Báo cáo Y học: Suppression of apolipoprotein C-II amyloid fo

Báo cáo Y học: Suppression of apolipoprotein C-II amyloid formation by the extracellular chaperone, clusterin potx

... to the inhibition observed at the higher concentrations of apoC-II. Amyloid ﬁbril size is reduced by the presence of clusterin The effect of clusterin on the aggregation-state of apoC-II amyloid ... an inhibitory effect of clusterin on amyloid formation by Ab, and a fragment of the prion protein [26,27]. In this investigation, we explore the effect...

Ngày tải lên : 24/03/2014, 04:21

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Báo cáo y học: "Effect of corticosteroids on phlebitis induced by intravenous infusion of antineoplastic agents in rabbits"

... induced by intravenous infusion of antineoplastic agents re- duces the completion of chemotherapy. The causative factors of phlebitis include the pH and osmotic pres- sure of the solution, the size ... histopathologically. The effect of DEX on VNR-induced phlebitis was evaluated by infusion of DEX before or after VNR. The effect of PSL on DXR-induced phlebit...

Ngày tải lên : 26/10/2012, 09:57

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Tài liệu Báo cáo Y học: Inhibition of nuclear pre-mRNA splicing by antibiotics in vitro pot

... into the splicing-compatible tertiary structure by the charged groups of these antibiotics. The macrolide, erythromycin, the strongest inhibitor, had only a slight eect on formation o f the presplicing ... in inhibition of spliceosome assembly. Formation of the presplicing complexes A and B was slightly reduced by increasing concentrations of erythromycin (lanes 5...

Ngày tải lên : 21/02/2014, 15:20

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Tài liệu Báo cáo Y học: Induction of (2¢)5¢)oligoadenylate synthetase in the marine sponges Suberites domuncula and Geodia cydonium by the bacterial endotoxin lipopolysaccharide docx

... identiﬁed by thin-layer chromatography, immunologically and by high-performance liquid chromatography. The biological activity of (2–5)A oligo- mers was veriﬁed by inhibition of the protein synthesis ... the (2–5)A pathway is also induced by interferons [15]. The major enzyme in this pathway, the (2–5)A synthetase catalyzes the synthesis of a series of 2¢)5¢- lin...

Ngày tải lên : 21/02/2014, 15:20

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Tài liệu Báo cáo Y học: Toxicity of substrate-bound amyloid peptides on vascular smooth muscle cells is enhanced by homocysteine docx

... University of Heidelberg, Heidelberg, Germany; 4 The School of Chemistry, The University of Melbourne, Parkville, Victoria, Australia The main component of cerebral amyloid angiopathy (CAA) in ... aggregationwasshowntocorrelatewith the toxic response in the VSMC. The duration of the Ab ageing by incubation at 37 °C was related to the amount of lactate dehydroge...

Ngày tải lên : 22/02/2014, 07:20

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Báo cáo Y học: Mechanism of 1,4-dehydrogenation catalyzed by a fatty acid (1,4)-desaturase of Calendula ofﬁcinalis pptx

... were prepared by routes which were very similar to those reported previously for the synthesis of the corres- ponding chiral monodeutero analogues [27]. Thus, the tosylate of 8-hydroxy-[8,8 2 H 2 ]octanoic ... (10 mL) of the S. cerevisiae transformant (pYJ/DTY10-a2) using conditions identical to that of the trial experiment. The deuterium content of the oleﬁnic fatty...

Ngày tải lên : 08/03/2014, 09:20

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Báo cáo Y học: Binding of Thermomyces (Humicola) lanuginosa lipase to the mixed micelles of cis-parinaric acid/NaTDC Fluorescence resonance energy transfer and crystallographic study ppt

... revealed by TLL-OA complex crystal structure. (A) Anti sn-1 position of the OA in the hydrophobic catalytic cleft of the open conformation of TLL(S146A). The REFMAC 2Fo-Fc electron density map of the ... ﬂexibility f or the putative ligand in the active site region. This relaxation, together with the lack of steric h indrance created usually by the hydroxyl g r...

Ngày tải lên : 08/03/2014, 23:20

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Báo cáo Y học: Effect of coenzymes and thyroid hormones on the dual activities of Xenopus cytosolic thyroid-hormone-binding protein (xCTBP) with aldehyde dehydrogenase activity potx

... On the other hand, the ALDH activity was inhibited by NADH, NADPH, disulﬁram, iodothyronines and Triac, but not by any of the steroids tested. We initially expected xCTBP/ xALDH1 to be one of the ... shown). Thus, the second possibility is unlikely to occur in xCTBP/xALDH1. There are many reports of the inhibitory effects of thyroid hormones upon the activity of se...

Ngày tải lên : 31/03/2014, 21:21

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Báo cáo Y học: Ruk is ubiquitinated but not degraded by the proteasome ppt

... were lysed and the quantity of protein measured by Bradford assay. 10 lg of total protein from each cell lysate was separated by SDS/PAGE. The level of exogenous EE-Ruk L was determined by Western ... recognized by the 26S proteasome or, in certain cases, by the lysosomes/vacuole and rapidly degraded. Ubiquitination of target proteins involves a cascade of reaction...

Ngày tải lên : 17/03/2014, 23:20

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Báo cáo y học: " Implementation of a new emergency medical communication centre organization in Finland an evaluation, with performance indicators"

... However, the assessment of the outcome of the money spent to finance the EMS is generally not evidence-based [4]. A lack of structured evaluations of organizational changes in the EMCC is evident. The ... highest priority to 7.4 percent of the calls compared to 3.6 percent in the old system. The high priority cases not detected by dispatchers increased significan...

Ngày tải lên : 25/10/2012, 10:02

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