Báo cáo khoa học: Ets-1/ Elk-1 is a critical mediator of dipeptidyl-peptidase III transcription in human glioblastoma cells pdf

... contains two arginine ⁄ glycine-rich (RGG) motifs that are characteristic of RNA-binding proteins, and an alanine-rich carboxy-terminal sequence that could be involved in protein–protein interactions. Interestingly, ... homologs are poly (A) polymerases. Proc Natl Acad Sci USA 101, 4407–4412. 18 Nakanishi T, Kubota H, Ishibashi N, Kumagai S, Watanabe H, Yamashita M, Kashiwabara S, Miyado...

Ngày tải lên: 07/03/2014, 05:20

... Ac-YVAD-AMC is a substrate for caspase 1; Ac-IETD-AMC is a substrate for caspase 8 and 10; Ac-LEHD-AMC is a substrate for caspases 2, 4, 5 and 9. Ac-DVPD-AMC, Ac-DPSD-AMC and Ac-ESQD-AMC are tetra peptide ... horizontal line indicates an induction value of 1. Fig. 6. Comparison of the ability of recombinant human caspases to cleave DPSD-AMC. The human recombinant caspase...

Ngày tải lên: 19/02/2014, 13:20

... TAT ATG T Weak 3 aa 2 ⁄ 4 55067 TCA ATG C Weak 58 aa 3 33 39% 60929 60933 60939 GTA ATG C TGC ATG T TCC ATG G G Adequate Weak Adequate 13 aa 33 aa 31 aa 3¢ 76 49% – 4¢ 56 61% 61041 GGA ATG T Adequate ... the carboxy tail of Hu-K4. The apparent molecular mass of 65 kDa is higher than the calculated molecular mass of 55 kDa for Hu-K4 hinting at a post-translational modification, e.g. g...

Ngày tải lên: 19/02/2014, 17:20

... (2002) Interaction of the CC-chemokine RANTES with glycosaminogly- cans activates a p44 ⁄ p42 mitogen-activated protein kin- ase-dependent signaling pathway and enhances human Syndecan-4 is an auxiliary ... (Fig. 5A, lane 1). These data strongly indicate that SDF-1 induces a rapid and significant increase in the tyrosine phosphorylation of SD-4 on HeLa cells and that a physic...

Ngày tải lên: 16/03/2014, 18:20

... 6803 [7], indicating a structural or a functional role for both pigments. A structural role was indicated in a Chl-less mutant that was reported to lack accumulation of the Cyt b 6 f complex in Clamydomonas ... show in etio- plasts that a Cyt b 6 f complex can be isolated with a molecular mass and subunit composition indistinguish- able from dimeric Cyt b 6 f isolated from...

Ngày tải lên: 23/03/2014, 07:20

... Bacterial IscU is a well folded and functional single domain protein Salvatore Adinolfi 1 , Francesca Rizzo 1 , Laura Masino 1 , Margie Nair 1 , Stephen R. Martin 1 , Annalisa Pastore 1 and ... solvent is observed. Binding of a paramagnetic species leads instead to major Fig. 4. Probing the aggregation state of IscU. (Top) Calibration curve for apparent molecular mass determination...

Ngày tải lên: 23/03/2014, 12:20

... pre-pro enzyme including an N-terminal chaperone like domain, the catalytic domain and two similar C-ter- minal domains with unknown structure and function. The N-terminal pro domain is autocatalytically ... atoms of the side chains of Asp11, Asp14 and Asp21, the amide oxygen atom of Gln15 and the carbonyl oxygen atoms of Asp11 and Asn23 (Fig. 3) in an arrangement similar to what...

Ngày tải lên: 19/02/2014, 07:20

... contain a PAS domain. Therefore, in the case of A. thaliana,thePASandPAC motifs are inseparable, indicating that the annotation of these proteins as containing only PAS or PAC motifs is questionable. ... PAS proteins, is depicted in Fig. 3. We conclude from this alignment that all PAS-annotated A. thaliana proteins also contain a PAC motif, and conversely that all PAC- annot...

Ngày tải lên: 19/02/2014, 12:20

... statistical breadth and convenience of automatic expansion. Fortunately, statistical corpus analysis is an ob- vious area of overlap for IR and FLP. Distribu- tional analyses of large corpora ... embedded within a larger sea of noise. Creative IR can be used to explore this idea space. Each creative query is a jumping off point in a space of lexicalized ideas that is i...

Ngày tải lên: 07/03/2014, 22:20

... support as separately definable knowledge within studies of aphasia. There is a vast literature concerning what aspects of language are indepen- dently affected in aphasia that has been used as a ... to access meanings.) Using spreading activation, the syntactic category aspect of each meaning in turn activates the category's meaning in the grammar space represe...

Ngày tải lên: 08/03/2014, 18:20