... threedomain E3-binding protein (E3BP, Fig. 1) also has ananchoring C-terminal domain, an E3-binding domain and amobile lipoyl domain. Again, the lipoyl domain contributesas a substrate and intermediate ... subunitdomains: L1, N-terminal lipoyl domain; L2, inner lipoyl domain; B, E1binding domain; I, oligomer-forming, acetyl-transferase-catalyzinginner domain. E3BP domains: L3, N-terminal lipoyl domain; ... domain; B, E3binding domain; I, inner domain which associates with the innerdomain of E2. Dotted connections indicate binding interactions to thecatalytic components (E1 and E3), kinase isoforms...