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Báo cáo khoa học: Nuclear factor kappa B and tumor necrosis factor-alpha modulation of transcription of the mouse testis- and pre-implantation development-specific Rnf33⁄Trim60 gene pot

Báo cáo khoa học: Nuclear factor kappa B and tumor necrosis factor-alpha modulation of transcription of the mouse testis- and pre-implantation development-specific Rnf33⁄Trim60 gene pot

Báo cáo khoa học: Nuclear factor kappa B and tumor necrosis factor-alpha modulation of transcription of the mouse testis- and pre-implantation development-specific Rnf33⁄Trim60 gene pot

... located in the single intron of the Rnf33 gene adjacent to exon 1; the intronic jB was targeted by the p65 ⁄ RelA and p50 ⁄ NFjB1 nuclear < /b> factor-< /b> jB(NF-jB) subunits, and the jB-dependent transcrip-tion ... FEBS Nuclear < /b> factor < /b> kappa < /b> B and tumor necrosis factor-< /b> alpha modulation of transcription of the mouse testis- and pre-implantation development-specific Rnf33⁄Trim60 gene Kong-Bung Choo1,2,3, Min-Chuan ... regulated by an intron-ic jB sequence modulated by the NF-jB subunits p65 and p50, and also by TNF-a. Although p65 is proba-bly expressed in the oocyte and the pre-implantation embryo, it remains...
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Báo cáo khoa học: Nuclear factor TDP-43 can affect selected microRNA levels pptx

Báo cáo khoa học: Nuclear factor TDP-43 can affect selected microRNA levels pptx

... groove binder (MGB) probe, let- 7b 5¢-S-carboxyfluorescein (FAM)-agtgatgttgcccc-MGB 3¢, wasdesigned to have a 5¢ FAM and an MGB at the 3¢ end. The TaqMan MGB probe was synthesized by Applied Bio-systems. ... transfection of these constructs. In this type of experiment, the level of the interac-tion between the endogenous let- 7b and miR-663 and the expression vector determined the levels of luciferase ... TDP-43,even in the presence of all other nuclear < /b> competingproteins (Fig. S2).We also examined the sequences of all the othermiRNAs, and noted that within the sequence of the miR-663 precursor (the second...
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Báo cáo khoa học:

Báo cáo khoa học: "Automated Essay Scoring Based on Finite State Transducer: towards ASR Transcription of Oral English Speech" docx

... AES situation that theyare not suitable for the characteristic. The impact of the first problem can be reducedby either perfecting the results of the ASR system orbuilding the AES system which ... experiments will be done inboth transcriptions. A better understanding of the difference in the CRR transcription and the ASR transcription from the low score to the high scoreis shown in Table 2, where ... distur-brance for the methods. Therefore, the conventionalBOW methods are no longer appropriate because of the characteristic of the ASR result.To tackle the two problems described above, weapply...
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Báo cáo khóa học: Noncytotoxic ribonuclease, RNase T1, induces tumor cell death via hemagglutinating virus of Japan envelope vector ppt

Báo cáo khóa học: Noncytotoxic ribonuclease, RNase T1, induces tumor cell death via hemagglutinating virus of Japan envelope vector ppt

... formesothelioma [1]. The first step in RNase cytotoxicity is the internalization of the protein across the phospholipid bilayer barrier.a-Sarcin, the best characterized member of the family of fungal ... inhibit protein synthesis and eventuallycause cell death [3,4], while the other is composed of certainmembers of the bovine pancreatic RNase A superfamily.Onconase, a homolog of RNase A from the ... membrane of t he target cell and enters it by endocytosis [6]. They u ndergo internalizationintrinsically, but their translocation across the plasmamembrane is the rate-limiting step of the...
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Báo cáo khoa học: A (1fi3)-b-D-glucan recognition protein from the sponge Suberites domuncula Mediated activation of fibrinogen-like protein and epidermal growth factor gene expression pot

Báo cáo khoa học: A (1fi3)-b-D-glucan recognition protein from the sponge Suberites domuncula Mediated activation of fibrinogen-like protein and epidermal growth factor gene expression pot

... al. (Eur. J. Biochem. 271) Ó FEBS 2004 of the sponge cell to the gene expression level and back to afurther molecule potentially involved in the recognition of the carbohydrate, the fibrinogen-like ... tridentatus[20] (AB024737.1 and AB024738.1), and the angiopoietinsfrom mammals, e.g. humans (O15123), form the secondbranch. The third branch is built by the ficolins, with the mouse ficolin B as an example ... (1fi3) -b- D-glucan-binding protein, which bindto (1fi3) -b- D-glucans, e.g. curdlan or laminarin. Afterbinding of the carbohydrate to the receptor, the expression of the gene coding for the binding protein...
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Tài liệu Báo cáo khoa học: Nuclear receptors in the mosquito Aedes aegypti Annotation, hormonal regulation and expression profiling ppt

Tài liệu Báo cáo khoa học: Nuclear receptors in the mosquito Aedes aegypti Annotation, hormonal regulation and expression profiling ppt

... FEBSAaHR305001000150020002500 b abaa b b b bAaHR403001000150020002500a b b b b b b b AaE7850100150200250300aaaaaaaa0100200AaEcR-A020406080100120 b a b b b b b b0 h 6 h 12 h ... (+SEM)AaUSP-A0102030405060a b b b b b b b AaUSP -B 0510152025aaaaaaaaAaE75A1 d 4 d 6 h 12 h 24 h 36 h 48 h 72 h040080012001600 b a b b b bab b PV PBM1 d 4 d 6 h 12 h 24 h 36 h 48 h 72 hPV PBMPVABPBMAaEcR -B 01234567aaaaaaaa0 ... ourlaboratory have been carried out to determine the role of AabFTZ-F1A in the acquisition of competence in the pre-vitellogenic fat body (i.e. the ability of the fatbodies to respond to 20E). By...
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Tài liệu Báo cáo khoa học: Tissue factor pathway inhibitor is highly susceptible to chymase-mediated proteolysis pptx

Tài liệu Báo cáo khoa học: Tissue factor pathway inhibitor is highly susceptible to chymase-mediated proteolysis pptx

... smeared bands (bands 1 and 2) with molecular masses of 20–30 kDa observed onSDS ⁄ PAGE. Subsequently, the level of the approxi-mately 15-kDa band increased, and TFPI (43 kDa) aswell as bands 1 and ... resi-dues. On the basis of these observations, we believethat the recombinant TFPI carried an O-linked carbo-hydrate chain on Thr14. Moreover, the peak heights and the areas under the peaks suggested ... are shown above the TFPI structure. The thick arrowsindicate the locations of the sites cleaved by chymase, whichinclude the amino acids and residue numbers. The open circles and branches indicate...
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Tài liệu Báo cáo khoa học: Platelet factor 4 disrupts the intracellular signalling cascade induced by vascular endothelial growth factor by both KDR dependent and independent mechanisms ppt

Tài liệu Báo cáo khoa học: Platelet factor 4 disrupts the intracellular signalling cascade induced by vascular endothelial growth factor by both KDR dependent and independent mechanisms ppt

... angiogenic factors, in cluding fibroblastgrowth factors (FGFs), platelet-derived growth factor < /b> B (PDGF -B) and vascular endothelial growth factor < /b> (VEGF)[1,2]. These factors are counterbalanced by inhibitorymolecules ... and compared the mechanisms bywhich PF-4 i nhibits the DNA synthesis induced byVEGF165 and VEGF121. The DNA synthesis induced by VEGF165 and VEGF121was strongly inhibited b y PF-4 (10 ... activation. The ability o f PF-4 to abolish the proliferation of endothelial cells induced by the two majorangiogenic growth factors s ecreted by tumours – VEGF and FGF2 – may be useful for the development...
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Tài liệu Báo cáo khoa học: Insulin/protein kinase B signalling pathway upregulates metastasis-related phenotypes and molecules in H7721 human hepatocarcinoma cell line pptx

Tài liệu Báo cáo khoa học: Insulin/protein kinase B signalling pathway upregulates metastasis-related phenotypes and molecules in H7721 human hepatocarcinoma cell line pptx

... expression of PKB was calculated by the intensityratio of PKB band and b- actin band.Assay of PKB activityPKB assay was performed with a widely used assay kit of Akt kinase according to the instruction ... added, and the incubationtime was extended to 36 h. Then the cells were fixed, stained and countered as described above, and the number of cellsthat had migrated to the lower side of the matrigel-coatedfilter ... of pBluescript-SK (2.96 kb) by T4 DNA ligase. The direction of the inserted PKB cDNA was determined byPstI digestion of the recombinant plasmid: there was a PstIsite near to the 5¢ end of the...
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Báo cáo khoa học: Nuclear actin and actin-binding proteins in the regulation of transcription and gene expression docx

Báo cáo khoa học: Nuclear actin and actin-binding proteins in the regulation of transcription and gene expression docx

... disruptsinteractions between the N- and C-termini of the AR, and interferes with the binding of the coactivator TIF2[86,91]. There is evidence that interaction between the FXXLF (X = any amino acid) motif of the ... actin and actin-binding proteins in the regulation of transcription and gene expressionBin Zheng1, Mei Han1, Michel Bernier2 and Jin-kun Wen11 Department of Biochemistry and Molecular Biology, ... com-plexes of the SWI ⁄ SNF family, such as those containing the ATPase subunits INO80 or SWR1 [15,24,39]. In the SWI ⁄ SNF-like BAF complex, b- actin binds directly to the BRG1 ATPase subunit of BAF and...
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