Báo cáo khoa học: Wisely chosen paths – regulation of rRNA synthesis Delivered on 30 June 2010 at the 35th FEBS Congress in Gothenburg, Sweden potx
Báo cáo khoa học: Wisely chosen paths – regulation of rRNA synthesis Delivered on 30 June 2010 at the 35th FEBS Congress in Gothenburg, Sweden potx
... Regulation of rRNA synthesis FEBS Journal 277 (2010) 462 6–4 639 ª 2010 The Author Journal compilation ª 2010 FEBS 4639 THE FEBS ⁄ EMBO WOMEN IN SCIENCE LECTURE Wisely chosen paths – regulation of rRNA ... phosphorylation of the C-terminal activation domain of UBF [28], under- scoring the importance of UBF phosphorylation in the control...
Ngày tải lên: 29/03/2014, 21:20
Báo cáo khoa học: How a lipid mediates tumour suppression Delivered on 29 June 2010 at the 35th FEBS Congress in Gothenburg, Sweden pdf
... functions of PtdIns3P [29]. Additional PtdIns3P-binding proteins that do not contain FYVE or PX domains include the Proppin ⁄ WIPI proteins, which bind PtdIns3P [and to some extent the related PtdIns(3,5)P 2 ] ... deubiquitinat- ed by deubiquitinating enzymes recruited by ESCRT-III [61], and ESCRT-III serves to sever the neck of the forming invagination, thereby securing the inc...
Ngày tải lên: 06/03/2014, 01:23
Báo cáo khoa học: Pharmacology of vascular endothelium Delivered on 27 June 2004 at the 29th FEBS Congress in Warsaw pptx
... hydrophilic pravastatin) at a concentration of 30 lm mobilize free cytoplasmic calcium [Ca 2+ ] i to 3 0–5 0% of that induced by Bk at a concentration of 10 nm. In the case of simvastatin and lovastatin, this ... their stimulatory effect on the endothelial generation of PGI 2 and NO • . There are other propositions concerning the mechan- ism of endothelial action...
Ngày tải lên: 07/03/2014, 21:20
Báo cáo khoa học: The yeast stress response Role of the Yap family of b-ZIP transcription factors The PABMB Lecture delivered on 30 June 2004 at the 29th FEBS Congress in Warsaw potx
... preventing the formation of the competing Orp1 Cys36-Cys82 disulfide bond. Once activated, the Yap1 NES that lies within the c-CRD is masked leading to its retention in the nucleus and the up -regulation ... unpublished data). Nuclear localization of the fusion protein correlates not only with activation of FRM2 transcription, but also with growth in increasing concent...
Ngày tải lên: 30/03/2014, 16:20
Báo cáo khoa học: A decade of Cdc14 – a personal perspective Delivered on 9 July 2007 at the 32nd FEBS Congress in Vienna, Austria pdf
... this question. In particular, I was interested in determining the role of CDKs in the regulation of mitotic Clb cyclin degradation, by examining the consequences of CDK inactivation on mitotic Clb cyclin ... is the case. Cdc14 is the phosphatase that dephosphorylates Cdh1. Its inactivation has the most dramatic effect on Clb cyclin degradation. CDC15 is a compone...
Ngày tải lên: 23/03/2014, 06:20
Báo cáo khoa học: Diversity of human U2AF splicing factors Based on the EMBO Lecture delivered on 7 July 2005 at the 30th FEBS Congress in Budapest pptx
... Schematic representation of protein–protein and protein–RNA interactions mediated by the U2AF heterodimer during the early steps of spliceosome assembly. Binding of the U2AF heterodimer to the ... for splicing of at least certain pre-mRNAs in vitro [19]. The N-terminal amino acids 8 5–1 12 of U2AF 65 interact with U2AF 35 , and this association further strengthens t...
Ngày tải lên: 23/03/2014, 10:20
Báo cáo khoa học: Mitochondrial calcium signalling in cell death Delivered on 1 July 2004 at the 29th FEBS Congress in Warsaw pptx
... Ca 2+ -dependent inhibition of cel- lular responses. The other physiological regulation of mitochondria that has been studied in relation to Ca 2+ signalling is the state of fusion and fission. The study of ... up in recent years indicating that metabolic regulation is only one of the roles of the mitochondrial Ca 2+ signal. It now appears evident that massive Ca...
Ngày tải lên: 30/03/2014, 20:20
Báo cáo khoa học: Apoptosis and autophagy: Regulation of apoptosis by DNA damage signalling – roles of p53, p73 and HIPK2 ppt
... activation of checkpoint kinases belonging to the family of phospha- tidylinositol-3-OH-kinase-like protein kinases. The currently best studied phosphatidylinositol-3-OH- kinase-like protein kinase ... replication in the S phase. Here, single-stranded DNA becomes opsonized by the replication protein A, which recruits ATR via the ATR-interacting protein to the DNA lesions and...
Ngày tải lên: 16/03/2014, 00:20
Báo cáo khoa học: Gonadotropin-releasing hormone: regulation of the GnRH gene pot
... Ref.28 –1 571 –1 780/ –1 772 Oct–1 (–1 569/ –1 562) Ref.49 GATA (–1 748/ –1 743) Ref.10 –1 746/ –1 738 –1 736/ –1 728 GATA (–1 715/ –1 710) Ref.10 –1 697/ –1 689 C/EBP (–1 684/ –1 676) Oct–1 (–1 10/ –8 8) Ref.12 ... without Oct-1. Within those Pbx1 ⁄ Prep1-binding motifs, only mutation in the )1749 bp binding site can eliminate t...
Ngày tải lên: 16/03/2014, 04:20
Báo cáo khoa học: Structure, expression and regulation of the cannabinoid receptor gene (CB1 ) in Huntington’s disease transgenic mice ppt
... pointing a rrows indicate the relative positions of the 5¢- ends of the cDNA clone s identified by 5¢-RLM-RACE compared to the exon/intron organization of the CB1 gene. The major transcription initiation ... in HD mouse brain. T his supports the hypothesis that the rate of transcription of CB1 in the striatum of symptomatic R6/2 mice is similar to the rate...
Ngày tải lên: 16/03/2014, 18:20