Báo cáo khoa học: Protein tyrosine phosphatases: sequences and beyond ppt

Ngày tải lên: 30/03/2014, 04:20

... motif; LMW-PTP, low molecular weight protein tyrosine phosphatase; N-SH2, N-terminal SH2 domain; PTP, protein tyrosine phosphatase; RPTP, receptor protein tyrosine phosphatase; YopH, Yersinia ... structures and inhibitor identification for PTPN5, PTPRR and PTPN7: a family of human MAPK-specific protein tyrosine phosphatases. Biochem J 395, 483–491. 14 Pedersen AK, Guo XL, Mo...

Ngày tải lên: 30/03/2014, 04:20

... 2008 FEBS MINIREVIEW Protein tyrosine phosphatases: functional inferences from mouse models and human diseases Wiljan J. A. J. Hendriks 1 , Ari Elson 2 , Sheila Harroch 3 and Andrew W. Stoker 4 1 ... & Bo ¨ hmer FD (2006) Protein- tyrosine phosphatases and cancer. Nat Rev Cancer 6, 307–320. 77 Mustelin T, Vang T & Bottini N (2005) Protein tyro- sine phosphatases and...

Ngày tải lên: 30/03/2014, 04:20

Ngày tải lên: 16/03/2014, 05:20

... band at approximately 263 nm and a negative band at approximately 240 nm, whereas anti- parallel G4 structures, such as basket and chair forms, show two positive bands at approximately 295 and 240 ... cisplatin mode to bind with G-rich sequences is vast; in principle, there is the possibility to bind within each guanine, to form intrastrand and interstrand bifunctional and monofun...

Ngày tải lên: 23/03/2014, 06:20

... ruminantium protein tyrosine phosphatase-like phytase; P-loop, phosphate-binding loop; PTP, protein tyrosine phosphatase; RPTPa, receptor protein tyrosine phosphatase alpha; Yop51, Yersinia protein tyrosine ... (PhyAsr I200 ; Protein Data Bank: 2PSZ), 300 mm (PhyAsr I300 ; Protein Data Bank: 3D1O), 400 mm (PhyAsr I400 ; Protein Data Bank: 3D1Q), and 500 mm (PhyAsr I500...

Ngày tải lên: 18/02/2014, 18:20

... without washing. NMR of His-cTCRf The protein was resuspended in 500 lLH 2 Oand50lL D 2 O, and the pH adjusted to 6 with dilute HCl. Standard 1D and 2D NOESY and DQF-COSY experiments were recorded ... absorption coefficients of 652 M )1 Æcm )1 for phospho- tyrosine [14] and 1427 M )1 Æcm )1 for tyrosine [15]. Gene cloning, protein expression, and purification of glutathione S...

Ngày tải lên: 08/03/2014, 02:20

... a (encoded by CKA1) and a¢ (encoded by CKA2), and two regulatory b subunits, b and b¢ in Saccharomyces cerevisiae (CKB1 and CKB2). The enzyme occurs in all possible combinations of a and b subunits ... biologically relevant consequences: (a) it increases Rio1 kinase activity and, conceivably, also controls interaction with other proteins (presumably during the G 1 phase); and (b)...

Ngày tải lên: 18/02/2014, 16:20

... (1996) Synthesis of protein farnesyltransferase and protein geranylger- anyltransferase inhibitors: Rapid access to chaetomellic acid A and its analogs. J. Org. Chem. 61, 6296–6301. 9. Pompliano, D.L., Rands, ... H. Chapman and Dr Javier Castillo ´ n for isolating the H. brasiliensis and P. argentatum WRP used in our experiments. Ms. Saima Kint and Dr Thomas McKeon kindly provid...

Ngày tải lên: 21/02/2014, 00:20

... 1 and 2 and, in more detail, in [31]. Several other methods have also been proposed recently that attempt to predict aggregation-prone or amyloidogenic regions in protein sequences. Clarke and ... recombinant proteins and for controlling the for- mation of bacterial inclusion bodies (IBs). Short description of prediction algorithms and available software Each method makes its own...

Ngày tải lên: 06/03/2014, 00:20