Báo cáo khoa học: Pfkfb3 is transcriptionally upregulated in diabetic mouse liver through proliferative signals docx
Báo cáo khoa học: Pfkfb3 is transcriptionally upregulated in diabetic mouse liver through proliferative signals docx
... that Pfkfb3 geneexpression is increased in streptozotocin-induced diabetic mouse liver. The Pfkfb3 ⁄ -3566 promoter construct linked to the luciferase reporter gene wasdelivered to the liver ... This promoter was upregulated in streptozotocin-induced diabetic mouse liver compared withtransfected healthy cohorts. In addition, increases were observed in Pfkfb3 mRNA and uPFK-2 protein ... immunostaining and hydrodynamic transfectionanalysis of Pfkfb3 ⁄ -3566 promoter construct. (A) uPFK-2 immuno-staining in control and diabetic mouse livers. Fixed liver samplesincluded in OCT...
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Báo cáo khoa học: AdipoR2 is transcriptionally regulated by ER stress-inducible ATF3 in HepG2 human hepatocyte cells pdf
... as insulin receptor sub-strates and adiponectin [8,9], resulting in obesity-relatedinsulin resistance [11–13]. In an in vitro model of ERstress induced by proteasome inhibition, the stressinduced ... adaptor protein that interacts with adiponectinreceptors, insulin and adiponectin signaling are nowconsidered to be linked in the peripheral organs ofinsulin action, such as the liver and skeletal ... as riskfactors for metabolic syndrome and atherosclerosis [1].Adiponectin, which is abundantly expressed in adiposetissue, is a circulating peptide hormone with directinsulin-sensitizing...
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Báo cáo khoa học: "Multilingual Computational Semantic Lexicons in Action: The WYSINNWYG Approach to NLP" docx
... finer grained semantics with respect to other languages (for instance en in Spanish is vague between the Contact and Container senses of the Location, whereas in English it is finer grained, ... ended up going to the (financial-institution OR river-shore), whatever this object might be!, instead of a) going to the financial- institution OR b) going to the river-shore. In this paper, ... computational linguistic account, where the concern of explaining a phenomenon is as important as pure computational concerns. In this paper, I adopt a computational linguistic perspec- tive, showing...
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Báo cáo khoa học: Schemes of flux control in a model of Saccharomyces cerevisiae glycolysis docx
... utilityof modelling in the study of T. brucei glycolysis has even ledto the coining of a new strategy for the investigation ofmetabolism: computer experimentation [11]. This is inten-ded to ... asecondary role for hexokinase and the remainder of main-chain glycolysis having only minimal relevance. This patternhas previously been observed in a study of glycolytic fluxcontrol in rat heart perfused ... space in whichits limiting rate is halved, while HXT(Vmax) is doubled.More detailed scanning (50 lmolÆmL)1Æmin)1<PFK,HXT(Vmax)<200lmolÆmL)1Æmin)1 in 15 lmolÆmL)1Æmin)1steps)...
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Báo cáo khoa học: "The Lie Detector: Explorations in the Automatic Recognition of Deceptive Language" docx
... that is dominant in the deceptive corpus, and thus likelyto be a characteristic of the texts in this corpus.Finally, a score significantly lower than 1 indicatesa class that is dominant in the ... truth/deception,and it is not bound to a particular topic.5 Identifying Dominant Word Classes in Deceptive Text In order to gain a better understanding of the char-acteristics of deceptive text, we devised a ... to appear in the deceptive corpus.We use the classes of words as defined in the Linguistic Inquiry and Word Count (LIWC),which was developed as a resource for psycholin-guistic analysis (Pennebaker...
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Báo cáo khoa học: "Producing Contextually Appropriate Intonation in an Information-State Based Dialogue System" docx
... alsodetermine IS using domain knowledge.3 Information StructureInformation structure (IS) is an inherent aspectof meaning; it is important for establishing co-herence and getting the intended ... Background/Focus partitioning dis-tinguishes between alternatives in context.Our approach to assigning IS is similar to Pre-vost's in assigning IS according to the precedingcontext, both in terms of ... variation using Steed-man's approach to IS in English (§3). In one ap-plication he handles question-answer pairs wherethe question intonation analysis in IS terms is used to motivate the IS of...
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Tài liệu Báo cáo khoa học: Interruption of triacylglycerol synthesis in the endoplasmic reticulum is the initiating event for saturated fatty acid-induced lipotoxicity in liver cells pdf
... FEBSInterruption of triacylglycerol synthesis in theendoplasmic reticulum is the initiating event for saturatedfatty acid-induced lipotoxicity in liver cellsMichalis D. Mantzaris1, Epameinondas ... TAG synthesiswas initially hindered following stearate administrationand was completely interrupted at longer incubationperiods. Interestingly, the interruption of TAG synthe-sis preceded ... variety of celltypes, including hepatocytes, to long-chain saturatedfatty acids (SFAs) led to increased expression of proin-flammatory cytokines, inhibition of insulin signaling,induction of endoplasmic...
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Tài liệu Báo cáo khoa học: NirF is a periplasmic protein that binds d1 heme as part of its essential role in d1 heme biogenesis pdf
... His, His41, in NirF byAla abolished binding of the heme to the protein.Known distal heme-binding residues, such as Met, Lysor Cys [18,19], were substituted for His41 in NirF. Nochanges in ... with the C-terminal d1heme-containing domain ofcytochrome cd1. Strikingly, the axial ligand of iron in d1heme in P. pantotrophus cd1(His200) is conserved in NirF (His41); this conservation ... Consideringthat NirF is colourless and has no absorbance in theUV–visible region, this shift of 50 nm in the spectrum is due to extreme changes in the d1heme environment.This binding of d1heme...
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Tài liệu Báo cáo khoa học: Bacitracin is not a specific inhibitor of protein disulfide isomerase pptx
... specificity for PDI is nonexistent. Bacitracin is also used medicinally to prevent infections in smallcuts and burns and to treat gastrointestinal infections. In addition, it is used as an animal ... pancreatic trypsin inhibitor (BPTI)refolding assay. BPTI is a widely studied protein con-taining three disulfides in the native form. In a gluta-thione-based refolding buffer, BPTI becomeskinetically ... disulfides of insulin arereduced by dithiothreitol, causing the aggregation andprecipitation of the B-chain of insulin, resulting in anincrease in light scattering that can be monitored byincreased...
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Tài liệu Báo cáo khoa học: It is all about resolution Meeting report based upon presentations at the 10th International Global BioMillennium 2006 symposium on molecular cell biology (Tbilisi, Georgia) docx
... degradesmRNAs harboring premature termination codons. In humans, nonsense-mediated mRNA is linked tosplicing, but in Drosophila and also in Caenorhabditiselegans, it occurs independently of introns. A ... aswas discussed by Javier F. Caceres (Edinburgh, UK).The trans-acting factors involved include both serine-arginine (SR) and heterogeneous nuclear ribonucleo-protein (hnRNP) A ⁄ B proteins, ... antagonisti cactivities in uencing different modes of alternative spli-cing in vivo, affecting tissue-specific or developmentalregulation of gene expression. Certain SR and hnRNPproteins shuttle...
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Từ khóa: báo cáo khoa học mẫubáo cáo khoa học y họcbáo cáo khoa học sinh họcbáo cáo khoa học nông nghiệpbáo cáo khoa học lâm nghiệpbáo cáo khoa học thủy sảnNghiên cứu sự biến đổi một số cytokin ở bệnh nhân xơ cứng bì hệ thốngNghiên cứu tổ chức pha chế, đánh giá chất lượng thuốc tiêm truyền trong điều kiện dã ngoạiNghiên cứu tổ hợp chất chỉ điểm sinh học vWF, VCAM 1, MCP 1, d dimer trong chẩn đoán và tiên lượng nhồi máu não cấpMột số giải pháp nâng cao chất lượng streaming thích ứng video trên nền giao thức HTTPNghiên cứu vật liệu biến hóa (metamaterials) hấp thụ sóng điện tử ở vùng tần số THzGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWANTrả hồ sơ điều tra bổ sung đối với các tội xâm phạm sở hữu có tính chất chiếm đoạt theo pháp luật Tố tụng hình sự Việt Nam từ thực tiễn thành phố Hồ Chí Minh (Luận văn thạc sĩ)Phát triển du lịch bền vững trên cơ sở bảo vệ môi trường tự nhiên vịnh hạ longNghiên cứu tổng hợp các oxit hỗn hợp kích thƣớc nanomet ce 0 75 zr0 25o2 , ce 0 5 zr0 5o2 và khảo sát hoạt tính quang xúc tác của chúngĐịnh tội danh từ thực tiễn huyện Cần Giuộc, tỉnh Long An (Luận văn thạc sĩ)Thiết kế và chế tạo mô hình biến tần (inverter) cho máy điều hòa không khíSở hữu ruộng đất và kinh tế nông nghiệp châu ôn (lạng sơn) nửa đầu thế kỷ XIXQuản lý nợ xấu tại Agribank chi nhánh huyện Phù Yên, tỉnh Sơn La (Luận văn thạc sĩ)BT Tieng anh 6 UNIT 2chuong 1 tong quan quan tri rui roGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtTÁI CHẾ NHỰA VÀ QUẢN LÝ CHẤT THẢI Ở HOA KỲ