Báo cáo khoa học: Oxygen-induced changes in hemoglobin expression in Drosophila docx
Báo cáo khóa học: Conformational changes of b-lactoglobulin in sodium bis(2-ethylhexyl) sulfosuccinate reverse micelles A fluorescence and CD study docx
... causing no changes in the far-UV CD spectra. So, the broad band centred at 270 nm obtained in bLG CD spectra upon encapsulation on AOT RM may arise from the changes in nature of the intra- and intermolecular ... changes in bLG may cause fluorescence quenching by mechanisms other than those involving close contact between Trp and water. A variety of chemical groups present in pr...
Ngày tải lên: 07/03/2014, 15:20
Báo cáo khoa học: Succinate dehydrogenase flavoprotein subunit expression in Saccharomyces cerevisiae – involvement of the mitochondrial FAD transporter, Flx1p ppt
... for FAD transport in Saccharomyces cerevi- siae. It has also been suggested that it has a role in maintaining the normal activity of mitochondrial FAD-binding enzymes, including lipoamide dehydrogenase ... By increasing the phenylsuccinate concentration, and therefore reducing the succinate transporter activity, we obtained a significant reduction in succinate respiration. Conversely, th...
Ngày tải lên: 23/03/2014, 07:20
Tài liệu Báo cáo khoa học: Accessibility changes within diphtheria toxin T domain when in the functional molten globule state, as determined using hydrogen⁄deuterium exchange measurements pdf
... chain corresponding to the catalytic domain (C domain); and the B chain corresponding to the translocation domain (T domain) and the receptor-binding domain. The C and T domains remain covalently linked ... protein secreted by Corynebacte- rium diphtheriae as a single polypeptide chain of 58 kDa [1]. During cell intoxication, diphtheria toxin is cleaved by furin into two fragments: the A chai...
Ngày tải lên: 16/02/2014, 09:20
Tài liệu Báo cáo khoa học: Adaptive changes in the expression of nuclear and mitochondrial encoded subunits of cytochrome c oxidase and the catalytic activity during hypoxia pptx
... (v/v) heat inactivated fetal bovine serum (Gibco) and 100 lgÆmL )1 penicillin/streptomycin. C2C12 cells were cultured as mono- layers in Falcon tissue culture dishes in a medium containing 10% (v/v) ... subunits in response to different physiological factors has not been investigated in detail. In a previous study we demonstrated that administration of inhibitors of heme biosynthesi...
Ngày tải lên: 20/02/2014, 23:20
Tài liệu Báo cáo khoa học: Analyzing changes of chromatin-bound replication proteins occurring in response to and after release from a hypoxic block of replicon initiation in T24 cells pptx
... staining is colocated with the BrdU staining and this again signifies that PCNA is only bound to chromatin portions where actively replicating DNA is present. Recruitment of proteins involved in ... contain- ing buffer, and in fraction 3, the chromatin fraction, all proteins remain that resist Triton extraction. We supposed that the latter fraction included, besides the common chromatin pro...
Ngày tải lên: 21/02/2014, 00:20
Báo cáo khoa học: Local changes in the catalytic site of mammalian histidine decarboxylase can affect its global conformation and stability pptx
... protein. These results provide insights for new alternatives to inhibit histamine production efficiently in vivo. Keywords: histidine decarboxylase; histamine; a-fluoro- methylhistidine; L -histidine ... suggesting several interaction points for the adduct within the catalytic center in addition to those established by the internal aldimine alone. From the shape of the a-FMH-treated protein...
Ngày tải lên: 08/03/2014, 08:20
Tài liệu Báo cáo khoa học: Hypothalamic malonyl-CoA and CPT1c in the treatment of obesity pptx
... peptide in hypo- thalamic malonyl-CoA while promoting an increase in proopiomelanocortin and cocaine and amphetamine regulated transcript. Taken together, these findings provide a compelling argument ... a minor role in brain energetics. Although most cells containing mitochon- dria maintain some ability to beta-oxidize long-chain fatty acids, adult neurons do not robustly oxidize long-c...
Ngày tải lên: 14/02/2014, 22:20
Tài liệu Báo cáo khoa học: Proteolytic processing regulates pathological accumulation in dentatorubral-pallidoluysian atrophy pdf
... aggregation: role in polygluta- mine-induced disease in SCA1 transgenic mice. Cell 95, 41–53. 6 Saudou F, Finkbeiner S, Devys D & Greenberg ME (1998) Huntingtin acts in the nucleus to induce apopto- sis ... ubiquitin and ATN1 antibodies, and also include nuclear inclusions in the DRPLA brains [2,26]. In the present study, the ATN1 antibody L55-2 labelled neuronal cytoplasmic and...
Ngày tải lên: 15/02/2014, 01:20
Tài liệu Báo cáo khoa học: Roles of heat shock factors in gametogenesis and development pptx
... coronal section at E14.5 in (F). (A) At E11.5, HSF2 is expressed in forebrain, midbrain and in hindbrain except for the midbrain, hindbrain midline. Surprisingly, the HSF2 expression pattern is ... birth in mouse brains [122,124]. No HSF4 DNA-binding activity was reported in the developing mouse brain so far. How- ever, Hsf4b is expressed in the adult mouse brain, including cere...
Ngày tải lên: 18/02/2014, 04:20
Tài liệu Báo cáo khoa học: A role of miR-27 in the regulation of adipogenesis ppt
... differentiation was initiated at 48 h post-transfection by maintaining the cells in culture medium containing 2% horse serum. Cells were fixed on day 4 of differentiation and stained with hematoxylin and eosin. ... the level of PPARc protein in committed prea- dipocytes under physiologically relevant conditions. Expression of miR-27 is elevated in obese mice In order to gain insights...
Ngày tải lên: 18/02/2014, 08:20