Báo cáo Y học: Soluble guanylate cyclase is allosterically inhibited by direct interaction with 2-substituted adenine nucleotides doc

... nucleotides is a general characteristic of the family of guanylate cyclases. This allosteric inhibition is mediated by direct interaction of adenine nucleotides with sGC, likely at the catalytic ... Soluble guanylate cyclase is allosterically inhibited by direct interaction with 2-substituted adenine nucleotides Inez Ruiz-Stewart, Shiva Kazerounia...

Ngày tải lên: 24/03/2014, 03:21

... status, homocysteine metabolism, and methylene tetrahydrofolate reductase genotype in rural South African blacks with a history of pregnancy complicated by neural tube defects. Metabolism. 1999;48(2):269-74. ... synthase, which uses 5-methyltetrahydrofolate as a carbon donor [6] . This donor is synthesized by the methylenetetrahydrofolate reductase (MTHFR) gene from 5,10-methylene...

Ngày tải lên: 03/11/2012, 09:49

... jelly like substance within the shells of cultured Crassostrea gigas is frequently reported by farmers. This phenomenon is usually accompanied by a thickening of the shell, with spaces filled by ... samples by increasing the aliquot size, as proposed by Gold [30]. Calcium analysis Calcium analyses were performed after nitric acid hydrolysis of samples, by atomic absorption sp...

Ngày tải lên: 21/02/2014, 01:21

... the notion that antizyme may be degraded together with ODC, they suggest that interaction with ODC is not essential f or the degradation of antizyme. This conclusion is supported mainly by the experiment ... llular polyamines c omes from t heir synthesis from amino acid precursors. In this biosynthesis pathway ornithine is decarboxylated to form putrescine by the action of orn...

Ngày tải lên: 22/02/2014, 04:20

... activity is critical for C 2 -ceramide-induced apoptosis in PC12 cells Mutsuya Yamamoto, Takeshi Hioki, Takehisa Ishii, Sadayo Nakajima-Iijima and Shigeo Uchino* Pharmaceuticals Discovery Laboratory, ... apoptosis and necrosis. However, it is not known whether the k inase activity is involved in apoptosis. In the present study, we employed PC12 cells, extensively used as a model to stud...

Ngày tải lên: 24/03/2014, 00:21

... p53, which is phosphorylated by cyclin A/cdk2 [16]. Site-directed mutagenesis procedures and the two-dimensional peptide mapping analysis have established that Ser274 in p70 ik3-1 is phosphorylated by ... resembles the site in p53 which is phosphorylated by cyclin A/cdk2 [16]. We therefore asked whether this position is the phosphorylated Fig. 3. p70 ik3-1 is phosphorylated b...

Ngày tải lên: 24/03/2014, 04:21

... Mus, Turkey 4. Yuzuncu Yil University Faculty of Science, Department of Chemistry, Van, Turkey 5. Yuzuncu Yil University, Faculty of Medicine, Department of Cardiology, Van, Turkey  Corresponding ... may be increased in patients with CAD. Key words: coronary artery disease; trace element; heavy metal; vitamin INTRODUCTION Coronary artery disease (CAD) is a leading cause of morbid...

Ngày tải lên: 25/10/2012, 10:51

... common risk factor for uterine rupture is a history of Cesarean section. Other risk factors in- clude placenta previa; high parity; advanced maternal age; and a history of endometriosis, dilatation ... decidua basalis is partially or completely absent, and the chorionic villi invade the entire myometrium up to the serosa [5]. Uterine rupture caused by placenta percreta mainly occur...

Ngày tải lên: 25/10/2012, 10:56

... and Surgery, University of Bari, Bari, Italy 2. Department of Medical Biochemistry, Medical Biology and Physics, University of Bari, Bari, Italy 3. Department of “Head and Neck Surgery”, Hospital ... anomaly characterized by an excess in tooth number. It seems to occur more often in patients with hereditary factors concerning this anomaly: this case represents a rare form of hyperdont...

Ngày tải lên: 25/10/2012, 11:40