Báo cáo khoa học: Dynamics, stability and iron-binding activity of frataxin clinical mutants pdf
Báo cáo khoa học: Dynamics, stability and iron-binding activity of frataxin clinical mutants pdf
... frataxin mutants A. R. Correia et al.
3690 FEBS Journal 275 (2008) 3680–3690 ª 2008 The Authors Journal compilation ª 2008 FEBS
Dynamics, stability and iron-binding activity of frataxin
clinical mutants
Ana ... performed a comparative study
of the protein dynamics of frataxin variants carrying
mutations of clinical interest. We focused on how the
frataxin mut...
Báo cáo khoa học: Conformational stability and multistate unfolding of poly(A)-specific ribonuclease docx
... degradation
of the poly(A) tails of single-stranded mRNAs in a highly processive mode.
PARN participates in diverse and important intracellular processes by act-
ing as a regulator of mRNA stability and ... bind with the 3¢-poly(A) tail
and the 5¢-cap of the mRNA, and may be important
to the allosteric regulation of PARN [19–23].
In general, the structure and stability...
Tài liệu Báo cáo khoa học: Design, structure and biological activity of b-turn peptides of CD2 protein for inhibition of T-cell adhesion ppt
... bonds between NH of Thr5 and
CO of Arg2, as well as NH of Arg2 and CO of Thr5.
Structure of cyclic hexapeptides – cYT peptide. The
NMR data of the cYT peptide wer e indicative of its flexible
nature. ... structure of peptide cER
consists of two b-turns, located at the N- and C-termini. A
comparison of the b-turn structure of cER with the similar
region in the crysta...
Tài liệu Báo cáo khoa học: Molecular characterization and allergenic activity of Lyc e 2 (b-fructofuranosidase), a glycosylated allergen of tomato pdf
... specific 5¢ -and 3¢ primers selected on the basis of
the published sequences for tomato b-fructofuranosidase
(GenBank accession no. D11350 and S70040). Primers for
the short isoform of b-fructofuranosidase ... was calculated as percent of the
total amount of histamine determined after lysis of the
basophils by twofold freezing and thawing of the cells. A
histamine release of...
Tài liệu Báo cáo khoa học: Physicochemical characterization and biological activity of a glycoglycerolipid from Mycoplasma fermentans ppt
... of the horseshoe crab Limulus polyphemus,to
form a solid gel in the presence of minute amounts of
endotoxins. The comparison of LPS and MfGl-II in the
LAL assay shows, as expected, activity of ... water-binding capa-
city of lecithin headgroups [30]. Finally, MfGl-II exhibits a
main band at 1245 cm
)1
and further weak bands at 1220
and 1260 cm
)1
. Thus, the phosphate grou...
Báo cáo khoa học: Efficient and targeted delivery of siRNA in vivo pdf
... 4827
MINIREVIEW
Efficient and targeted delivery of siRNA in vivo
Min Suk Shim
1
and Young Jik Kwon
1,2,3
1 Department of Chemical Engineering and Materials Science, University of California, Irvine, ... with a strand of siRNA,
and the other siRNA strand was subsequently
annealed to the aptamer-conjugated strand. These
aptamer–siRNA conjugates were able to access HIV-
infected c...
Báo cáo khoa học: Improving thermostability and catalytic activity of pyranose 2-oxidase from Trametes multicolor by rational and semi-rational design pdf
... processing and evaluation were performed using the
origin 7.5 software.
Crystallization, data collection and refinement of
the E542K and L537G mutants
Crystals of the E542K, L537G and E542K ⁄ L537W
mutants ... mm
)1
Æcm
)1
). One unit of P2Ox activity was
defined as the amount of enzyme necessary for oxidation of
2 lmolÆmin
)1
of ABTS (which equals the consumption of...
Báo cáo khoa học: Physical properties and surface activity of surfactant-like membranes containing the cationic and hydrophobic peptide KL4 potx
... mimic some of the structural and functional proper-
ties of the native proteins and thus may offer a useful
basis for the design of agents for therapeutic interven-
tion [7]. Studies of different ... effect of the lipid composition on KL
4
struc-
ture, in the absence and presence of Ca
2+
, using CD
and (c) the role of the lipid composition and peptide
structure on sur...
Báo cáo khoa học: Thermodynamic stability and folding of proteins from hyperthermophilic organisms doc
... [15]. Analysis of a structural model of
AmFd suggests that a combination of additional sur-
face ion pairs, the zinc cofactor, and an efficiently
packed core govern the high stability of this protein
[36]. ... are
similar [55]. The stability profiles of TkRNase HII and
TtRNase HII are similar, although TkRNase HII
exhibits a higher temperature of maximum stability
and is...
Tài liệu Báo cáo khoa học: Helix mobility and recognition function of the rat thyroid transcription factor 1 homeodomain – hints from 15N-NMR relaxation studies pdf
... dis-
tribution of the energy between the overall tumbling
and the internal mobility, and is indicative of the
degree of internal restraint of each
15
N–
1
H vector
motion. In Fig. 4, most of the points ... graph of R
1
, R
2
and {
1
H}–
15
N NOE val-
ues along the sequence of the TTF1 HD at 11.7 T and
286 K.
Fig. S2. Plot of J(0.87x
N
)–J(0) correlation from
15
N
relax...
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