activity of full-length signal transducer and activator of transcription 5A pot

... activator of transcription 5A Yoshihisa Watanabe1, Masaya Ikegawa2, Yoshihisa Naruse3and Masaki Tanaka11 Department of Cell Biology, Research Institute for Neurological Diseases and Geriatrics, ... suppresses the tran-scriptional activity of STAT 5A. DiscussionWe isolated a novel STAT 5A splicing variant from the mouse brainstem. The STAT 5A_ DE18 variantlacked the transactivation domain and a tyrosineresidue. ... Lane 9: mammarygland. Lane 10: adrenal gland. Lane 11: N 2a cell line. Lane 12: STAT 5A_ FL cDNA. Lane 13: STAT 5A_ DE18 cDNA. A novel variant form suppresses full-length STAT 5A Y. Watanabe et al.6314...
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Báo cáo khoa học: Tec family kinases: Itk signaling and the development of NKT ab and cd T cells potx

Báo cáo khoa học: Tec family kinases: Itk signaling and the development of NKT ab and cd T cells potx

... given the more recent studies, a re-examination of the role of Ras in the development of these cells seems to be war-ranted. With regards to transcriptional targets of the Itk pathway, although the ... factors nuclear factor for activatedT cells (NFAT), nuclear factor kappa-light chainenhancer of activated B cells (NFjB) and activatorprotein-1 [4]. A number of studies have examined the Keywordsdevelopment; ... [53]. Because Itk may act as anamplifier in the TCR signaling, Itk deficiency may affect the SLP-76 signaling complex and dampen the TCR-mediated Ca2+influx and activation of PLCc1, weaken-ing...
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Báo cáo khoa học: A family of killer toxins Exploring the mechanism of ADP-ribosylating toxins pptx

Báo cáo khoa học: A family of killer toxins Exploring the mechanism of ADP-ribosylating toxins pptx

... a manner similar to that of the catalytic glutamate of the ADPRT and this could be essential to the mech-anism and form part of the mechanism that has notyet been captured in a crystallographic ... M,Murata T, Nakayama K, Asakawa K, Ohara M,Komatsuzawa H & Sugai M (2001) Complete nucleotidesequence of a Staphylococcus aureus exfoliative toxin Bplasmid and identification of a novel ADP-ribosyltrans-ferase, ... endosomes, the low pH activates the trans-location function of the B domain heptamers and theytranslocate the catalytic A domains across the endo-somal membrane into the cytoplasm where they can actto...
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Tài liệu Báo cáo khoa học: TEC family kinases in health and disease – loss-of-function of BTK and ITK and the gain-of-function fusions ITK–SYK and BTK–SYK pptx

Tài liệu Báo cáo khoa học: TEC family kinases in health and disease – loss-of-function of BTK and ITK and the gain-of-function fusions ITK–SYK and BTK–SYK pptx

... or SYK themselves, is capable of transforming NIH-3T3 cells [70]. In addition, weand others have demonstrated that the activation andplasma membrane localization of the fusion constructare dependent ... F, Cazzola G, Consolini R, De Mattia D,Dell’Erba G et al. (2002) Clinical, immunological, andmolecular analysis in a large cohort of patients withX-linked agammaglobulinemia: an Italian multicenterstudy. ... Hussain1,2,*, Liang Yu1,3,*, Rani Faryal1,2, Dara K. Mohammad1, Abdalla J. Mohamed1,4and C. I. Edvard Smith11 Clinical Research Center, Department of Laboratory Medicine, Karolinska Institutet,...
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Tài liệu Báo cáo khoa học: A facile method for expression and purification of the Alzheimer’s disease-associated amyloid b-peptide pdf

Tài liệu Báo cáo khoa học: A facile method for expression and purification of the Alzheimer’s disease-associated amyloid b-peptide pdf

... 5¢-GTTCACCACCAGAAGCTGGTGTTCTTC GCTGAA GACGT GGGTTCT AACAAGGGTGCT-3¢;Abc, 5¢-CACAACGCCACCAACCATCAGACCGATGATAGCACCCTTGTTAGAACCCAC-3¢;Ab-start, 5¢-GCGTAGGGTCGACATATGGACGCTGAATTCCGTCACG-3¢;Abstop, ... 5¢-CCTGCCGAGCTCCTATTACACAACGCCACCAACCATCAG-3¢. The PCR solution was prepared in the buffer suppliedwith the enzyme, and contained Aba, Abb and Abcat40 nm each, and the start and stop primers Abstart ... Ab(1–40) and Ab(M1–40) are at least 97%pure. In the lanes containing Ab(1–42) and Ab(M1–42), there were prominent bands at approximately4 kDa and faint bands at approximately 14 kDa. The band at approximately...
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Tài liệu Báo cáo khoa học: A knowledge-based potential function predicts the specificity and relative binding energy of RNA-binding proteins ppt

Tài liệu Báo cáo khoa học: A knowledge-based potential function predicts the specificity and relative binding energy of RNA-binding proteins ppt

... the performance of the potential will only increase with the size of the structural database and as terms areadded to the model to account for protein and RNAintra-molecular interactions that are ... Given the relativesparsity of the structural database, we investigatedwhether a reduced-atom representation would not leadto improved performance in the protein–RNA case. The all-atom potential ... to less favorable statistics(fewer structures of protein–RNA complexes). Weanticipate that the increasing availability of protein–RNA structures, together with the availability of dataon specificity,...
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Báo cáo khoa học: A study on genomic distribution and sequence features of human long inverted repeats reveals species-specific intronic inverted repeats pptx

Báo cáo khoa học: A study on genomic distribution and sequence features of human long inverted repeats reveals species-specific intronic inverted repeats pptx

... [46]. The appear-ance of the LIRs probably provides humans with anevolutionary advantage and contributes to the specia-tion of primates.Experimental proceduresIdentification of LIRs The human ... termed arms) that are approximately complemen-tary to each other. Generally, there is a spacer between the arms, and the full structure of an inverted repeatcan form a stem-loop or palindrome. The ... repeats areessential for the initiation of DNA replication in plas-mids, bacteria, eukaryotic viruses and mammalian cells[24]. The inverted repeats in introns are able to affect the alternative...
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Từ khóa: báo cáo khoa học mẫubáo cáo khoa học y họcbáo cáo khoa học sinh họcbáo cáo khoa học nông nghiệpbáo cáo khoa học lâm nghiệpBáo cáo quy trình mua hàng CT CP Công Nghệ NPVNghiên cứu sự hình thành lớp bảo vệ và khả năng chống ăn mòn của thép bền thời tiết trong điều kiện khí hậu nhiệt đới việt namNghiên cứu tổ hợp chất chỉ điểm sinh học vWF, VCAM 1, MCP 1, d dimer trong chẩn đoán và tiên lượng nhồi máu não cấpNghiên cứu vật liệu biến hóa (metamaterials) hấp thụ sóng điện tử ở vùng tần số THzGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWANNGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWAN SLIDEQuản lý hoạt động học tập của học sinh theo hướng phát triển kỹ năng học tập hợp tác tại các trường phổ thông dân tộc bán trú huyện ba chẽ, tỉnh quảng ninhPhát triển du lịch bền vững trên cơ sở bảo vệ môi trường tự nhiên vịnh hạ longThiết kế và chế tạo mô hình biến tần (inverter) cho máy điều hòa không khíSở hữu ruộng đất và kinh tế nông nghiệp châu ôn (lạng sơn) nửa đầu thế kỷ XIXKiểm sát việc giải quyết tố giác, tin báo về tội phạm và kiến nghị khởi tố theo pháp luật tố tụng hình sự Việt Nam từ thực tiễn tỉnh Bình Định (Luận văn thạc sĩ)Quản lý nợ xấu tại Agribank chi nhánh huyện Phù Yên, tỉnh Sơn La (Luận văn thạc sĩ)Giáo án Sinh học 11 bài 15: Tiêu hóa ở động vậtchuong 1 tong quan quan tri rui roGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtChiến lược marketing tại ngân hàng Agribank chi nhánh Sài Gòn từ 2013-2015TÁI CHẾ NHỰA VÀ QUẢN LÝ CHẤT THẢI Ở HOA KỲ