Báo cáo Y học: Proteolytic action of duodenase is required to induce DNA synthesis in pulmonary artery fibroblasts A role for phosphoinositide 3-kinase pot
... 2002 Proteolytic action of duodenase is required to induce DNA synthesis in pulmonary artery fibroblasts A role for phosphoinositide 3-kinase Alan D. Pemberton 1 , Tatyana S. Zamolodchikova 2 , ... we have investigated the ability of duodenase to induce DNA synthesis in bovine pulmonary artery fibroblasts, attempting to elucidate wh...
Ngày tải lên: 24/03/2014, 03:21
... c-Cbl-associating protein; FRAP/ mTOR, mammalian target of rapamycin; MAP, mitogen activa ted protein ; MAPK, MAP kinase, MEK, MAP/ERK kinase; PI3- kinase, phosphatidylinositol 3-kinase; PKB/ Akt, ... to serine (CfiS) or an aspartate to alanine (D A) within the catalytic domain of Fig. 1. Scheme of the major insulin signaling pathways. The activated insulin receptor phosphorylates t...
Ngày tải lên: 17/03/2014, 23:20
... University of Calgary, Calgary, AB T2N 2T9, Canada 3 Department of Medicine, University of Calgary, Calgary, AB T2N 2T9, Canada 4 Alberta Kidney Disease Network, Calgary, AB T2N 2T9, Canada 5 Calgary ... appear to vary according to patient characteris- tics. Finally, ICU-acquired hyponatraemia and hypernatraemia are associated with increased in- hospital mortality. Studies are need...
Ngày tải lên: 25/10/2012, 10:31
Báo cáo y học: " Eradication rate of Helicobacter pylori according to genotypes of CYP2C19, IL-1B, and TNF"
... Research Paper Eradication rate of Helicobacter pylori according to genotypes of CYP2C19, IL-1B, and TNF -A Yoshiko Ishida, Yasuyuki Goto, Takaaki Kondo, Mio Kurata, Kazuko Nishio, Sayo Kawai, Tomo ... previously [23]. Statistical analysis Statistical analysis was performed using STATA Ver. 8 (College Station, TX) statistical software. The Hardy-Weinberg equilibrium, which indi...
Ngày tải lên: 31/10/2012, 16:57
Tài liệu Báo cáo Y học: The binding of lamin B receptor to chromatin is regulated by phosphorylation in the RS region ppt
... Instrumental Analysis, Niigata University, Japan Binding of lamin B receptor (LBR) to chromatin was studie d by means o f an in vitro assay system involving recombinant fragments of human LBR and Xenopus ... GST–NK beads at 23 °C. with a synthetic phase cytosol fraction was examined a nd it was found that 60 min is necessary to reach a plateau of increased binding affinity...
Ngày tải lên: 22/02/2014, 04:20
Tài liệu Báo cáo Y học: Structural determinants of the half-life and cleavage site preference in the autolytic inactivation of chymotrypsin pdf
... were performed to test the role of cleavages in the interdomain and autolysis loops in the inactivation of chymotrypsin. At first, D-chymo- trypsin and the interdomain and autolysis loop mutants ... mutagenesis of autolytic sites Phe114, Tyr146 and Asn147 on the processes of autolysis and autolytic inactivation. MATERIALS AND METHODS Enzymes For practical reasons, instead of...
Ngày tải lên: 22/02/2014, 07:20
Báo cáo Y học: Solution structure of the Alzheimer amyloid b-peptide (1–42) in an apolar microenvironment Similarity with a virus fusion domain potx
... analysis using a Hewlett Packard G202 5A LD-TOF system mass spectro- meter and a- cyano-4-hydroxycinnamic acid as matrix. Sample preparation It has been shown that a trifluoroacetic acid pretreatment renders ... C-terminal moiety, with those of the fusion domain of in uenza hemagglutinin suggests a direct mechanism of neurotoxicity. Keywords: Alzheimer disease; amyloid peptides;...
Ngày tải lên: 08/03/2014, 09:20
Báo cáo Y học: The effect of amino-acid substitutions I112P, D147E and K152N in CYP11B2 on the catalytic activities of the enzyme pdf
... diseases, Fig.3.Assessmentof11b-h ydroxylase a ctivity and determination of 11b-hydroxylase capacity. (A) Assessmentof11b-hydroxylase activity of CYP11B2 var iants e xpressed i n COS-1 cells. Cells were cotrans- fected ... duplicate. (B) Determination of 11b-hydroxylase capacity of CYP11B2 mutants in relation to the wild-type enzyme, when incubated with 11-deoxycortisol. The 11b...
Ngày tải lên: 24/03/2014, 03:21
Báo cáo y học: "The epidemiology of medical emergency contacts outside hospitals in Norway - a prospective population based study"
... necessary NACA 4 Development of vital (life threatening) danger possible NACA 5 Acute vital (life threatening) danger NACA 6 Acute cardiac or respiratory arrest NACA 7 Death Zakariassen et al. Scandinavian ... mission” ,A0 6“Inconclusive pro- blem” ,A1 0“Chest pain” and A3 4 /A3 5 “Accidents”)and one category containing the rest, called “All Other” in the analyses. In the analysis of...
Ngày tải lên: 25/10/2012, 09:56
Báo cáo y học: "Excess circulating angiopoietin-2 is a strong predictor of mortality in critically ill medical patients"
... indicating a role for Ang-2 as a mediator in critically illness, the value of Ang-2 as a predictive marker of outcome is poorly defined. The aim of this study was to investigate the independent value of ... non-redundant mediator of endothelial activation in experimental sepsis. Binding of circulating Ang-1 to the Tie2 receptor protects the vasculature from inf...
Ngày tải lên: 25/10/2012, 10:31