Báo cáo Y học: Novel regulatory regions found downstream of the rat B29/Ig-b gene docx
Báo cáo Y học: Novel regulatory regions found downstream of the rat B29/Ig-b gene docx
... activity than e ach of the three regions individually, the +4.4a to +6.5d regions along with +8.7e s hould be involved in B29/Ig-b gene expression. Neither the 2.9-kb DNA nor any of the three regions ... or downstream in the gene [21,22] as well as in pro moter regions. In this study, cell type-specific DHS in and around the B29/Ig-b gene were used as landmar...
Ngày tải lên: 24/03/2014, 03:21
Báo cáo Y học: Cloning, chromosomal localization and characterization of the murine mucin gene orthologous to human MUC4 pdf
... studied but their analysis showed that they did not contain the central region or the 5¢ end of the gene. The cosmid clone containing the longest part of the new gene was named CAR1 and studied. The ... sequence of the 3¢ part of the gene encompassing 17 kb. Three poly(A) signals were found after the stop codon. Analysis of the four cosmid clones by PCR...
Ngày tải lên: 08/03/2014, 23:20
Báo cáo Y học: Novel fish hypothalamic neuropeptide Cloning of a cDNA encoding the precursor polypeptide and identification and localization of the mature peptide pptx
... as one of the bovine RFRPs [15]. Collectively, these peptides identified from the brain of several vertebrates are characterized by the LPXRF-NH 2 motif at their C-termini. The presence of novel ... accord- ance with the Guide for the Care and Use of Laboratory Animals prepared by Hiroshima University, Japan. Total RNA of the diencephalon was extracted by the guanid...
Ngày tải lên: 08/03/2014, 16:20
Báo cáo Y học: ATP stimulates MDM2-mediated inhibition of the DNA-binding function of E2F1 pot
... system to analyse the molecular chaperone function of MDM2 on another of its tar- get proteins, the transcription factor E2F1. In the absence of ATP, MDM2 was able to catalyse inhibition of the ... chap- erone activity and directly mediate folding of the p53 tetramer. Analysing the ATP-dependent function of MDM2 will provide novel insights into the evolution and fu...
Ngày tải lên: 24/03/2014, 00:21
Tài liệu Báo cáo khoa học: Helix mobility and recognition function of the rat thyroid transcription factor 1 homeodomain – hints from 15N-NMR relaxation studies pdf
... 1.79 ns by RSDM calculation. The homogeneity of the values of the overall correlation time calculated from the individual (R 2 ⁄ R 1 ) ratios suggested a good degree of isotropy of the global ... inertia. In the context of RSDM, the detailed analysis of the three spectral densities J(0), J(x N ) and J(0.87x H ) allowed us to obtain a rather complete description of...
Ngày tải lên: 18/02/2014, 16:20
Tài liệu Báo cáo Y học: Novel bradykinins and their precursor cDNAs from European yellow-bellied toad (Bombina variegata) skin potx
... m/z ratios. This sensitivity is well within the capability of the ES-MS system employed. The primary structural diversity displayed within amphibian skin bradykinins may not simply be due to phylogenetic ... standardization of each synthetic peptide was achieved by acid hydrolysis of a known gravimetric quantity of lyophilisate followed by amino acid analysis using an Applied Bi...
Ngày tải lên: 21/02/2014, 15:20
Tài liệu Báo cáo Y học: Novel complexes of mammalian translation elongation factor eEF1AÆGDP with uncharged tRNA and aminoacyl-tRNA synthetase potx
... amino- acylation. Here we present the data on association of the [eEF1AÆGDPÆtRNA] complex with phenylalanyl-tRNA synthetase (PheRS), e.g. the formation of the above quaternary complex detected by the ... that the complex of eEF1A, eEF1Ba and nonhydrolyzable analog of GTP could be dissociated by aminoacyl-tRNA rather than by deacylated tRNA [37] favors the decrease in affi...
Ngày tải lên: 21/02/2014, 15:20
Tài liệu Báo cáo Y học: Interallelic recombination is probably responsible for the occurrence of a new as1-casein variant found in the goat species potx
... mainly described and intensively investigated as mechanisms generating allelic diversity in highly polymorphic genetic systems, such as the loci encoding the class-II cell surface antigens of the ... explaining the hetero- geneity of phosphorylation observed for the n ative protein by ES/MS analysis (Fig. 4). Finally, peptide E96QLLR100, diagnostic of the F v ariant, was pre...
Ngày tải lên: 22/02/2014, 04:20
Báo cáo Y học: Novel protein phosphatases in yeast docx
... that deletion of PPZ1 partially rescued the growth defect of a sit4 mutant, thus mimicking the effect of overexpression of HAL3.Furthermore,lackofPPZ1 suppressed the s ynthetic lethality of the sit4 ... eletion of the PPG1 gene yields v iable cells whose only known phenotype is a decrease in glycogen accumulation [47]. The state of activation of glycogen synthase...
Ngày tải lên: 17/03/2014, 23:20
Báo cáo y học: "Eosinopenia is a reliable marker of sepsis on admission to medical intensive care units"
... in the acquisi- tion of data. AZ participated in the coordination of the study. AAZ participated in the design of the study, and performed the statistical analysis. RA conceived of the study, ... early diagnosis of sepsis before receiv- ing the results of microbial culture would certainly facilitate the choice of antibiotic therapy and reduce the patient mort...
Ngày tải lên: 25/10/2012, 10:35