Báo cáo khoa học: The domains carrying the opposing activities in adenylyltransferase are separated by a central regulatory domain ppt
Báo cáo khoa học: The domains carrying the opposing activities in adenylyltransferase are separated by a central regulatory domain ppt
... 2877 The domains carrying the opposing activities in adenylyltransferase are separated by a central regulatory domain Paula Clancy1, Yibin Xu1,2, Wally C. van Heeswijk1,3, Subhash G. Vasudevan1,4and ... C-terminal domains in these types ofproteins [10]. Together, these observations suggestedthat the opposing activities of the two domains may be separated by a third central domain, and that completeAT ... by separate domains within adenylyltransferase. The N-terminal domain carries the deadenylylation activity, and the C-terminal domain carries the adenylyla-tion activity [Jaggi R, van Heeswijk...
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Báo cáo khoa học: Functional domains of the human epididymal protease inhibitor, eppin docx
... study are interesting becausethey indicate that both domains are capable of causingrespiratory uncoupling.These data suggest that eppin acts as an antibacte-rial agent capable of killing Gram-negative ... [32–34]. WAP domains in otherproteins, however, have been shown to have proteaseinhibitory activity. For example, the C-terminal domain of avian WAP domain and Kunitz domain- containing protein exhibits ... resides in the Kunitz domain with the WAP domain having no inhibitory activity against the proteases tested. This observation correlateswith the finding that the amino-terminal WAP domain of SLPI...
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Báo cáo khoa học: Cold exposure and associated metabolic changes in adult tropical beetles exposed to fluctuating thermal regimes ppt
... Instead of consideringFAA only as a part of the osmo- and cryoprotectivearsenal, they should also be regarded as main actorsinvolved in the multiple regulatory pathways activatedduring cold acclimation ... d-pyrolline-5-carboxylate which, in turn, can be oxidized to Glu. Transamination gaverise to Ala and a- ketoglutarate. Such an increase in Ala contents is necessary to shuttle the amino groupderived ... investigated the impact ofcold exposure and associated metabolic changes in a year-round active beetle, A. diaperinus, introduced in temperate regions from the Ivory Coast (Africa). A. diaperinus was a...
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Báo cáo khoa học: "An Automatic Method for Summary Evaluation Using Multiple Evaluation Results by a Manual Method" pptx
... scores of the pooled summaries? Kazawa et al. calculated the score of a summary as a weighted linear sum of the manual scores. Applying regression analysis (Yasuda et al., 2003) is another method ... arbitrary summaries from the 10 summaries in a dataset were selected and ranked by Kazawa’s method. Then, Kazawa’s method was evaluated using “Precision,” which calculates the percentage of cases ... we compared the result by Yasuda’s method (Table 3) with that of Kazawa’s method (in Tables 1 and 2). Yasuda’s method could accurately estimate manual scores. In particular, the Gap values...
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Báo cáo khoa học: Respective roles of the catalytic domains and C-terminal tail peptides in the oligomerization and secretory trafficking of human acetylcholinesterase and butyrylcholinesterase potx
... study, the catalytic domains are indicated by capital letters ( A andB) and the C-terminal peptides by lower case letters (a and b), so that the wild-type enzymes are abbreviated asAa and Bb. The ... protein or alkaline phos-phatase allowed the formation of tetramers associatedwith an N-terminal fragment of ColQ [17]. However, the catalytic domains are also involved in quaternaryinteractions ... were similar for Aa and Ab, as well as for Ba and Bb, indicat-ing a predominant in uence of the catalytic domains. However, addition of a cysteine within the aromatic-rich segment of the t peptides...
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Báo cáo khoa học: Secondary transporters of the 2HCT family contain two homologous domains with inverted membrane topology and trans re-entrant loops docx
... the sequences in the database is about 60%.Hits between the N- and C-terminal halvesEach of the sequences in the domain database wasused as query in a blast search against all domains in the ... uses a database con-taining the N- and C-terminal halves of all the sequences in ST3 andinvolves blast searches of each sequence in the database against the wholedatabase. Unrelated families ... C-terminal halves and vice versa within the OPA family, the AAT family, the ST3 families and the DAACS1 family. In case of the AAT and DAACS1families, the percentage observed hits and the distribu-tion...
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Báo cáo khoa học: Solution structure of the bb¢ domains of human protein disulfide isomerase docx
... domains. In one struc-ture, the catalytic cysteines face each other; in the other, the catalytic residues of the a domain faceaway from the a domain. The crystal structures alsorevealed the presence ... cysteines in the C-terminal a domain increased the Kmto 30 lm, and loss of an additional cys-teine in the a domain resulted in an increase of the Kmto50 lm [25,27]. On the other hand, the ... pancre-atic microsomes [8], the highest of all ER residentproteins. PDI has four thioredoxin-like domains, a- b-b¢ -a , where the two a domains contain catalyticCGHC motifs, and the two b domains lack...
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Báo cáo khóa học: Structural characterization of the human Nogo-A functional domains Solution structure of Nogo-40, a Nogo-66 receptor antagonist enhancing injured spinal cord regeneration ppt
... expression of the Nogo -A fragments The Nogo -A cDNA (designated KIAA 0886) was obtainedfrom the Kazusa DNA Research Institute (Kazusa-Kamatari, K isarazu, Chiba, Japan). A DNA fragmentencoding a 182 ... doma in organization o f the hum an Nogo -A protein. (A) T he do main o rganizat ion of human Nogo -A s howing the N -terminal stretch region Nogo -A( 567–748) and the extracellular 66 amino a cid ... collapsing f unctions. The blackboxes indicate transmembrane domains. (B) The amino acid sequence of Nogo-40, a Nogo-66 receptor antagonist that has been demonstrated toenhance CNS neuronal...
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Báo cáo khoa học: Biochemical analysis of the human EVL domains in homologous recombination doc
... the barbed end and sides of actin filaments [15–18]. Theseactin-binding activities are conserved in the EVH2 domain [19,20]. On the other hand, the EVH1 domain binds to proteins containing the ... Pro-rich domains, also supporting the con-clusion that the EVH2 domain is the RAD51-binding domain in EVL. RAD51 and actin, which both bindATP, may share a common structural property that isrecognized ... [21–23]. The Pro-rich domain alsobinds to profilin and proteins containing the SH3 andWW domains [17,24–26]. These facts suggest that the EVH1, Pro-rich and EVH2 domains all have the potential to...
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Báo cáo khoa học: Identification of the heparin-binding domains of the interferon-induced protein kinase, PKR pptx
... according to the instructionsprovided with the kit:K29 9A: 5¢-GTTATTAAACGTGTTGCATATAATAACGAG-3¢; DM: 5¢-ACTTACGTTATTGCACGTGTTGCATATAATAACGAG-3¢; hep2: 5¢-CTGAAAAATGATGGAGAGCTCACAGAGAGTAAGGGAACTTTG-3¢. The ... amino-terminal heparin-binding domain (ATD) overlaps with the ATP-binding catalytic subdomain II and the carb-oxy-terminal heparin-binding domain (CTD) is locatedbetween the conserved kinase subdomains ... amino-terminal heparin-binding domain (ATD) of PKR.Thus, in contrast to the dsRNA-binding domain ofPKR, its heparin-binding domains are located in the carboxy-terminal half of the molecule. The amino-terminal...
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Từ khóa: Nghiên cứu sự biến đổi một số cytokin ở bệnh nhân xơ cứng bì hệ thốngBáo cáo quy trình mua hàng CT CP Công Nghệ NPVchuyên đề điện xoay chiều theo dạngNghiên cứu sự hình thành lớp bảo vệ và khả năng chống ăn mòn của thép bền thời tiết trong điều kiện khí hậu nhiệt đới việt namNghiên cứu vật liệu biến hóa (metamaterials) hấp thụ sóng điện tử ở vùng tần số THzđề thi thử THPTQG 2019 toán THPT chuyên thái bình lần 2 có lời giảiGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitQuản lý hoạt động học tập của học sinh theo hướng phát triển kỹ năng học tập hợp tác tại các trường phổ thông dân tộc bán trú huyện ba chẽ, tỉnh quảng ninhNghiên cứu về mô hình thống kê học sâu và ứng dụng trong nhận dạng chữ viết tay hạn chếNghiên cứu khả năng đo năng lượng điện bằng hệ thu thập dữ liệu 16 kênh DEWE 5000Định tội danh từ thực tiễn huyện Cần Giuộc, tỉnh Long An (Luận văn thạc sĩ)Sở hữu ruộng đất và kinh tế nông nghiệp châu ôn (lạng sơn) nửa đầu thế kỷ XIXTổ chức và hoạt động của Phòng Tư pháp từ thực tiễn tỉnh Phú Thọ (Luận văn thạc sĩ)BT Tieng anh 6 UNIT 2chuong 1 tong quan quan tri rui roGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtĐổi mới quản lý tài chính trong hoạt động khoa học xã hội trường hợp viện hàn lâm khoa học xã hội việt namHIỆU QUẢ CỦA MÔ HÌNH XỬ LÝ BÙN HOẠT TÍNH BẰNG KIỀM