Báo cáo khoa học: Structural basis for the interaction between dynein light chain 1 and the glutamate channel homolog GRINL1A docx
... +34 915 6424 31 Tel: +34 917 459 511 E-mail: mbruix@iqfr.csic.es (Received 12 January 2 010 , revised 11 March 2 010 , accepted 15 March 2 010 ) doi :10 .11 11/ j .17 42-4658.2 010 .07649.x Human dynein light chain ... values for the 20 lowest-energy conformers of the best cluster are 0. 71 ± 0 .11 A ˚ for the backbone and 1. 11 ± 0.09 A ˚ for the heavy atoms....
Ngày tải lên: 29/03/2014, 09:20
... 17 5 .1 1 91. 1 19 1 .1 Yes 3.40 ± 0.45 2 611 ± 19 6 767 ± 18 3 D-Arginine 17 5 .1 1 91. 1 17 5.2 No – – – L-Homoarginine 18 9 .1 205 .1 205.0 Yes 7.05 ± 2.35 8 31 ± 16 6 11 8 ± 47 .1 L-Canavanine 17 7 .1 193 .1 193 .1 ... 17 .52 14 .18 13 .98 No. of atoms 2954 3232 317 0 No. of water molecules 288 4 51 3 81 No. of heterogens 13 10 12 rmsd from ideal Bond lengths...
Ngày tải lên: 16/03/2014, 02:20
... P2 1 2 1 2 1 P2 1 2 1 2 1 P2 1 2 1 2 1 P2 1 2 1 2 1 P2 1 2 1 2 1 P2 1 2 1 2 1 Beamline X 11 X 11 X 11 X 11 X 11 ID14 -1 Unit cell: a ¼ 56.86 A ˚ 56.73 A ˚ 57.28 A ˚ 56.80 A ˚ 56. 71 A ˚ 56.78 A ˚ b ¼ 83. 21 A ˚ 83.36 A ˚ 82.68 A ˚ 83 .14 A ˚ 83.59 ... binding Table 1. Data collection and refinement statistics. Ligand- removed Mannose GlcNAc (b1–2)...
Ngày tải lên: 23/03/2014, 11:20
Báo cáo khoa học: Structural basis for the changed substrate specificity of Drosophila melanogaster deoxyribonucleoside kinase mutant N64D docx
... 240 Wildtype b 1. 2 29.5 1 14.2 1. 2 · 10 7 1 dC N45D 0.9 3.4 1 1.6 1. 8 · 10 6 4 N64D 11 8 3.4 0.8 1. 6 13 559 5 31 N45D ⁄ N64D a 96.4 8.3 1 4.04 42000 17 1 Wildtype b 2.3 34.2 1 16.5 7.2 · 10 6 1 dA N45D 11 9 3.8 ... 0 .15 6 1 0.076 38 605 Wildtype b 665 31. 3 1 15 .1 23000 1 AZT N45D 11 .7 0.06 1 0.03 2564 1. 7 N64D 11 .1 0.074 0.8 0.037 3333 1. 3 N...
Ngày tải lên: 30/03/2014, 20:20
Tài liệu Báo cáo khoa học: Structural basis for cyclodextrin recognition by Thermoactinomyces vulgaris cyclo⁄maltodextrin-binding protein ppt
... reflections 11 1 339 11 1 287 18 1 528 Unique reflections 15 803 15 798 47 6 91 Completeness 96.7 (89.7) b 96.5 (87.7) b 10 0.0 (10 0.0) b I ⁄ r(I) 43.5 (11 .5) b 43.3 (11 .3) b 24.0 (8.6) b R merge (%) a 18 .7 ... and Glu3 61 form protru- sions at the entrance of the cleft, and the distance between Nf of Lys229 and Oe1 of Glu3 61 is 16 .7 A ˚ . On the other hand, th...
Ngày tải lên: 19/02/2014, 00:20
Báo cáo khoa học: Structural basis for recognition of Co2+ by RNA aptamers pot
... RNA ligands, including the N7 atom of purines. Therefore, there is the possible involvement of the N7 atom of the neigh- boring tandem guanines, G27 and G28 or G37 and G38 in aptamer no. 18 , as ... (2008) 16 51 16 62 ª 2008 The Authors Journal compilation ª 2008 FEBS 16 53 these purines are located in the single-stranded region accessible for chemical probing [19 ]. Thus...
Ngày tải lên: 16/03/2014, 06:20
Báo cáo khoa học: Structural basis for substrate recognition by Erwinia chrysanthemi GH30 glucuronoxylanase potx
... +4 21 2 59 41 0222 Tel: +4 21 2 59 41 0275 E-mail: chempbsa@savba.sk (Received 17 December 2 010 , revised 10 April 2 011 , accepted 13 April 2 011 ) doi :10 .11 11/ j .17 42-4658.2 011 .0 812 7.x Xylanase A from the ... xylanase A–ligand complex FEBS Journal 278 (2 011 ) 210 5– 211 6 Journal compilation ª 2 011 FEBS. No claim to original Slovakian government works 211 1 (formerly G...
Ngày tải lên: 22/03/2014, 16:20
Báo cáo khoa học: Structural basis for stereo-specific catalysis in NAD+-dependent (R )-2-hydroxyglutarate dehydrogenase from Acidaminococcus fermentans pptx
... red for arginine, blue for glutamate and aspartate, green for histidine, cyan for polar, orange for aromatic and aliphatic side chains, brown for Thr77–Gly79 and dark red for Gly153-Asp176. The ... 533627 ⁄ 30959 714 20 ⁄ 19 159 715 81 ⁄ 19 152 60 515 ⁄ 19 338 Completeness (%) a 98.8 (93.9) 98.4 ( 91. 9) 98.4 ( 91. 8) 99.0 (97.8) Mean I ⁄ r a 28 .17 (6.84) 18 .34...
Ngày tải lên: 23/03/2014, 13:20
Báo cáo khoa học: Structural basis for poor uracil excision from hairpin DNA An NMR study pptx
... G 6 (H1)–C 21 (H 41/ H42), G 7 (H1)–C 20 (H 41/ H42), A 8 (H2)–T 19 (H3), T 9 (H3)– A 18 (H2), C 10 (H 41/ H42)–G 17 (1NH) and C 11 (H 41/ H42)– G 16 (H1) establish a hydrogen bonded base-pairing between G 6 :C 21 (G 6 and ... locked into t, g + and t conformations, respectively, similar to the stem. On the other hand, for T 14 and T 15 ,thef is locked into...
Ngày tải lên: 31/03/2014, 09:20
Báo cáo khoa học: Structural requirements for Caenorhabditis elegans DcpS substrates based on fluorescence and HPLC enzyme kinetic studies pdf
... K m (min )1 Æmg )1 ) Fluorescence method m 7 GpppG m 7 GMP + GDP 1. 17 ± 0 .14 1. 53 ± 0 .11 1. 30 ± 0 .18 m 7 GpppA m 7 GMP + ADP 0.60 ± 0 .11 1. 09 ± 0 .11 1. 83 ± 0.38 m 7 Gpppm 6 Am 7 GMP + m 6 ADP 1. 03 ... m 6 ADP 1. 03 ± 0 .16 1. 33 ± 0 .12 1. 30 ± 0.23 m 7 Gpppm 7 Gm 7 GMP + m 7 GDP 1. 12 ± 0 .14 0. 91 ± 0 .10 0. 81 ± 0 .13 m 7 Gpppm 2¢-O Gm 7 GMP + m 2¢-O GDP 1. 23...
Ngày tải lên: 29/03/2014, 09:20