Báo cáo khoa học: Mutation of epidermal growth factor receptor is associated with MIG6 expression docx

Báo cáo khoa học: Mutation of epidermal growth factor receptor is associated with MIG6 expression docx

Báo cáo khoa học: Mutation of epidermal growth factor receptor is associated with MIG6 expression docx

... regulatory mechanism of MIG6 in relation to the EGFR mutation. The present study is the first to show the association of MIG6 expression with the EGFR mutation in cancer. MIG6 ⁄ RALT is known to be ... 5239–5251 ª 2009 The Authors Journal compilation ª 2009 FEBS 5251 Mutation of epidermal growth factor receptor is associated with MIG6 expression Take...
Ngày tải lên : 30/03/2014, 01:20
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Báo cáo khoa học: Folding of epidermal growth factor-like repeats from human tenascin studied through a sequence frame-shift approach pdf

Báo cáo khoa học: Folding of epidermal growth factor-like repeats from human tenascin studied through a sequence frame-shift approach pdf

... ecog- nized as misfolded by the protein disulfide isomerases is not known in detail yet. The structure of an e ntire protein disulfide isomerase is still lacking, but homology modeling of the peptide ... Esposito (University of Udine) f or assistance with NMR d ata acquisition, and t o Sotir Zahariev (ICGEB) for helpful suggestions. This work is part of F.Z. PhD thesis at ICGEB-...
Ngày tải lên : 23/03/2014, 13:20
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Báo cáo khoa học: Control of transforming growth factor b signal transduction by small GTPases pot

Báo cáo khoa học: Control of transforming growth factor b signal transduction by small GTPases pot

... N-cadherin expression. This process is associated with embryonic tissue movements and also with cancer cell invasive- ness and metastasis. The earliest event in TGFb- induced EMT is the activation of ... recycling of epidermal growth factor receptors. J Biol Chem 277, 49158–49166. 81 Matsuzaki T, Hanai S, Kishi H, Liu Z, Bao Y, Kikuchi A, Tsuchida K & Sugino H (2002)...
Ngày tải lên : 07/03/2014, 01:20
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Báo cáo khoa học: Activation of hepatocyte growth factor activator zymogen (pro-HGFA) by human kallikrein 1-related peptidases docx

Báo cáo khoa học: Activation of hepatocyte growth factor activator zymogen (pro-HGFA) by human kallikrein 1-related peptidases docx

... In addition, several growth factors require proteolysis to gain full biological activity. Hepatocyte growth factor ⁄ scatter factor (HGF ⁄ SF) is a multifunctional Keywords hepatocyte growth factor; HGF ... hepatocyte growth factor activator inhibitor; HAI-1KD-1, secreted form of hepatocyte growth factor activator inhibitor type 1 consisting of the first Kunitz domain;...
Ngày tải lên : 23/03/2014, 07:20
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Tài liệu Báo cáo khoa học: Upregulation of the a-secretase ADAM10 – risk or reason for hope? docx

Tài liệu Báo cáo khoa học: Upregulation of the a-secretase ADAM10 – risk or reason for hope? docx

... studies with a variety of ligands for nuclear receptors narrowed the receptors involved down to a nonpermissive retinoic acid receptor retinoid X receptor heterodimer [33]. Another approach is offered ... contrast, ADAM10 overexpression or activation in the brain might be beneficial for the treatment of neurodegenera- tive diseases, in particular AD: this progressive disor- der of...
Ngày tải lên : 16/02/2014, 09:20
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Tài liệu Báo cáo khoa học: ¨ Induction of Kruppel-like factor 4 by high-density lipoproteins promotes the expression of scavenger receptor class B type I pptx

Tài liệu Báo cáo khoa học: ¨ Induction of Kruppel-like factor 4 by high-density lipoproteins promotes the expression of scavenger receptor class B type I pptx

... activation of endothelial cells and macrophages, as well as the differentiation and proliferation of VSMCs. Overexpression of KLF4 induced expression of multiple anti-inflammatory and antithrombotic factors, ... and antithrombotic factors, whereas knockdown of KLF4 led to the enhancement of tumour necrosis factor a-induced vascular cell adhesion molecule-1 and tissue factor...
Ngày tải lên : 18/02/2014, 04:20
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Tài liệu Báo cáo khoa học: Selection of stably folded proteins by phage-display with proteolysis docx

Tài liệu Báo cáo khoa học: Selection of stably folded proteins by phage-display with proteolysis docx

... the fact that a lot of neutral mutations exist, which makes it difficult to find which mutation or combination of mutations is important for stability. To gain insights into this issue, Martin et ... limitation of the phage-display and proteolysis method is that the size of the library is relatively small, permitting simultaneous mutations only at about six positions for each li...
Ngày tải lên : 19/02/2014, 12:20
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Báo cáo khoa học: Activation of activating transcription factor 2 by p38 MAP kinase during apoptosis induced by human amylin in cultured pancreatic b-cells ppt

Báo cáo khoa học: Activation of activating transcription factor 2 by p38 MAP kinase during apoptosis induced by human amylin in cultured pancreatic b-cells ppt

... activation of the p38 kinase pathway in b-cells is consistent with the general role of the p38 kinase pathway in cellular regulation of antiproliferation and apoptosis. However, this pathway is only ... Liu JX, Saafi EL & Cooper GJS (1999) Induction of apoptosis by human amylin in RINm5F islet beta-cells is associated with enhanced expression of p53 and p21 (WAF1 ⁄...
Ngày tải lên : 07/03/2014, 12:20
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Báo cáo khoa học: Secretion of macrophage urokinase plasminogen activator is dependent on proteoglycans potx

Báo cáo khoa học: Secretion of macrophage urokinase plasminogen activator is dependent on proteoglycans potx

... MMPs, fibroblast growth factor and transforming growth factor b [26]. In atherosclerosis, lipid-rich macro- phages increase uPA and plasmin expression and the release of growth factors from the ... Kolset 5 1 Department of Veterinary Medical Chemistry, Swedish University of Agricultural Sciences, Uppsala, Sweden; 2 Department of Biochemistry, Institute of Medical Biology,...
Ngày tải lên : 08/03/2014, 08:20
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Báo cáo khoa học: Improvement of a monopartite ecdysone receptor gene switch and demonstration of its utility in regulation of transgene expression in plants pdf

Báo cáo khoa học: Improvement of a monopartite ecdysone receptor gene switch and demonstration of its utility in regulation of transgene expression in plants pdf

... such as antisense RNA, loss of function, gain of function, ectopic expression and overexpression cannot be eas- ily applied to genes that control fundamental pro- cesses of plant growth, differentiation, ... promoters. This research was supported by funds provided by the Kentucky Tobacco Research and Development Center, University of Kentucky. This paper (No. 07-06-068) is publis...
Ngày tải lên : 16/03/2014, 06:20
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