Báo cáo khoa học: D-Amino acids in the brain: the biochemistry of brain serine racemase potx

... insulin receptor-interacting region (PIR) [6] and inhibits the tyrosine kinase activity of the IR [7]. On the basis of the crystal structure of the tyrosine kinase domain of the IR in complex with the PIR ⁄ BPS domain ... inhibitor in the substrate- binding groove of the kinase, whereas the SH2 domain interacts with phosphorylated tyrosine residues of the...

Ngày tải lên: 18/02/2014, 18:20

... not insulin- stimulated tyrosine phosphorylation of insulin receptor, exhibited insulin resistance. These findings suggest a new approach in the study of surgery- induced insulin resistance and indicate ... basis for insulin resistance. Elevated serine ⁄ threonine phosphorylation of IRS-1 and IRS-2 inhibits their binding to the juxtamem- brane region of the insulin receptor a...

Ngày tải lên: 07/03/2014, 16:20

... in which 90% of the transcripts are made at one brief phase of the cycle with the remaining transcripts made uniformly through the remainder of the cycle. Adding equal amounts of message to the ... to the samples at the beginning of RNA isolation. The use of actin and other constitutive, maintenance or housekeeping genes as normalizing standards is a time-honor...

Ngày tải lên: 30/03/2014, 04:20

... of the method of modular modeling is that the granularity of the submodels can easily be adjusted to the objective of the model and to the level of biological knowledge that is incorporated in ... function of the growth rate. In addi- tion, it allows the analysis of cellular processes in the case of mutations in the glucose uptake system or the PT...

Ngày tải lên: 18/02/2014, 13:20

... rare [19]. In the present study the interpre- tation of the CID spectra was greatly facilitated by the tendency of the protein to f ragment at amide bonds N-terminal to proline, giving intense y-type ... 5% of t he total cellular protein in human neutrophil granulocytes [6]. Histones are the major proteins in chromatin, where their function is toassist in DNA folding...

Ngày tải lên: 08/03/2014, 10:20

... determined in extracts of leaf and stem tissues. The moderate rate of COMT expression in the suspension cells is reminiscent of the correspondingly low COMT activity in cultured Petro- selinum ... under conditions of elicitation (Fig. 1) [17], and the induction of coumarin biosynthesis in these cell cultures provided the basis for extensive in vitro investiga- ti...

Ngày tải lên: 16/03/2014, 16:20

... recover the partial phrase structure, including the trace in Infl 2. In addition, we can recover the chain linking the did to its deep structure position in Infl (e-l), and also the 0-grid for the ... denote the linking of two C-Nodes, then we can define a Chain to be an ordered fist of C- Nodes, such that successive C-Nodes satisfy the link relation. In the...

Ngày tải lên: 18/03/2014, 02:20

... consisting of ThDP-sensing noncoding mRNA elements present in some mRNAs coding for enzymes involved in the thiamin biosynthetic pathways [17,18]. When plenty of ThDP is present, binding to the ... (ABC)-transporters, initiated with the binding of thiamin or one of its phosphate derivatives to the periplasmic protein component of the trans- porter [19]. Interestingly,...

Ngày tải lên: 29/03/2014, 23:20

... 1 The number contains the end two digits are digit 1 The number contains the end three digits are digit 1 The number contains the end four digits are digit 1 Answer : the number contains the ... know that the number contains the first four digits and the end four digits are digit 1 Step 1 : Find the number contains the end four digits are digit 1. Solution : The...

Ngày tải lên: 21/10/2013, 16:11

... successful metabolic engineering of freezing tolerance in plants should include such an analysis of the dynamics of metabolism to gain com- prehensive information about the effects of individual overexpression ... simulta- nous reduction in hexose concentration, particularly during the initial period of cold exposure. Using RNA interference-mediated inhibition of the d...

Ngày tải lên: 14/02/2014, 22:20