THE MECHANISMS OF DNA REPLICATION pot

... retained in the central channel, while the other strand is moved to the external surface of the complex. The Mechanisms of DNA Replication 12 7. The business end: Polymerases at the origin The final ... recruitment of the replicative helicase to origins of DNA replication. The replicative helicase in S. cerevisiae is the minichromosome maintenance The...

Ngày tải lên: 30/03/2014, 00:20

... Subsequently, the hydrolysis of DnaA AT-rich region DnaA box DnaB DnaC Fig. 1. Cartoon of the assembly of the DNA replication machinery on the E. coli oriC region. Binding of DnaA (green ovals) to the DnaA ... [14]. Rather the role of ATP in the reaction is to serve as a switch that controls the activity of the helicase. The ATP bound form of DnaC severe...

Ngày tải lên: 07/03/2014, 21:20

... further found that the increase in the stability of the quintuple mutant is almost the same as the sum of the three individual stabilities [9,29]. Thus, the mutation(s) in each of the three regions ... similar to that of the natural thermophile by replacing a few amino- acid residues. Therefore, the thermophilic character of HT c-552 may depend on a few strong no...

Ngày tải lên: 24/03/2014, 03:21

... V max parameters) of the rate expressions of the various reactions. In the case of reversible reactions, we just consider the sum of the control coefficients of the forward and reverse reac- tions. This has the ... point of view, such systems are composed of only two interacting modes. The properties of these modes are so that one mode activates the other, whi...

Ngày tải lên: 30/03/2014, 16:20

... in the BNC more than once (CoocF > 1) the heuristic's accu- racy is increased by 11.0%. However, the number of potential compounds is reduced by a factor of three. The majority of the ... from the corpus are hapaxes (i.e., words that occurred only once). These represent 68.6% of the noun-noun sequences retrieved from the BNC; 57.7% of the hapaxes are valid...

Ngày tải lên: 22/02/2014, 02:20

... processing the rest of the input data if the workflow is robust (i.e. makes use of retry and parallelisation) and the error is confined to a WS (i.e. it does not affect the rest of the workflow). An ... of the interface (layout, colours, names, logos, etc.). The cate- gories that make up the classification system used in the Registry have been adapted to the NLP field...

Ngày tải lên: 22/02/2014, 03:20

... exploring the consequences of QCD for the spec- trum and decay of baryons; identifying the important degrees of freedom for the description of the majority of hadrons; and discovering the nature of the ... cnp@cc.uoa.gr The detailed investigation of the N—fA transition offers one of the best avenues to understand the structure of hadrons and the intr...

Ngày tải lên: 05/03/2014, 11:21

... nine’, ‘on top of the world’, ‘over the moon’ and ‘thrilled to bits’). They are dealt with in respect of their grammatical features including the syntactic functions and morphology, and their semantic ... here denote the property of feeling the pleasure to the extreme degree; they, therefore, cannot be modified by intensifiers of degree such as ‘very’, ‘too’, ‘extreme...

Ngày tải lên: 05/03/2014, 12:20

... patients: positioning them, their newborns and their families at the center of their care and making them an integral part of their health care decision- making team. Each chapter of TIOP III illustrates ... data at the beginning. The American Hospital Association, the Federation of American Hospitals and the 6 marchofdimes.com Toward Improving the Outcome of Pregna...

Ngày tải lên: 05/03/2014, 13:20