Báo cáo khoa học: The relative contribution of mannose salva

Báo cáo khoa học: The relative contribution of mannose salvage pathways to glycosylation in PMI-deﬁcient mouse embryonic ﬁbroblast cells pdf

... sufﬁcient mannose from other sources. We then determined the variation of amount of glycoprotein in cells. As shown in Fig. 5E, although the total amount of protein in cells decreased to 87% after ... glycoprotein dropped to nearly half the initial amount. On the other hand, the amount of glycoprotein in the medium did not differ substantially from the...

Ngày tải lên : 30/03/2014, 04:20

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Tài liệu Báo cáo khoa học: The crystal structure of coenzyme B12-dependent glycerol dehydratase in complex with cobalamin and propane-1,2-diol pptx

... protein staining. The ratio of the upper protein band to the lower one was estimated to be approximately 2 by densitometric scanning. Activity staining of the enzyme indicated that the upper ... cobalamins (2.9–5.1°) [9,10]. Figure 4C indicates the comparison of the position of the a-acetamide side chain of pyrrole ring A of the corrin ring in the glyce...

Ngày tải lên : 21/02/2014, 03:20

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Báo cáo khoa học: "The Beneﬁt of Stochastic PP Attachment to a Rule-Based Parser" doc

... Performance of the original parser on the test set. Besides adding the new constraint ‘PP attachment’ to the grammar, we also disabled several of the existing constraints that apply to preposi- tions, ... resolving the ambiguity in the category pattern ‘V+N+P+N’, i.e. predicting the PP attachment to either the verb or the ﬁrst noun. It is often assumed that...

Ngày tải lên : 17/03/2014, 04:20

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Báo cáo khoa học: The 3-ureidopropionase of Caenorhabditis elegans, an enzyme involved in pyrimidine degradation pptx

... this might indicate that its primary function does not lie in the degradation of pyrimidines. The localization in striated muscle cells might rather point to a role in providing b-amino acids for synthesis ... which, taking a monomer mass of 43.2 kDa into account, points to a dodecamer (Fig. 4). To support this ﬁnd- ing, the oligomeric state of the enzyme, the re...

Ngày tải lên : 23/03/2014, 03:20

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Báo cáo khoa học: "The clinical value of daily routine chest radiographs in a mixed medical–surgical intensive care unit is low"

... showed these two findings). However, even if we assume that all daily routine CXRs that showed one of these findings would have resulted in a change to therapy, the value of this diagnostic tool ... involved in drafting the manuscript. MG participated in analysis and interpretation of the data and in drafting the manuscript. PS, JS and MV contributed to the concept...

Ngày tải lên : 25/10/2012, 10:39

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Tài liệu Báo cáo khoa học: The central role of CDE/CHR promoter elements in the regulation of cell cycle-dependent gene transcription pdf

... conﬁrmed by Lin-54 binding to the CHR, cooperating with E2F4 binding to the CDE in EMSAs in vitro [86]. ChIP experiments on the Cdc2 gene also provided insights into the association of other cell ... proteins with the promoter. E2F4 binding during the cell cycle coincides with the binding of p107 or p130 [61,85]. Another E2F site distal to the E2F ⁄ CDE acts as...

Ngày tải lên : 16/02/2014, 09:20

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Tài liệu Báo cáo khoa học: The capsid protein of human immunodeﬁciency virus: intersubunit interactions during virus assembly doc

... H–D exchange in the assembled particle, relative to the free CA protein. Again, residues in helix 9 (and others) were involved in intersubunit interactions [33]. In the atomic structure of CTD, the dimerization interface ... of the precise residues and interactions involved in the NTD–CTD interface [46]. Most of these involve side chains from helix 8 of th...

Ngày tải lên : 18/02/2014, 06:20

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Tài liệu Báo cáo khoa học: The capsid protein of human immunodeﬁciency virus: designing inhibitors of capsid assembly ppt

... folding of both the CAI peptide and a-helix 9 of CTD during formation of the peptide– protein and protein–protein complexes. These NMR experiments also allowed the determina- tion of the CTD binding ... is important to note that some of the residues of CTD bound to CAI are also involved in binding to CAC1 and vice versa (see above); these data suggest that the...

Ngày tải lên : 18/02/2014, 06:20

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Tài liệu Báo cáo khoa học: The pro-form of BMP-2 interferes with BMP-2 signalling by competing with BMP-2 for IA receptor binding pptx

... unclear. In order to obtain an insight into the function of the pro-form (proBMP-2), the ability of proBMP-2 to induce alkaline phosphatase (AP), a marker enzyme for cells differentiating into os- teoblasts, ... speciﬁcally to the ECD of BMPR-IA. Furthermore, the results indicate that both proteins interact with the same epitope on the ECD because proBMP-2 bindin...

Ngày tải lên : 18/02/2014, 06:20

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Tài liệu Báo cáo khoa học: The crystal structure of human a-amino-b-carboxymuconatee-semialdehyde decarboxylase in complex with 1,3-dihydroxyacetonephosphate suggests a regulatory link between NAD synthesis and glycolysis ppt

... upregulation in the liver of streptozotocin-induced diabetic rats and the suppres- sion of such elevation following insulin injection [21,22], we decided to investigate the effect of N H CH 2 CH COOH NH 2 L-kynurenine CHO COOH COOH NH 2 Tryptophan α-amino-β-carboxymuconate-ε-semialdehyde ... homeostasis. Indeed, the enzyme stands at a branch point of the tryptophan to...

Ngày tải lên : 18/02/2014, 06:20

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