Báo cáo khoa học: Molecular and genetic characterization of osmosensing and signal transduction in the nematode Caenorhabditis elegans docx

... MINIREVIEW Molecular and genetic characterization of osmosensing and signal transduction in the nematode Caenorhabditis elegans Keith P. Choe and Kevin Strange Departments of Anesthesiology, ... of damaged proteins and activation of gpdh-1 expression. Green arrows and red lines indi- cate activation and inhibition, respectively. Osmosensing and si...

Ngày tải lên: 30/03/2014, 03:20

... including new topic candi- dates and words in the lexicon C, and the other set of nodes represents sentiment words, including new sentiment candidates and words in the lexicon B. For a pair of ... study the effect of different parameter settings. There are several parameters in the framework: the number of generated seeds r, the number of new candidates k 2...

Ngày tải lên: 19/02/2014, 19:20

... systems, including amyloid-beta protein, prion protein, transthyretin, a-synuclein, apolipoprotein C-II and insulin. To obtain information on the progression of the intermediate states, these were ... composed of the SH3 domain of PI3 kinase [42,43]. By mixing these labelled proteins in a 50 : 50 ratio and following the aggregation process, their data revealed that the f...

Ngày tải lên: 06/03/2014, 09:22

... Ca 2+ . Removing the proposed Ca 2+ -coordinating residues in positions 1 and 3 of the EF-hand motif significantly compromised the metal-binding capability of the engi- neered protein, indicating that the ... grafting approach to address this question. As shown in Fig. 1B, the distance between the two termini of the inserted Ca 2+ -binding sites in the model str...

Ngày tải lên: 07/03/2014, 00:20

... amount of the thing. The main modifications from the existing SURGE input structure are the introduction of the re/-set feature and the update of the usage of the possessor feature. For both of ... in the resulting sample: the selection of the unmarked realization option and the deter- mination of the default value of the definite featu...

Ngày tải lên: 08/03/2014, 06:20

... through the individual reactions and the concentration values of the respective reactants are being measured within the intact network operating in its cellular environment (i.e. either in the intact ... meta- bolites that mainly determine the integrity of the cell. The goodness of these simplified models was evaluated by using the solutions of the full mechan...

Ngày tải lên: 23/03/2014, 06:20

... BLEU scores as the objective. This avoids the heuristics of picking the updating reference and therefore gives a more principal way of setting the training objective. As another closely related ... training of each other, we train them in alternation. I.e., at each iteration, we first fix λ and update θ, then we re-tune λ given the new θ. Due to mismatch between t...

Ngày tải lên: 23/03/2014, 14:20

... edges, combining lev- els of nodes with the partitioning of gaps of non- projective edges into components. We derive a for- mal property of these signatures that links them to the constraint of well-nestedness, ... 1998)— there it is defined as the maximum over gap degrees of all subtrees of a dependency tree (the gap degree of a subtree is the number of contiguous i...

Ngày tải lên: 23/03/2014, 18:20

... including the stress response and food intake, are described. Expression of relaxin-3 in the brain Relaxin-3 neurons in the brain Examination of relaxin-3 mRNA expression by north- ern blotting ... expressed in the brain and testis. In rodent brain, ana- tomical studies have revealed its predominant expression in neurons of the nucleus incertus of the dorsal...

Ngày tải lên: 29/03/2014, 21:20

... monitored accumulation of the toxin at the interface of water and chloroform. The ratio of the aqueous phase concentration of the HlyA following partitioning with chloroform, c to the initial value, ... association of the protein in water, as indicated by light-scattering (Fig. 2) and gel filtration experiments. Furthermore, the complex of the HlyA with asia...

Ngày tải lên: 31/03/2014, 09:20