Báo cáo khoa học: Protein tyrosine phosphatases: functional inferences from mouse models and human diseases pot

... 2008 FEBS MINIREVIEW Protein tyrosine phosphatases: functional inferences from mouse models and human diseases Wiljan J. A. J. Hendriks 1 , Ari Elson 2 , Sheila Harroch 3 and Andrew W. Stoker 4 1 ... Phosphotyrosine-specific class I PTP-related phenotypes in mouse and human. Gene symbol Protein name PTP type a Mouse model Human ⁄ mouse ⁄ rat phenotype desc...

Ngày tải lên: 30/03/2014, 04:20

Ngày tải lên: 30/03/2014, 04:20

... (2004) Protein tyrosine phosphatases in the human genome. Cell 117, 699–711. 5 Barford D, Keller JC, Flint AJ & Tonks NK (1994) Purification and crystallization of the catalytic domain of human protein ... structures and inhibitor identification for PTPN5, PTPRR and PTPN7: a family of human MAPK-specific protein tyrosine phosphatases. Biochem J 395, 483–491. 14 Pedersen...

Ngày tải lên: 30/03/2014, 04:20

... coefficient, and the Dice coefficient (see also Jones & Fur- nas, 1987). For the computation of related terms and synonyms, Ruge (1995), Landauer and Dumais (1997), and Fung and McKeown ... ticles, pronouns, and particles) in an English and a German morphological lexicon (for details see Lezius, Rapp, & Wettler, 1998) and at word frequency lists derived from ou...

Ngày tải lên: 08/03/2014, 06:20

... a ‘gold standard’ human utterance from our dataset, which they must com- pare with utterances generated by models trained with and without active learning on a set of 20, 40, 100, and 362 utterances ... language understanding, dialogue management and text-to- speech synthesis (Rabiner, 1989; He and Young, 2005; Lef ` evre, 2006; Thomson and Young, 2010; Tokuda et al., 2000). S...

Ngày tải lên: 17/03/2014, 00:20

... leupeptin and pepstatin, twice in kinase buffer, and used for in vitro kinase assays. In vitro kinase assays Recombinant human protein kinase CK2 holoenzyme (0.5 U, corresponding to 1 ng; New England ... a (encoded by CKA1) and a¢ (encoded by CKA2), and two regulatory b subunits, b and b¢ in Saccharomyces cerevisiae (CKB1 and CKB2). The enzyme occurs in all possible combinatio...

Ngày tải lên: 18/02/2014, 16:20

... motifs with coat protein complex I (COPI), which functions in vesicular trafficking and retrieval of proteins from the Golgi apparatus to the ER [159,160]. For a newly synthesized protein to exit ... encoding plasma membrane and secreted proteins [202,203]. This complements the other UPR mechanisms aimed at relieving ER stress. Protein folding and oligomerization – ER and cytos...

Ngày tải lên: 07/03/2014, 06:20

... experiments, poli- tics (P), law (L), and economy (E). Two further categories are academic texts from the humani- ties (H) and from the field of science and technol- ogy (S). In the LPE corpus, ... genre only. On one hand, we have press texts (N), and more specifically NH, press texts from high quality broadsheets and magazines, on the other hand, fiction (F) and FL...

Ngày tải lên: 22/02/2014, 03:20

... to high-density lipo- proteins; (c) on the cell membrane of erythrocytes (and of other cells and cellular compartments); and (d) in gall stones and in human bile. Normal human blood serum contains ... seeds from rapeseed and soybean [30]. Clinical uses ChOx is a useful analytic tool for determining choles- terol in various samples: (a) total and esterified serum; (b) from lo...

Ngày tải lên: 07/03/2014, 00:20

... promote translation reuse and encourage authentic and idio- matic use in second language writing. We exploited and structured existing high- quality translations from the bilingual Si- norama ... full sentence, the system will search a sub- stantial and relevant corpus and return bilingual citations that are helpful to human translators and second language learners. 2 Al...

Ngày tải lên: 17/03/2014, 06:20