Báo cáo Y học: Fusion of farnesyldiphosphate synthase and epi-aristolochene synthase, a sesquiterpene cyclase involved in capsidiol biosynthesis in Nicotiana tabacum docx

... or Dynasan™ 118 along with soyalecithin as the lipid parts. Different formulation parameters; including type of Dynasan, soyalicithin:Dynasan ratio, drug:total lipid ratio, and polyvinyl al-cohol ... Yassin AE, Alsarra IA, Alanazi FK, et al. New targeted-colon delivery system: in vitro and in vivo evaluation using x-ray imaging. J Drug Target. 2010; 18: 59-66. 31. Alanazi FK, Yassin A, El-Badry ... Yassin1,2, Md. Khalid Anwer3, Hammam A. Mowafy1, Ibrahim M. El-Bagory1, Mohsen A. Bayomi1,2 and Ibrahim A. Alsarra1,2,  1. Department of Pharmaceutics, College of Pharmacy, King...

... RNA level, profound hyperbilirubinemia and high levels of alkaline phosphatase and gamma-glutamyl transferase, and liver biopsy reveals feathery degeneration predominantly in the perivenular ... small single center trials in patients treating established recurrent HCV using the combination of pegylated interferon alpha-2b and ribavirin have resulted in end -of- treatment and sustained ... hepatocellular function improves and in turn leads to rejection. There have been increasing reports of pegylated interferon and ribavirin therapy possibly increasing the rates of both acute cellular and...

... targetsspanning 114 bp was impaired. This impediment wasmaintained over at least 72 h and was not affected by thetranscriptional status of chromatin nor by inhibitors of histonedeacetylases and ... promoter was enhanced several-fold byboth types of inhibitors. Apparently an opening of thechromatin structure through hyperacetylation of histones and possible changes in DNA and/ or chromatin topologyresulting ... histonedeacetylases or topoisomerasesHistone modifications such as acetylation and phosphoryl-ation play important roles in the regulation of chromatinstructure. In particular acetylation of the...

... deuterium labelling; Calendula.The D12-oleate desaturase (FAD2) family of enzymes aremembrane-bound nonheme iron-containing proteins thatcarry out a fascinating array of related oxidative transfor-mations ... linoleate and regiospecificallydideuterated isotopomers with a strain of Saccharomycescerevisiae expressing a functional (1,4)-desaturase. GC-MSanalysis of methyl calendate obtained in these ... Covello11Plant Biotechnology Institute, Saskatoon, SK, Canada;2Department of Chemistry, Carleton University, Ottawa, Ontario, CanadaThe mechanism by which the fatty acid (1,4)-desaturase of Calendula...

... that cyclosporin A (CsA), vinblastine, and valinomycin (and several otherdrugs; N. Nagy, K. Goda, F. Fenyvesi & G. Szabo´Jr,unpublished data)1interactwithPgpinsuchamannerthatpreincubation ... Walker, J.E., Saraste, M., Runswick, M.J. & Gay, N.J. (1982)Distantly related sequences in the alpha- and beta-subunits of ATP synthase, myosin, kinases and other ATP requiring enzymes and ... thechemicals applied increased steady-state daunorubicinaccumulation to the approximate level reached in Pgp–parental cells and did not significantly increase the ratio of dead cells, as assessed by...