Báo cáo khoa học: Perturbation of membrane microdomains in G

Báo cáo khoa học: Perturbation of membrane microdomains in GLC4 multidrug-resistant lung cancer cells ) modiﬁcation of ABCC1 (MRP1) localization and functionality docx

... (200 7) 1470–1480 ª 2007 The Authors Journal compilation ª 2007 FEBS Perturbation of membrane microdomains in GLC4 multidrug-resistant lung cancer cells ) modiﬁcation of ABCC1 (MRP 1) localization and ... were obtained. MRP1, GM1 and caveolin-1 distribution within membrane fractions In order to determine the effect of MbCD on the integrity of...

Ngày tải lên : 30/03/2014, 09:20

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Tài liệu Báo cáo khoa học: What makes biochemical networks tick? A graphical tool for the identiﬁcation of oscillophores ppt

... [22], we linearize the system of Eqn ( 3) in the vicinity of the steady state. We do this to investigate the stability of this state. In this way we obtain the in uence a small change in the concentration ... cycles in such a combination do not touch each other). The value (the sign) of a cycle is the product of the values (the signs) of its steps. The sign o f the mag...

Ngày tải lên : 19/02/2014, 16:20

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Tài liệu Báo cáo khoa học: The calcium-induced switch in the troponin complex probed by ﬂuorescent mutants of troponin I doc

... interaction of the calcium binding troponin (troponin C) with bivalent cations and the inhibitory protein (troponin I). Biochem. J. 137, 145–154. 23. Hartree, E.F. (197 2) Determination of protein: a modiﬁcation ... R.S. (199 7) Mapping of a second actin-tropomyosin and a second troponin C binding sites within the C terminus of troponin I, and their importance in the C...

Ngày tải lên : 20/02/2014, 11:20

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Tài liệu Báo cáo khoa học: Perturbation of membranes by the amyloid b-peptide – a molecular dynamics study pptx

... 323 58.7 ± 1.1 ()7 .6 %) 59.5 ± 1.1 ()6 .3 %) E2 56.0 ± 0.8 ()5 .6 %) 55.4 ± 1.3 ()6 .6 %) P1 NA 62.5 ± 1.8 ()1 .6 %) 60.7 ± 0.9 ()4 .4 %) P2 57.1 ± 1.1 ()3 .7 %) 55.7 ± 0.8 ()6 .0 %) In the case of the OS ⁄ NS ... ()3 .2 %) B1 K28 300 46.8 ± 0.6 ()2 0 %) 55.2 ± 0.5 ()6 .0 %) B2 323 55.9 ± 1.3 ()1 2 %) 61.6 ± 0.8 ()3 .0 %) B...

Ngày tải lên : 18/02/2014, 08:20

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Tài liệu Báo cáo khoa học: Speciﬁc membrane binding of the carboxypeptidase Y inhibitor IC, a phosphatidylethanolamine-binding protein family member doc

... equivalent weight of PE, PS, PtdIns, PG (Sigma), PtdIns(3)P (Cay- man, Ann Arbor, MI), PtdIns(4)P (Cayman), PtdIns(5)P (Cayman), PtdIns(3,4)P 2 (Cayman), PtdIns(3,5)P 2 (Sigma), PtdIns(4,5)P 2 (Cayman), and ... liposomes of PS ⁄ PC (black), PtdIns(4,5)P 2 ⁄ PC (green), PtdIns(3,4,5)P 3 ⁄ PC (brown), PG ⁄ PC (lime), PtdIns(3,5)P 2 ⁄ PC (cyan), PtdIns(3)P ⁄ PC (yellow), PtdIns(4)P ⁄ PC (b...

Ngày tải lên : 19/02/2014, 05:20

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Báo cáo khoa học: Catalytically active membrane-distal phosphatase domain of receptor protein-tyrosine phosphatase a is required for Src activation doc

... activity of the RPTPa D2 domain is required for Src binding and activation It is well known that the membrane distal domains of RPTPs are involved in protein–protein interactions [16–18,20,28]. We investigated ... speciﬁcity of D1 in vitro [10,11]. In addition, the D2 domains were shown to be involved in intermolecular and intramolecular interactions, as well as in hom...

Ngày tải lên : 15/03/2014, 10:20

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Báo cáo khoa học: Oxidative stress is involved in the permeabilization of the inner membrane of brain mitochondria exposed to hypoxia/reoxygenation and low micromolar Ca2+ Lorenz Schild1 and Georg Reiser2 doc

... ± 1.5 pmol min )1 Æmg )1 of mitochondrial protein (n ¼ 5); after the addition of 5 mm glutamate and 5mm malate, 88.2 ± 5.7 pmol min )1 Æmg )1 of mitochondrial protein (n ¼ 5); and after subsequent ... nmolÆmg )1 of mitochondrial protein. The combination of 3.5 lm Ca 2+ and H ⁄ R led to the substantial decrease in GSH of 1.27 ± 0.15 nmolÆmg )1 of...

Ngày tải lên : 16/03/2014, 22:20

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Báo cáo khoa học: P-Glycoprotein is localized in intermediate-density membrane microdomains distinct from classical lipid rafts and caveolar domains potx

... partitioning of Pgp into intermediate- density microdomains. A B Fig. 1. Sucrose density gradient partitioning of P-glycoprotein (Pgp) and markers of classical lipid rafts. (A) CH R B30 cells ... colocalization of the two proteins by confocal ﬂuorescence microscopy. We ﬁrst examined the colocalization of GM 1 and caveolin-1 in CH R B30 cells. The individual staining p...

Ngày tải lên : 16/03/2014, 23:20

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Báo cáo khoa học: Perturbation of folding and reassociation of lactate dehydrogenase by proline and trimethylamine oxide potx

... of proline (< 1 M ), enhanced the rate and extent of reactivation of creatine kinase. In the limited instances in which wehave examined the effect of low proline concentrations (< 1 M ) ... m M dithiothreitol, pH 7. 6), or in buffer containing 3.4 M proline (B) or in buffer containing 1.6 M TMAO (C). Each line represents a single experiment. Fig. 6. Effect of...

Ngày tải lên : 23/03/2014, 15:21

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Báo cáo khoa học: The outer membrane component of the multidrug efﬂux pump from Pseudomonas aeruginosa may be a gated channel pptx

... on P. aeruginosa [16–18]. These efﬂux pumps of P. aeruginosa consist of two inner membrane- associated components, MexB (MexD, MexF, and MexY) and MexA (MexC, MexE, and MexX), and an outer membrane ... we examined the accessibility of a-chymotrypsin to tyrosine 185 and 196 of OprM existing in the cell. Hence, P. aeruginosa cells were suspended in NaCl/ P i and dig...

Ngày tải lên : 23/03/2014, 21:21

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