Báo cáo Y học: Substrate selectivity and sensitivity to inhibition by FK506 and cyclosporin A of calcineurin heterodimers composed of the a or b catalytic subunit potx
Báo cáo Y học: Substrate selectivity and sensitivity to inhibition by FK506 and cyclosporin A of calcineurin heterodimers composed of the a or b catalytic subunit potx
... state, the < /b> CaN autoinhibitory domain lies over the < /b> catalytic site [20]. The < /b> amino-acid sequences of < /b> the < /b> CnAa and < /b> CnAb catalytic domains are 90% identical, and < /b> the < /b> autoinhibitory domain amino-acid ... substrates, the < /b> phosphatase activities of < /b> CaNa and < /b> CaNb are only 70%, and < /b> 50% inhibited by < /b> 90 l M C...
Ngày tải lên: 24/03/2014, 03:21
Báo cáo khoa học: Caspase-2 is resistant to inhibition by inhibitor of apoptosis proteins (IAPs) and can activate caspase-7 pot
... caspase-2 activity than the < /b> yeast death assay. Caspase-2 is not inhibited by < /b> mammalian IAP proteins Members of < /b> the < /b> mammalian IAP family contribute to < /b> the < /b> regulation of < /b> apoptotic pathways in part ... activation of < /b> caspase-7. Caspase-2 was not subject to < /b> inhibition < /b> by < /b> members of < /b> the < /b> IAP family of < /b> a...
Ngày tải lên: 23/03/2014, 13:20
Báo cáo y học: "Relationships between free radical levels during carotid endarterectomy and markers of arteriosclerotic disease"
... the < /b> samples treated with an antioxidant cocktail from that of < /b> the < /b> saline samples yields the < /b> part of < /b> the < /b> signal that can be attributed to < /b> superoxide and/< /b> or < /b> hydroxyl radicals or < /b> any secondary ... via the < /b> facial vein into the < /b> jugular vein and < /b> advanced up to < /b> the < /b> level above the < /b> sku...
Ngày tải lên: 26/10/2012, 10:03
Tài liệu Báo cáo Y học: Studies into factors contributing to substrate specificity of membrane-bound 3-ketoacyl-CoA synthases pot
... 5¢-GCGCTCGAAAATCTATTCAAGAACACC-3¢ At173anti 5¢-GTTCTTGAATAGATTTTCGAGCGCACCGATGATAAC-3¢ Bn173sense 5¢-GCCCTAGAAAATCTATTCAAGAACACC-3¢ Bn173anti 5¢-GTTCTTGAATAGATTTTCTAGCGCACCATT-3¢ At399sense 5¢-GCCGGAGGCAGAGCCGTGATCGAT-3¢ At399anti ... was measured by < /b> incubation with malonyl CoA and < /b> required cofactors, followed by < /b> transacylation of < /b> the < /b> CoA conjugates to < /b...
Ngày tải lên: 21/02/2014, 15:20
Tài liệu Báo cáo Y học: Transactivation domains are not functionally conserved between vertebrate and invertebrate serum response factors potx
... GATA-4 [16] or < /b> myocardin [17] transcription factors. Other cofactors are regulated by < /b> growth-factor transduction pathways, such as the < /b> classical ternary complex factors, that are activated by < /b> MAP-kinase ... 2002 TCTTATATGAATGCAGTTCTG-3¢;N3:5¢-GGGAAT TCGCTAGGCCACAGTTTGAATTTG-3¢;N4:5¢-GGG AATTCGACCTCTGAAAATGTAAAACAG-3¢;N5: 5¢-GGGAATTCGGATCCTCTAACTGGGTTAGAT-3¢; N6: 5...
Ngày tải lên: 22/02/2014, 07:20
Báo cáo Y học: Variations in receptor site-3 on rat brain and insect sodium channels highlighted by binding of a funnel-web spider d-atracotoxin pdf
... association rate. The < /b> binding of < /b> 125 I-labelled d-ACTX-Hv 1a < /b> to < /b> rat brain syna- ptosomes is inhibited c ompetitively by < /b> classical ScaTxs and < /b> allosterically by < /b> brevetoxin-1, similar to < /b> ScaTx binding. However, ... E-mail: dgordon@post.tau.ac.il Abbreviations: Aah-II, antimammalian a-< /b> toxin II from the < /b> venom of < /b> the < /b...
Ngày tải lên: 08/03/2014, 16:20
Báo cáo Y học: Monoterpene biosynthesis in lemon (Citrus limon) cDNA isolation and functional analysis of four monoterpene synthases pot
... GC-MS as described above and < /b> on a < /b> radio-GC consisting of < /b> a < /b> Carlo-Erba 4160 Series gas chromatograph (Carlo-Erba, Milano, Italy) equipped with a < /b> RAGA-90 radioactivity detector (Raytest, Straubenhardt, ... primer for B9 3 contained a < /b> PstI restriction site 5¢-GCCAACTGCAGAATGAGGCGATCTGCCGATT ACG-3¢. The < /b> sense primer for C62 and < /b> M34 was 5¢-G...
Ngày tải lên: 08/03/2014, 23:20
Báo cáo Y học: Boar salivary lipocalin Three-dimensional X-ray structure and androstenol/androstenone docking simulations pot
... Universite ´ di Pisa, Italy The < /b> X-ray structure of < /b> variant A < /b> of < /b> authentic boar salivary lipocalin (SAL), a < /b> pheromone-binding protein specifically expressed in the < /b> submaxillary glands of < /b> the < /b> boar, has been solved ... excreted, they are strongly associated with specific sex pheromones. Proteins similar to < /b> the < /b> urinary proteins...
Ngày tải lên: 17/03/2014, 17:20
Báo cáo Y học: Nuclear proteins that bind to metal response element a (MREa) in the Wilson disease gene promoter are Ku autoantigens and the Ku-80 subunit is necessary for basal transcription of the WD gene ppt
... polyacrylamide) followed by < /b> electrotransfer to < /b> a < /b> nitrocellulose membrane. Blots were incubated with a < /b> 32 P end-labelled MREa probe as described in Materials and < /b> methods and < /b> subjected to < /b> autoradiography. ... extracts from HepG2 for 5 min and < /b> then incubated for an additional 30 min either in the < /b> absence (lane 1) or < /b> presence...
Ngày tải lên: 17/03/2014, 23:20
Báo cáo Y học: DNA supercoiling in Escherichia coli is under tight and subtle homeostatic control, involving gene-expression and metabolic regulation of both topoisomerase I and DNA gyrase docx
... and < /b> that the < /b> pA1lacO-1 promoter and < /b> the < /b> lacI q1 gene are surrounded by < /b> a < /b> DNA fragment originating from upstream the < /b> gyrA gene and < /b> a < /b> fragment containing the < /b> N-terminal part of < /b> the < /b> gyrA gene. To < /b> ... to < /b> nitrocellulose and < /b> Ponceau staining [Ponceau-S, 0.2% in 3% trichlororacetic acid (Serva)]...
Ngày tải lên: 18/03/2014, 01:20