Báo cáo khoa học: Effects of the antioxidant PycnogenolÒ on cellular redox systems in U1285 human lung carcinoma cells docx

... Effects of the antioxidant Pycnogenol Ò on cellular redox systems in U1285 human lung carcinoma cells Valentina Gandin 1, *, Christina Nystro ¨ m 1 , Anna-Klara Rundlo ¨ f 1 , Kerstin Jo ¨ nsson-Videsa ¨ ter 2 , Frank ... antioxi- dant effects of Pycnogenol Ò on redox enzymes, with emphasis on the regulation of TrxR. Results Effects of Pycnogenol...

Ngày tải lên: 30/03/2014, 02:20

... any amino acid at this position would result in a change in the conformation of this loop. Changes in the conformation of the backbone at this point and changes in the orientation of other side ... positions, with the aim of determining whether any of the observed effects were a result of changes in the size and charge of the amino acid at these posit...

Ngày tải lên: 16/03/2014, 06:20

... substitution at position 16 of the D 24)37 GGN4 induced an a helical conformation in the previously flexible loop region in intact GGN4, thereby forming an entirely amphipathic a helix. In addition, the substituted ... peptide engineering. Out of the six gaegurins, GGN4 has the longest length and is the most abundant in the frog skin. Thus, the peptide is believed t...

Ngày tải lên: 31/03/2014, 09:20

... Mg 2+ binding. The introduction of a positive charged amino acid in muta- tion S795R in the second TM domain is likely to alter the conformation of the transmembrane domain. Thus, Fig. 9. Interaction ... increase in ALR1 expression and an enhanced concentration and stability of the protein at the plasma membrane, whereas the addition of Mg 2+ to the growing cell...

Ngày tải lên: 19/02/2014, 06:20

... each containing an extracellular ANP- binding domain (ECD), a transmembrane domain, and an intracellular domain consisting of an ATP-binding regulatory domain and a GCase catalytic domain [8]. ANP ... domains in the opposite direction without an appreciable change in the interdomain distance. (B) Schematic presentation of the movement of the juxta- membrane domains in resp...

Ngày tải lên: 07/03/2014, 03:20

... using the composition operation of FSTs. We formulate the parsing problem as associat- ing with each token of the input a label indicating whether that token belongs to one of a business listing ... on exploiting the ASR output be- yond the 1-best hypothesis. We demonstrate that by parsing word confusion networks, the accuracy of the query parser can be improved. We fu...

Ngày tải lên: 08/03/2014, 21:20

... nonproductive folding or aggregation. O’Donohue and Beaumont [12] demonstrated dual roles of the prosequence of thermo- lysin in enzyme inhibition and folding in vitro. This group further demonstrated that the ... starting from Leu1. Therefore, the requirement of Val at the N-terminus might be depen- dent on the conformation of each protease. It would be interesting to...

Ngày tải lên: 16/03/2014, 06:20

... resistance was felt, thereby indicating occlusion of the origin of the MCA in the Willis circle. The silk suture was tightened around the intraluminal filament to prevent bleeding. The wound was then sutured ... to involve the activa- tion of intracellular ERs. In fact, administration of the Fig. 3. FAAH and CB1 receptor content in the striatum of rats sub- je...

Ngày tải lên: 23/03/2014, 07:20

... resulting in a Trp449 fi Stop mutation. The predicted truncated protein lacks the C-terminal 121 amino acids, which include the putative carotene-bind- ing domain [37], making the accumulation of minor amounts ... Physical map of the pB21H integration at the homologous carB sequence by a single recombination event in the genome of strain SF1. The mutation in the c...

Ngày tải lên: 30/03/2014, 01:20

... cooperativity of unfolding is more pronounced in VsEndA. This effect indicates the formation of a more compact struc- ture through the strengthening of intramolecular inter- actions or the weakening of intramolecular ... N69Q may increase the flexibility of the 69–72 loop, possibly explaining the decreased bind- ing affinity and increased catalytic rate. In addition,...

Ngày tải lên: 16/03/2014, 06:20