... CTGF/Hcs24 induces chondrocyte differentiation through a p38 mitogen-activated protein kinase (p38MAPK), and proliferation through a p44/42 MAPK/extracellular-signal regulated kinase (ERK) Gen ... investigated the effects of MAP kinase inhibitors on pathways of proliferation by analyzing DNAsynthesis, and pathways of differentiation by analyzingproteoglycan synthesis, in HCS-2/8 and RGC ... (ERK) Gen Yosimichi1,2, Tohru Nakanishi1, Takashi Nishida1,3, Takako Hattori1, Teruko Takano-Yamamoto2 and Masaharu Takigawa1,31Department of Biochemistry and Molecular Dentistry, and 2Department...