Báo cáo khoa học: Creating hybrid proteins by insertion of exogenous peptides into permissive sites of a class A b-lactamase doc
Báo cáo khoa học: Creating hybrid proteins by insertion of exogenous peptides into permissive sites of a class A b-lactamase doc
... three-dimensional
structure of TEM-1 is well characterized [7–9]. Like all
class A b-lactamases, TEM-1 folds into a structure
formed by an a ⁄ b-domain and an all -a- domain
(Fig. 1A) . At the junction ... structures of many naturally occur-
ring proteins reveal that they are composed of separate
domains arising from the insertion of a new stretch of
coding sequenc...
Tài liệu Báo cáo khoa học: Angiopoietin-like proteins: emerging targets for treatment of obesity and related metabolic diseases pptx
... beneficial.
Because ANGPTL2 promotes vascular inflammation
via the a5 b1 integrin ⁄ Rac1 ⁄ NF-jB pathway [15] and
vascular injury accompanied by inflammation is con-
sidered an early feature of arteriosclerosis ... Y, Akao M, Yasunaga K, Yamauchi T, Morisada
T, Ito Y, Urano T, Kimura Y, Kubota Y, Maekawa H
et al. (2005) Angiopoietin-related growth factor antago-
nizes obesity and insulin re...
Tài liệu Báo cáo khoa học: Minor capsid proteins of mouse polyomavirus are inducers of apoptosis when produced individually but are only moderate contributors to cell death during the late phase of viral infection ppt
... polyoma-
virus capsid proteins that serve as nuclear localization
signals. Trans Kans Acad Sci 96, 35–39.
5 Moreland RB & Garcea RL (1991) Characterization of
a nuclear localization sequence ... VP3–
EGFP, and to determine the role of the mitochondrial
pathway in apoptosis, cleavage of caspase 9 was investi-
gated. Figure 5D shows caspase 9 cleavage (resulting in
the appearance...
Tài liệu Báo cáo khoa học: Amino acid discrimination by arginyl-tRNA synthetases as revealed by an examination of natural specificity variants doc
... decrease the stability of the canavany-
lated species.
The role of tRNA as a cofactor for aminoacylation
in those aminoacyl-tRNA synthetases that require
tRNA for amino acid activation is well documented
[9], ... Preparation and colorimetric
analysis of l-canavanine. Anal Biochem 77, 147–151.
60 Ozinskas AJ & Rosenthal GA (1986) l-Canavanine syn-
thesis by zinc-mediated guanidin...
Tài liệu Báo cáo khoa học: Bone morphogenetic proteins in the early development of zebrafish pptx
... phosphorylation, are activated and bind to a
common mediator Smad (Co-Smad, Smad4).
The complexes move into the nucleus and act as
regulators of transcription. The activity of BMP is
regulated by the ... transcripts are found in the organizer
of gastrula embryos, later in the prechordal plate and
axial mesoderm (Fig. 2). By contrast, noggin2 tran-
scripts are detected at the end...
Tài liệu Báo cáo khoa học: DNA modification with cisplatin affects sequence-specific DNA binding of p53 and p73 proteins in a target site-dependent manner pptx
... major adduct of the anticancer
drug cisplatin. Nature 377, 649–652.
29 Zlatanova J, Yaneva J & Leuba SH (1998) Proteins that
specifically recognize cisplatin-damaged DNA: a clue to
anticancer ... Ichimiya S, Nakagawara A, Sakuma Y, Kimura S, Ikeda
T, Satoh M, Takahashi N, Sato N & Mori M (2000) p73:
structure and function. Pathol Int 50, 589–593.
23 Levrero M, De Laurenzi V, Cos...
Tài liệu Báo cáo khoa học: Integral membrane proteins in the mitochondrial outer membrane of Saccharomyces cerevisiae docx
... 745–751.
29 Osanai K, Takahashi K, Nakamura K, Takahashi M,
Ishigaki M, Sakuma T, Toga H, Suzuki T & Voelker
DR (2005) Expression and characterization of Rab38, a
new member of the Rab small G protein ... membrane, most of these mitochondrial pro-
teins behave as if they have a- helical transmembrane domains, rather than
b-barrels. These proteins are usually predicted to have...
Tài liệu Báo cáo khoa học: "Enhanced word decomposition by calibrating the decision threshold of probabilistic models and using a model ensemble" pdf
... boundaries as hidden
variables and include probabilities for let-
ter transitions within segments. The ad-
vantage of this model family is that it can
learn from small datasets and easily gen-
eralises ... terms of
training set size. We want to remind the reader that
our two algorithms are aimed at small datasets.
We randomly split each dataset into 10 subsets
where each subset was a...
Tài liệu Báo cáo khoa học: "Creating Robust Supervised Classifiers via Web-Scale N-gram Data" pdf
... bedrag-
gled 56-year-old [professor]. Also, in a particu-
lar domain, words may have a non-standard usage.
Systems trained on labeled data can learn the do-
main usage and leverage other regularities, ... evaluate the benefit of N-gram data on multi-
class classification problems. For each task, we
have some labeled data indicating the correct out-
put for each example. We evaluate with...
Tài liệu Báo cáo khoa học: "Creating a manually error-tagged and shallow-parsed learner corpus" pptx
... Lee and Seneff, 2008; Nagata et al., 2004;
Nagata et al., 2005; Nagata et al., 2006; Tetreault et
al., 2010b). This is one of the most active research
areas in natural language processing of learner ... corpus
Ryo Nagata
Konan University
8-9-1 Okamoto,
Kobe 658-0072 Japan
rnagata @ konan-u.ac.jp.
Edward Whittaker Vera Sheinman
The Japan Institute for
Educational Measurement Inc.
3-2-4 Kit...