Báo cáo khoa học: Anti-amyloid precursor protein immunoglobulins inhibit amyloid-b production by steric hindrance ppt

... induced by isopropyl thio-b- D -galactoside and the overexpressed protein was finally purified by SP ion-exchange chromatography [24]. The purity of the protein was verified by SDS/PAGE. Protein concentration ... were of analytical grade. Purification of microtubular proteins (MTP), tubulin, MAP2, MAP2c and Tau proteins MTP was isolated from goat brain by two to four cycles of tempe...

Ngày tải lên: 23/03/2014, 12:20

... created by eliminating genome-length HCV RNA from the O cells by IFN treatment; and OR6c, cured cells which were created by eliminating genome-length HCV RNA from the cloned OR6 cells [44] by IFN ... analysis. Production of myc-TRIF in these cells was analyzed by immunoblotting as described in Fig. 6C. The black arrowhead indicates the noncleaved TRIF. Limited suppression of the I...

Ngày tải lên: 18/02/2014, 16:20

... a production& apos;s L2 con- stituent ordering as an orientation. It is sometimes useful to explicitly designate one of the two possible orienta- tions when writing productions. We do this by ... form where every production takes one of the followingforms: S ~ e/e S ~ A A ~ AA A ~ z/y A ~ ~:/e A ~ ely Proof By Lemmas 1, 2, and 3, we may assume T contains only productions of...

Ngày tải lên: 20/02/2014, 22:20

... rno-miR-326 by one nucleotide (italic) Differs from rno-miR-329 by four nucleotides (italic) Differs from rno-miR-330 by one nucleotide (italic) Table 1. New human microRNAs predicted by homology ... human orthologues of rat microRNA precursors described by Kim et al. [16] were localized in the human genome by BLAT on the UCSC Genome Browser server [54,57] or by examinati...

Ngày tải lên: 07/03/2014, 16:20

... 3-phosphoglycerate dehydrogenase (PGDH) catalyzes the first step in serine biosynthesis, and is allosterically inhibited by serine. Structural studies revealed a homotetramer in which the quaternary arrangement ... indicate residues 314 and 317 at the C-terminus of two of the NSD proteins. Residue 336,usedinboththeNSDandRBDproteins,isindicatedbythegreen Ca ball. 5 Ó FEBS 2002 D -3-Phosphogly...

Ngày tải lên: 17/03/2014, 11:20

... 167–178 ª 2010 The Authors Journal compilation ª 2010 FEBS Anti-amyloid precursor protein immunoglobulins inhibit amyloid-b production by steric hindrance Rhian S. Thomas 1 , J. Eryl Liddell 2 and Emma ... is cleaved from amyloid precursor protein (APP) [5]. APP can be processed by one of two proteolytic pathways. The Keywords Alzheimer’s disease; amyloid precursor...

Ngày tải lên: 29/03/2014, 00:20

... reactions can be modulated either by tight binding to proteins, establishing a functionally static RNA protein complex, or by transient interac- tions with proteins that dissociate from the RNA ... confor- mation is recognized by the protein, interacts with it to form a stable complex, and is thereby removed from the conformational equilibrium [23]. The second mechanistic class of pr...

Ngày tải lên: 14/02/2014, 19:20

... interaction) l MPK6 binds to PTI1-4 by pull down (View interaction) l PTI1-4 and MPK3 phosphorylate by protein kinase assay (View interaction) l OXI1 phosphorylates OXI1 by protein kinase assay (View ... HIS-OXI1 and GST-PTI1-4 proteins or HIS-PTI1-4 and GST-OXI1 proteins, the GST-tagged proteins were pulled down with glutathi- one-agarose beads. The proteins were then detected by...

Ngày tải lên: 14/02/2014, 19:20

... organization of HIV gag -protein shell in virus-like particles produced by recombinant baculovirus. Virol 198, 288–296. 9 Campbell S & Vogt VM (1995) Self-assembly in vitro of purified CA-NC proteins from ... assembly in vitro by inositol phos- phates. Proc Natl Acad Sci USA 98, 10875–10879. 12 Mayo K, Huseby D, McDermott J, Arvidson B, Finlay L & Barklis E (2003) Retrovirus capsi...

Ngày tải lên: 18/02/2014, 06:20

... architecture is the production of Gag and Gag- Pol fusion proteins. The GagPol fusion protein, formed by a ribosomal frame shift event, is cleaved into the Gag and Pol polypeptides by the viral protease. ... Author Journal compilation ª 2009 FEBS Gag polyprotein, yields the matrix protein (MA), the capsid protein (CA), the nucleocapsid protein (NC) and p6 proteins, as well as two...

Ngày tải lên: 18/02/2014, 06:20