Anecdotes of the late Samuel Johnson potx

Anecdotes of the late Samuel Johnson potx

Anecdotes of the late Samuel Johnson potx

... all' improviso, in the same manner: Information prepared by the Project Gutenberg legal advisor 19 Anecdotes of Johnson The Project Gutenberg Etext of Anecdotes of Johnson by Hesther Lynch Piozzi Copyright ... applauded the number of their books and the graces of their style. "They have few sentiments," said he, "but they express them neatly; th...

Ngày tải lên: 29/03/2014, 23:20

65 215 0
Báo cáo khoa học: Exosites mediate the anti-inflammatory effects of a multifunctional serpin from the saliva of the tick Ixodes ricinus potx

Báo cáo khoa học: Exosites mediate the anti-inflammatory effects of a multifunctional serpin from the saliva of the tick Ixodes ricinus potx

... the helices. The mean surface accessibility of the predicted epitopes on the Iris 3D structures was calculated by averaging the accessible surface area of the peptide residues using the Shrake ... USA). Their interaction with a model membrane is simulated by the IMPALA method [42]. This step allows an evaluation of the hydrophobic ⁄ hydrophilic segregation (i.e. the...

Ngày tải lên: 07/03/2014, 01:20

12 500 0
Báo cáo khoa học: YidC is required for the assembly of the MscL homopentameric pore potx

Báo cáo khoa học: YidC is required for the assembly of the MscL homopentameric pore potx

... insertion of MscL. In the absence of YidC, assembly of the homopentameric MscL complex was strongly reduced, suggesting a late role for YidC in the biogenesis of MscL. The data are consistent with the view ... traverse the inner membrane, thus validating the assay condi- tions. Western blot analysis of samples taken prior to the pulse labelling confirmed the deple...

Ngày tải lên: 07/03/2014, 02:20

9 466 0
Báo cáo khoa học: Mapping of the 45M1 epitope to the C-terminal cysteine-rich part of the human MUC5AC mucin potx

Báo cáo khoa học: Mapping of the 45M1 epitope to the C-terminal cysteine-rich part of the human MUC5AC mucin potx

... the reactivity of the mAb against myc. One reason for the requirement of the N-terminal 91 amino acids could be that these are necessary for the correct folding of the protein, and that the lack of them ... epitopes located in the MUC5AC C-terminal cysteine-rich part. Further localization of the epitopes of 45M1, 2-12 M1 and 166M1 In order to further locate the...

Ngày tải lên: 07/03/2014, 05:20

9 331 0
Uniform prices for differentiated goods: The case of the movie-theater industry potx

Uniform prices for differentiated goods: The case of the movie-theater industry potx

... in the persistence of the practice. The paper continues as follows. Section 2 presents the puzzle of uniform prices at the movie theater, studies the patterns of the demand for movies at the theater, ... of product differentiation. Movie- goers normally pay one price for all movie tickets, regardless of the popularity of the movie, the day of the week, an...

Ngày tải lên: 07/03/2014, 10:20

26 1K 0
Báo cáo khoa học: A ribonuclease zymogen activated by the NS3 protease of the hepatitis C virus potx

Báo cáo khoa học: A ribonuclease zymogen activated by the NS3 protease of the hepatitis C virus potx

... activity of unactivated zymogens is a result of both a smaller value of k cat and a larger value of K m . The k cat ⁄ K m value of the unactivated 1C zymogen is 33-fold higher than that of the unactivated ... catalytic residues. The only difference between the unactivated 2C and 1C zymogens is the sulfur atom of the cysteine residue in the P2 position of the...

Ngày tải lên: 07/03/2014, 11:20

9 392 0
Báo cáo khóa học: Structural properties of the protein SV-IV potx

Báo cáo khóa học: Structural properties of the protein SV-IV potx

... identified by the mass increase of 42 mass units. The relative level of acetylation of a peptide was estimated on the basis of the intensity ratio of the native and acetylated species. From the data ... electrospray MS. Theoretical mass is the mass calculated on the basis of the protein amino-acid sequence. The relative abundance refers to the ratio of the...

Ngày tải lên: 07/03/2014, 14:20

9 416 0
BIOENGINEERING OF THE SKIN Skin Biomechanics potx

BIOENGINEERING OF THE SKIN Skin Biomechanics potx

... to 80% of the dry weight of skin consists of collagen. The most abundant collagen types in skin are types I and III; the former accounts for 80% of the total collagen content of skin and the latter ... I Secretion FIGURE 1.2 The intracellular and extracellular steps of the synthesis of fibrillar collagen. the rate of ongoing collagen synthesis.1.l2,13 In adult...

Ngày tải lên: 15/03/2014, 09:20

321 324 0
MAORI and SETTLER A STORY OF THE NEW ZEALAND WAR potx

MAORI and SETTLER A STORY OF THE NEW ZEALAND WAR potx

... congratulated themselves on the arrangements that they had made as they saw the hesitating way in which the rest of the passengers took their places, and the looks of inquiry and doubt they cast ... driver, and the roof was piled high with luggage. The other cab contained the two Grimstones and the rest of the luggage. The Renshaws were[Pg 32] already acquainted...

Ngày tải lên: 15/03/2014, 12:20

259 366 0
Báo cáo khoa học: Alpha 1,3-fucosyltransferase-VII regulates the signaling molecules of the insulin receptor pathway potx

Báo cáo khoa học: Alpha 1,3-fucosyltransferase-VII regulates the signaling molecules of the insulin receptor pathway potx

... caused by the promotion of InR signaling, because activated PKB can stimulate the phosphorylation of GSK-3 and inhibit the activity of GSK-3. GSK-3 phosphorylates b-catenin and stimulates the ubiquitination ... This may reveal the role of the sugar chains on InR in the pathogenesis of diabetes. In summary, the cDNA of a1,3-FucT-VII is able to regulate the phospho...

Ngày tải lên: 16/03/2014, 12:20

13 354 0
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