Báo cáo khoa học: Mucin-type O-glycosylation – putting the pieces together docx

... that they can make any decision they want as an open-ended ideal. This puts them in the position of being buyers in a consumer’s market. By asking them to make a choice, they imply that their authority ... life-in-death [4]. Patients may be stalled in suspended animation; they are not alive in the sense the we enjoy life but neither are they able to die as long as nutrition, hydration,...

Ngày tải lên: 25/10/2012, 10:45

... (2011) 101 0–1 019 ª 2011 The Authors Journal compilation ª 2011 FEBS whether this loop aims only at activating the male path- way, or repressing the female one, or both. In zebrafish, the transcription ... genetic studies led to the view that, across the animal kingdom, the gene-regulatory cascades triggering sexual develop- ment bear little resemblance to each other. As a res...

Ngày tải lên: 14/02/2014, 19:20

... ligands. The additional water occupied the postulated superoxide bind- ing site. The thermal stability of the enzyme was compared with superoxide dismutase from Thermus thermophilus, a thermophilic ... ApeSODs. (A–C) The orange map represents the r A -weighted F o )F c electron density map at the 3 r level, where the indicated residues are excluded from the calculation of t...

Ngày tải lên: 14/02/2014, 22:20

... to the catalytic site of the R1E subunit. As reported in the Results, upon completion of substrate conversion, the radical is then rapidly passed back from the R1E subunit to the tyrosyl of the ... other class 1 RNRs or, instead, is a result of the interaction of the R2F with the inactivated (oxidized) form of the R1E. We consider the first option unlikely. Under these...

Ngày tải lên: 15/02/2014, 01:20

... in apoptosis, the relationship of these two molecules is still largely unknown. The aim of the current study was to investigate the potential involvement of nucleolin ⁄ C23 in the antiapoptotic ... accompanied by the appear- ance and an increase in the 80 kDa fragment (Fig. 2). Although both the untransfected cells and the cells transfected with the vector alone started to...

Ngày tải lên: 16/02/2014, 09:20

... ed 3 phuang thdc the bien tren sdng: dpe, dpe kit hpp vdi noi va noi (dng khiu). LDgc Ekyc- theo td didn tieng Viet, li phit thinh lii nhung dieu di dupe viii ra, theo dung trinh ... trong vdn ban quy djnh each dgc cua nha bdo. Ngudi dgc khdng the tuy tien ngdt cdu, ngat doan, ngtmg nghi theo y thich, ma phai men theo dau chdm, ddu phay, cdch su dung ngd doan eua tdc g...

Ngày tải lên: 17/02/2014, 05:20

... 3′UTR pri-23a pcDNA3 miR-23a ASO ASO-NC + – – – – – – + – – – – – + + – – – – + – + – – – + – – + – – + – – – + 2833 2843 3123 3133 Fig. 3. IL6R is a direct target of miR-23a. (A) The IL6R 3¢ UTR carries three ... 277 (2010) 372 6–3 734 ª 2010 The Authors Journal compilation ª 2010 FEBS 3727 base pairing w...

Ngày tải lên: 18/02/2014, 04:20

... and the E chain from TtAKb-free, and red indicates the distance between the B chain from TtAKb-Thr and the F chain from TtAKb-free. The regions shown in A–E are: A, 4 2–4 5; B, 4 6–5 0; C, 5 1–5 8; ... 3125 seen on the map. The electron densities of the sections (residues 5 4–5 6 in chains A and D, residues 5 3–5 9 in chain B, residues 5 5–5 6 in chain C, residues...

Ngày tải lên: 18/02/2014, 08:20

... consequently, the 20E- dependent activation is blocked. The presence of 20E, however, favors the formation of the AaEcR⁄ AaUSP heterodimer [13], indicating that the regulation of the activity of these ... al. 1248 FEBS Journal 276 (2009) 123 3–1 254 ª 2009 The Authors Journal compilation ª 2009 FEBS their putative functions. Taken together, these data support our hypothesis t...

Ngày tải lên: 18/02/2014, 13:20

... transition for cJun–FosW can be estimated based on the m eq value ()6.8) taken from the cJun(R)–FosW(E) mutant (Table 1, Fig. 5). On the basis of these data, it appears that the parent cJun– FosW molecule ... increased ‘residency time’ for the protein–antagonist complex. It has been speculated that the longer the antagonist–target inter- action prevails, the higher the effica...

Ngày tải lên: 18/02/2014, 13:20