... Dietary bisphenol A prevents ovarian degeneration and bone loss in female mice lacking the aromatase gene (Cyp19 ) Katsumi Toda1, Chisato Miyaura2, Teruhiko Okada3 and Yutaka Shizuta11Department ... Toda, K., Takeda, K., Okada, T., Akira, S., Saibara, T., Kaname,T., Yamamura, K., Onishi, S. & Shizuta, Y. (200 1) Targeteddisruption of the aromatase P450 gene (Cyp1 9) in mice and their ovarian ... fromOriental Yeast (Tokyo, Japan). BPA and E2 were fromSigma-Aldrich. An ELISA kit for BPA was from TakedaPharmaceutical Co. Ltd. (Tokyo, Japan). All other chem-icals were of analytical grade.AnimalsAnimal...