Báo cáo khoa học: Phosphopantetheinyl transferase inhibition and secondary metabolism doc

... PPTase inhibition and secondary metabolism FEBS Journal 276 (2009) 7134–7145 ª 2009 The Authors Journal compilation ª 2009 FEBS 7145 Phosphopantetheinyl transferase inhibition and secondary metabolism Timothy ... transfer in primary and secondary PPTase inhibition and secondary metabolism T. L. Foley et al. 7144 FEBS Journal 276 (2009) 7134–7145 ª 2009 The Auth...

Ngày tải lên: 30/03/2014, 01:20

... a recognition pattern on the left-hand side, written as a regular expression, and an output description on the right-hand side. A named label serves as a handle to the rule. Regular expressions ... provides standard operations for constructing and manipulating TFSs; and (iv) an XTDL grammar interpreter. Currently, SProUT offers three online compo- nents: a tokenizer, a gazetteer...

Ngày tải lên: 20/02/2014, 16:20

... object usage and support verbs Pasi Tapanainen, Jussi Piitulainen and Timo J~irvinen* Research Unit for Multilingual Language Technology P.O. Box 4, FIN-00014 University of Helsinki, Finland http ... most frequent of such expressions, make amends and take precedence, appeared less than twenty times, and the expressions have temerity, go berserk and go ex-dividend were even les...

Ngày tải lên: 20/02/2014, 18:20

... ‘intrinsic’ and ‘extrinsic’. ‘Extrinsic’ factors include those that can be manipulated by experimental conditions, such as the presence and amount of phosphate and adenine nucleotides, pH and ionic ... are still unknown: the molecular identities of the uniporter and PTP are unknown, and the identities of the Na + ⁄ Ca 2+ exchanger and possi- bly the Ca 2+ ⁄ H + antiporter have o...

Ngày tải lên: 23/03/2014, 03:20

... Distance Pronominalisation and Global Focus Janet Hitzeman and Massimo Poesio CSTR and HCRC, University of Edinburgh 2 Buccleuch Place, Edinburgh EH8 9LW, Scotland {J. Hi t z eman, Mass imo. ... both the jeweller and the bangle. Indeed, the bangle could also be referred to with a pronoun: And it took him something like 120 hours of work. The fact that pronouns and def- in...

Ngày tải lên: 23/03/2014, 19:20

... language syntax and se- mantics. Initially, this research was for the larger part confined to the classical categorial calculi of Aj- dukiewicz [1935] and Bar-Hillel [1953], and, in partic- ... definition encompasses the important cases of commutativity and associa- tivity. On the other hand, well-known rules such as weakening and contraction can't be modelled by resource...

Ngày tải lên: 01/04/2014, 00:20

... the relaxation data, and N. Srinivasan and S. Yamunadevi for their help with modeling and analyzing the A. thaliana PS protein. References 1 Umbarger E & Brown B (1958) Isoleucine and valine metabolism ... based on docking and pharmacophore models. J Chem Inf Model 45, 1101–1108. 36 Sarkhel S & Desiraju GR (2004) N–H O, O–H O, and C–H O hydrogen bonds in protein–ligand c...

Ngày tải lên: 16/02/2014, 09:20

... 2-mercaptoethanol and dithiothreitol. For example, 1mm dithiothreitol caused 72% and 85% inhibition of BHLmL2 and BHAb, respectively, while 1 mm 2-mer- captoethanol caused 85% and 97% inhibition of BHLmL2 and ... to determine the type of inhibition and the K i using brassinin (0.10–0.40 mm) as a sub- strate in the presence of inhibitor (0.10, 0.20 and 0.40 mm). The kinetic...

Ngày tải lên: 18/02/2014, 14:20

... [9]), and closed (B, PDB entry 1UAE [11]), conformation. The thiol group of C115 is highlighted in green and the nitrogen atoms of R120 and K22 in blue. The open form of MurA is unliganded (A) and the ... cloacae MurA (left) and the K22V mutant protein (right). (A and B) Tryptic digest of wild-type MurA and the K22V mutant protein (no additions). (C and D) Wild-type E. cloacae...

Ngày tải lên: 19/02/2014, 13:20

... 14634–14641. 25 Sandoval IV & Bakke O (1994) Targeting of membrane proteins to endosomes and lysosomes. Trends Cell Biol 4, 292–297. Biology and chemistry of b-secretase (BACE-1) C. E. Hunt and A. ... 40, 10001–10006. 110 Andrau D, Dumanchin-Njock C, Ayral E, Vizzavona J, Farzan M, Boisbrun M, Fulcrand P, Hernandez JF, Martinez J, Lefranc-Jullien S et al. (2003) BACE1- and BACE2-e...

Ngày tải lên: 07/03/2014, 00:20