Báo cáo khoa học: "THE INTONATIONAL STRUCTURING OF DISCOURSE" pdf

... or deaccenting of particular lexical items? With choice of tune? More generally, we also characterize the contributions of these intonational phenomena in terms of the theory .of, discourse ... In particular, how much intonational structuring of generated text can be done automatically? What sorts of information must be represented to support the assignment of rhetor...

Ngày tải lên: 24/03/2014, 02:20

... performance of a bronchoalveolar lavage for culture, or start of or a change in antimicrobial therapy in case of unex- pected infiltrates on the CXR; repositioning of tubes in case of malposition of orotracheal ... ultrasound of the thorax in case of pleural effusion on the CXR, start or change in medication (diuretics); insertion of a pleural drain; and repositioning of d...

Ngày tải lên: 25/10/2012, 10:39

... Expression of SV40 T antigen in promoter-reporter assays yielded deregulation, which was dependent on the CDE of the human Cdc25C promoter. Dimethyl sulfate footprint- ing of the CDE in the presence of ... footprinting. Loss of the two pocket proteins leads to deregulation of the B-Myb promoter during the cell cycle. Re-intro- duction of p107, and to some extent also p130, cause...

Ngày tải lên: 16/02/2014, 09:20

... indicate that poly- merization of Gag occurs mainly through the forma- tion of an intermediate layer of cup-shaped structures, each made of one hollow hexameric ring of CA domains placed immediately ... pseudoatomic models of capsid-like particles [30,39]; (b) analyses of the effect of CA mutations on the assembly of mature capsid- like particles (Fig. 2E,F) and ⁄ or the for...

Ngày tải lên: 18/02/2014, 06:20

... mature capsid of human immunodeficiency virus, HIV-1, is formed by the assembly of copies of a capsid protein (CA). The C-terminal domain of CA, CTD, is able to homodimerize and most of the dimerization ... shifts of the whole dimer- ization helix of CTD [27] (otherwise, those chemical shifts are too broad to be observed because of the presence of interconverting conformers)...

Ngày tải lên: 18/02/2014, 06:20

... biological function of the pro-form of bone morphogenetic protein-2 (BMP-2), a member of the transforming growth factor b (TGFb) ⁄ BLP superfamily. The role of the 263 amino acids of the pro-peptide ... experi- ments demonstrate binding of proBMP-2 to the ECD of BMPR-IA. Interaction of BMP-2 (A) and proBMP-2 (B) with immobilized ECD of BMPR-IA. Interaction of BMP-2 (C) and...

Ngày tải lên: 18/02/2014, 06:20

... understanding of the ACMSD catalytic mechanism is still incomplete. In light of the reported ACMSD upregulation in the liver of streptozotocin-induced diabetic rats and the suppres- sion of such elevation ... with Arg47 (distance of 3.0 A ˚ ), an electrostatic interaction with the Zn 2+ ion (closest distance of 4.1 A ˚ ) and an extensive network of hydrogen bonds involving a set...

Ngày tải lên: 18/02/2014, 06:20

... 100 lm of (GlcNAc) 1–4 was analysed at the start, in the middle and at the end of each series of sam- ples. The resulting average values of the standards (display- ing standard deviations of < ... 4MU-(GlcNAc) 2 as substrate; 50 lL of supernatant was mixed with 50 lLof 50 mm citrate–phosphate buffer, pH 3.8, containing 50 lm of substrate and 0.1 mgÆmL )1 of bovine serum alb...

Ngày tải lên: 18/02/2014, 08:20

... presence of SDS, and of random coil values for a protein of the same sequence. Fig. S2. In-cell NMR. 1 H- 15 N HSQC spectra of the E. coli slurry [(A), not induced; (B), induced and of the supernatant ... spectra of J1_ic (7.0 lm) in buffer alone and in the presence of SDS (3 mm) at pH 7.4 and at pH 6. Fig. S8. CD of J1_ic. Far-UV CD spectra of J1_ic (7.0 lm) in buffer alone...

Ngày tải lên: 18/02/2014, 16:20

... stability of HPr of S. coelicolor (Eur. J. Biochem. 271) 2177 Validation of the LEM in analysis of scHPr data The use of LEM in several proteins has resulted in the complete determination of the ... understanding of the physical interactions underlying the structure, folding and the function of a protein requires a detailed description of its conformational stability in term...

Ngày tải lên: 19/02/2014, 12:20