Báo cáo khoa học: Hepatocyte growth factor activator is a serum activator of single-chain precursor macrophage-stimulating protein potx

... 5¢-ATGGTGGGAATGGGTCAGAAG-3¢ and 5¢-CA CGCAGCTCATTGTAGAAGG-3¢. Another primer pair used for SerpinA3 was ACTas5-ACTas3: 5¢-GAATCC ACCAGCTACATCCA-3¢ and 5¢-GTGCCCTCCTCAAA TACATCA-3¢. Western blot assay The cells ... pcDNA3.1-GST-Nur77 plasmid. pSilencer-shNur77 was prepared by overlapping strategy with primers 5¢-gacGGATCCgcagtccagccatgctccttt caagagaaggagcatg-3¢ (with BamHI), 5¢-cggAAGCTTtATC...

Ngày tải lên: 23/03/2014, 07:20

... Tsubouchi H, Naka D, Takahashi K, Okigaki M, Arakaki N, Nakayama H, Hirono S, Sakiyama O, Takahashi K et al. (1989) Molecular cloning and sequence analysis of cDNA for human hepatocyte growth factor. ... Shimomura T, Miyazawa K, Komiyama Y, Hiraoka H, Naka D, Morimoto Y & Kitamura N (1995) Activation of hepatocyte growth factor by two homologous proteases, blood-coagulation...

Ngày tải lên: 15/03/2014, 11:20

... substrates pro -hepatocyte growth factor and pro -macrophage-stimulating protein. Abbreviations EGF, epidermal growth factor; HAI, hepatocyte growth factor activator inhibitor; HGFA, hepatocyte growth ... (2009) Hepatocyte growth factor activator is a serum activator of single-chain precursor macro- phage-stimulating protein. FEBS J 276, 3481–3490...

Ngày tải lên: 15/03/2014, 11:20

... of human plasma kallikrein and factor XIa by protein C inhibitor. Biochemistry 27, 4231–4237. 8 Wakita T, Hayashi T, Tamaru H, Nishioka J, Akita N, Asanuma K, Kamada H, Gabazza EC, Ido M, Kawamura ... regeneration. Abbreviations APC, activated protein C; BrdU, bromodeoxyuridine; HAI, hepatocyte growth factor activator inhibitor; HGF, hepatocyte growth factor; HGFA, hepa...

Ngày tải lên: 22/03/2014, 21:21

... human kallik- rein 1-related peptidases. FEBS J 275, 1003–1017. 26 Kawaguchi M, Orikawa H, Baba T, Fukushima T & Kataoka H (2009) Hepatocyte growth factor activator is a serum activator of single-chain ... plasma of healthy individuals is around 40 nm ( 4 lgÆmL )1 ) [10], indi- cating its relative abundance as a plasma protein. The activated form of HGFA is...

Ngày tải lên: 22/03/2014, 21:21

... activator of single-chain precursor macrophage-stimulating protein Makiko Kawaguchi, Hiroshi Orikawa, Takashi Baba, Tsuyoshi Fukushima and Hiroaki Kataoka Section of Oncopathology and Regenerative ... proteinases (cell surface activator) , such as matriptase [9]. Matriptase is also a potent activator of pro-HGF/SF [12,30]. The second pathway is mediated by humoral act...

Ngày tải lên: 29/03/2014, 23:20

... JW & Condra C (1992) An inhi- bitor of collagen-stimulated platelet activation from the salivary glands of the Haementeria of cinalis leech. I. Identification, isolation, and characterization. ... substances have been discovered that inhibit platelet adhesion and activation. Three such molecules, LAPP (an approximately 13 kDa leech antiplatelet protein isola- ted from Haementeria o...

Ngày tải lên: 30/03/2014, 09:20

... recording at 80 °C for 30 s. Similarly b-actin cDNA was also amplified using primers b-actin F (sense) (5¢-AGAAAATCTGGC ACCACACC-3¢) and b-actin R (antisense) (5¢-TAG- CACAGCCTGGATAGCAA-3¢), and served ... purification and characterization of an alkaline dipeptide naphthylamidase (Arg–Arg–NAase) of the rat skin. Arch Klin Exp Dermatol 236, 267–281. 2 de Bersaques J (1972) Peptidases and nap...

Ngày tải lên: 29/03/2014, 09:20

... Aichi Cancer Center Hospital, Nagoya, Japan Identification of epidermal growth factor, epidermal growth factor receptor and ERBB family proteins Epidermal growth factor (EGF) was originally isolated by ... other activated genes in lung cancers are also discussed. Abbreviations ALK, anaplastic lymphoma kinase; BAC, bronchioloalveolar cell carcinoma; EGF, epidermal growth factor;...

Ngày tải lên: 16/02/2014, 09:20

... lung can- cer with epidermal growth factor receptor mutations. Br J Cancer 95, 998–1004. 16 Sutani A, Nagai Y, Udagawa K, Uchida Y, Koyama N, Murayama Y, Tanaka T, Miyazawa H, Nagata M, Kanazawa ... epidermal growth factor receptor gene mutations. Lung Cancer 64, 314–318. 22 Morita S, Okamoto I, Kobayashi K, Yamazaki K, Asahina H, Inoue A, Hagiwara K, Sunaga N, Yanagitani N, Hida T...

Ngày tải lên: 16/02/2014, 09:20