Báo cáo khoa học: Transducer of regulated CREB and late phase long-term synaptic potentiation pptx

... MINIREVIEW Transducer of regulated CREB and late phase long-term synaptic potentiation Hao Wu, Yang Zhou and Zhi-Qi Xiong Institute of Neuroscience and Key Laboratory of Neurobiology, Shanghai ... transcription. Transducers of regulated CREB activity (TORCs) With respect to the structure–function relationship of CREB activity, it was shown that deletion...

Ngày tải lên: 30/03/2014, 08:20

... of InsP 6 to PhyAsr (Table 1). Given the absence of structural changes as a function of ionic strength and ligand binding, the effect of ionic strength on catalytic activity is probably not of ... iso- morphous nature of the crystals allowed us to use the coor- dinates of 2B4P to calculate phases with the program sfall [17]. Statistics for the data collection and refinement...

Ngày tải lên: 18/02/2014, 18:20

... Sedla ´ c ˇ ek 3 and Jindr ˇ ich Has ˇ ek 1 1 Institute of Macromolecular Chemistry, 2 Institute of Organic Chemistry and Biochemistry and 3 Institute of Molecular Genetics, Academy of Sciences of the ... alternative positions of phenylalanine rings a re formed in concert with the alternative positions of S d and C c of Met46 and Met146 (from neighbouring protease di...

Ngày tải lên: 19/02/2014, 16:20

... action of EPA and DHA (Eur. J. Biochem. 271) 4465 Modulation of cyclin D1 synthesis and hyperphosphorylation of Rb by n-3 and n-6 PUFAs Induction of cyclin D1 is one of the e arliest effects of mitogenic ... concentra- tions of cyclin D1, Rb and Egr-1, in order to determine how the incorporation of EPA and DHA modulate SMC proliferation. This article describes the di...

Ngày tải lên: 19/02/2014, 16:20

... to learn thou- sands of Chinese characters. The official agents in Taiwan and China, respectively, chose 5401 and 3755 characters as important basic characters in national standards. Consequently, ... e.g., “賣” and “讀” are pronounced as /mai4/ and /du2/, respectively. In contrast, the pro- nunciations of “匋”, “淘”, “陶”, and “啕 ” are /tao2/. Pronunciations of specifi...

Ngày tải lên: 19/02/2014, 19:20

... consisting of the CSN, the 26S pro- teasome and cullin-based Ub ligases. Permanent expression of a chimerical subunit (Flag-CSN2-Rpn6) consisting of the N-terminal 343 amino acids of CSN2 and of the ... role of the PCI domain of CSN2 for complex formation and consequences of permanently overex- pressed CSN2 for the stability of p53 and c-Jun. The CSN interacts direct...

Ngày tải lên: 20/02/2014, 01:20

... Institute of Science and Technology, Ishikawa, Japan; 2 Department of Bioscience, School of Science and Technology, Kwansei Gakuin University, Hyogo, Japan; 3 Department of Synthetic Chemistry and ... T m of lysozyme was 77.3 °C in the absence of additives. The addition of 100 m M polyamines and Arg slightly increased the T m of lysozyme by  1 °Cand0.5°C, respectively...

Ngày tải lên: 20/02/2014, 02:21

... Program of the Office of the Director of NIH and by AIDS FIRCA Grant TW01001. The contents of this publication do not necessarily reflect the views or policies of the Department of Health and Human ... Louis 3 , Terry D. Copeland 4 , Ivan Y. Torshin 5 , Robert W. Harrison 5 and Jo ´ zsef To¨ zse ´ r 1 1 Department of Biochemistry and Molecular Biology, Faculty of Medicine...

Ngày tải lên: 21/02/2014, 03:20

... studies of inactive and active Src, the SH2 and SH3 domains are believed to form a ‘regulatory apparatus’. Binding of the phos- phorylated C-terminus to the SH2 domain and ⁄ or binding of the ... ligands of the SH3 and SH2 domains, respectively, both intra- and inter- molecularly, and thereby disrupt the overall functions of Src kinase [3,18–21]. After PP2 application, p...

Ngày tải lên: 06/03/2014, 01:20

... ribosomes and unacylated tRNA and how pppGpp synthesis is stimulated. We have isolated a recombinant His-tagged SF by affinity-purification and by taking advantage of the natural ability of the protein ... that synthesizes (p)ppGpp. Production of this alarmone results in a down-regulation of stable RNA synthesis (rRNA and tRNA) and up-regulation of the synthesis of mRNAs e...

Ngày tải lên: 07/03/2014, 16:20