Báo cáo khoa học: Novel suppression mechanism operating in e

Báo cáo khoa học: Novel suppression mechanism operating in early phase of adipogenesis by positive feedback loop for enhancement of cyclooxygenase-2 expression through prostaglandin F2a receptor mediated activation of MEK⁄ ERK-CREB cascade doc

... FEBS Novel suppression mechanism operating in early phase of adipogenesis by positive feedback loop for enhancement of cyclooxygenase-2 expression through prostaglandin F 2a receptor mediated activation ... mechanism operating in the early phase of adipogenesis through a positive feedback loop by enhancement of PGF 2a...

Ngày tải lên : 28/03/2014, 22:20

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Báo cáo khoa học: Novel dissociation mechanism of a polychaetous annelid extracellular haemoglobin pptx

... The in vivo association of such complex proteins remains unclear in polychaete annelids. The pathway of folding of HBL-Hbs has been reported to involve independent folding of indi- vidual domains, ... lipoprotein A (LDL-A) module] homologous to the cysteine-rich region of the ligand-binding domain of the low-den- sity-lipoprotein receptor (LDLR) family [30,31]. Stud- ies inv...

Ngày tải lên : 23/03/2014, 10:21

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Tài liệu Báo cáo khoa học: The calcium-induced switch in the troponin complex probed by ﬂuorescent mutants of troponin I doc

... Reinach, F.C. (1999) Regulatory properties of recombinant tropomyosins containing 5-hydroxytryptophan: Ca 2+ -binding to troponin results in a conformational change in a region of tropomyosin ... R.S. (1997) Mapping of a second actin-tropomyosin and a second troponin C binding sites within the C terminus of troponin I, and their importance in the Ca 2+ -dependent regulation of...

Ngày tải lên : 20/02/2014, 11:20

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Tài liệu Báo cáo khoa học: Novel aspects of heat shock factors: DNA recognition, chromatin modulation and gene expression ppt

... HSE-containing promoters by HSF2 is different from that of many active promoters, which are marked by binding of TATA-binding protein and recruitment of protein phosphatase 2A [67,68]. In mouse ... factor binding and gene expression [46]. Differences in the HSE-binding speciﬁcity are in part explained by the oligomerization of HSFs. When an amino acid substitution is m...

Ngày tải lên : 18/02/2014, 04:20

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Tài liệu Báo cáo khoa học: Limited suppression of the interferon-b production by hepatitis C virus serine protease in cultured human hepatocytes pptx

... 2; RIG-I, retinoic acid-inducible gene I; siRNA, small interfering RNA; TBK, Tank-binding kinase 1; TLR, Toll-like receptor; TRIF, Toll-IL1 receptor domain-containing adaptor inducing IFN-b. FEBS ... components, including DNA, ssRNA, dsRNA and glycoproteins. This response initiates signaling pathways leading to the induction of protective cellular genes, including type-I interferons [ini...

Ngày tải lên : 18/02/2014, 16:20

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Tài liệu Báo cáo khoa học: On the mechanism of action of the antifungal agent propionate Propionyl-CoA inhibits glucose metabolism in Aspergillus nidulans doc

... oxidation of acetate is not inhibited by propionate. Therefore, we searched for an alternative reaction converting succinyl-CoA into succinate. For this purpose we determined the ability of cell-free ... of 2 lmol NADPÆmin )1 Æmg protein )1 . Determination of maintenance In order to calculate the amount of glucose used for maintenance, the wild-type strain A26 was used. Fo...

Ngày tải lên : 19/02/2014, 16:20

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Tài liệu Báo cáo khoa học: Novel aggregate formation of a frame-shift mutant protein of tissue-nonspeciﬁc alkaline phosphatase is ascribed to three cysteine residues in the C-terminal extension pdf

... oligosaccharide chains of glycoproteins [31]. The involvement of EDEM and ⁄ or SCF Fbs2 in the degrada- tion of TNSALP mutant proteins is currently being investigated. The aggregate form of TNSALP (1559delT) possesses ... cells were preincubated for 0.5–1 h in the methionine ⁄ cysteine-free DMEM and labeled with 50–100 lCi of [ 35 S]methionine ⁄ cysteine for 0.5 h in the f...

Ngày tải lên : 19/02/2014, 17:20

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Tài liệu Báo cáo khoa học: "A COMPUTATIONAL MECHANISM FOR PRONOMINAL REFERENCE" pot

... handling cases of backwards pronominalization, as in (18). (18) [His] mother loves [John], Clause [I.C] handles backwards pronominalization by making use of information in °table -of- proforms*, ... antecedents in one traversal and checked for minimality during a second. Since update-node is a general mechanism for adding or modifying information to a node on the bas...

Ngày tải lên : 21/02/2014, 20:20

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Báo cáo khoa học: The catalytic mechanism of dye-decolorizing peroxidase DyP may require the swinging movement of an aspartic acid residue potx

... the heme-distal side by passing through the cavity, and then bind and react (with heme) within the pocket (Fig. 2B). Conservation of residues forming the binding pocket for H 2 O 2 Primary sequence ... occupied by OD2 in D171N-CN, and that OD2 can swing from the position occupied in the native to the position seen in D171N-CN, we propose a swing mechanism for the formation...

Ngày tải lên : 06/03/2014, 00:20

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Báo cáo khoa học: Novel repressor of the human FMR1 gene ) identiﬁcation ¨ of p56 human (GCC)n-binding protein as a Kruppel-like transcription factor ZF5 ppt

... pairs of primers, which amplify overlapping 5¢- and 3¢-parts of ZF5 cDNA, were designed using Primer software developed by V. Prutkovsky and O. Sokur of the Institute of In uenza, Ministry of Health of ... pGEXZF5 encoding recombinant fusion protein, which consists of glutathione S-transferase (N-terminal part) and the DNA-binding domain of ZF5 (C-terminal part), was kindly...

Ngày tải lên : 07/03/2014, 05:20

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