Báo cáo khoa học: "CONTEXT-FREENESS AND THE COMPUTER PROCESSING OF HUMAN LANGUAGES" pot
... i d, and it is left to the bookkeeping phase of the compiler to keep track of declarations and uses of particular names. The bookkeeping has Co be done, of course, even in the case of languages ... generative capacity, and time complexity of recognition. All three of these matters should be of concern to theoretical linguists; the study of what mathematic...
Ngày tải lên: 24/03/2014, 01:21
... 2011 Stability and fibril formation properties of human and fish transthyretin, and of the Escherichia coli transthyretin-related protein Erik Lundberg 1 , Anders Olofsson 2 , Gunilla T. Westermark 3 and ... polar residues, Thr75 and His88 (hTTR number- ing), buried within the hydrophobic core of the mono- mers. The side chains of these residues form, together with...
Ngày tải lên: 16/03/2014, 01:20
... terminal in the sinus gland, as a result of late and progressive isomerization of the Phe3 of the CHH during the migration of the secretion vesicles along the axonal tract [39,41]. The immunohistochemical ... microscopy study of the neuronal endings in the sinus gland to determine the subcellular localization of the different epimers. Taken together, these...
Ngày tải lên: 18/02/2014, 11:20
Tài liệu Báo cáo khoa học: Structural and functional specificities of PDGF-C and PDGF-D, the novel members of the platelet-derived growth factors family docx
... cell infiltrates of the lung and fibro- sis in the liver [110]. Conclusions The novel members, PDGF-C and -D, of the PDGF subfamily of the cystine knot family of growth factors are potent cytokines ... removal of the CUB domains and thereby activation of the growth factor domains. PDGF-C and -D contain both the CUB and growth factor domains when they are se...
Ngày tải lên: 19/02/2014, 07:20
Tài liệu Báo cáo khoa học: nsights into the reaction mechanism of glycosyl hydrolase family 49 Site-directed mutagenesis and substrate preference of isopullulanase doc
... IPU consists of a signal sequence (residues 1–19) and a mature part (residues 20–564), and the model is composed of residues 25–540. The overall structure of the model of IPU and the mutated residues ... polysaccharide, pullulan. Comparison of the active sites of the model of IPU and Dex49A The active site structures of t he model of IPU (Fig. 4A) and...
Ngày tải lên: 19/02/2014, 16:20
Báo cáo khoa học: NMR and molecular dynamics studies of an autoimmune myelin basic protein peptide and its antagonist Structural implications for the MHC II (I-Au)–peptide complex from docking calculations ppt
... elucidate the role of the positively charged residue Arg78 and the effect of the reduction of cationicity of MBP in the triggering of multiple sclerosis. Flexible docking calculatio ns of the MBP(74–85) epitope ... ey characteristic of the structure of the native epitope in Me 2 SO is the presence of a large number of electrostatic interactions, especia...
Ngày tải lên: 07/03/2014, 16:20
Báo cáo khoa học: Covalent and three-dimensional structure of the cyclodextrinase from Flavobacterium sp. no. 92 pdf
... between the long B-domain extension of CDase (His251, Fig. 7) and the N-terminal domain of the other subunit of the TVA-II dimer (Tyr45¢). It has been suggested that the N-terminal domain of the ... the loops at the opposite barrel end. The lengths of the b-strands in the barrel vary from two (b14) to seven (b11) residues. As in other enzymes of family no....
Ngày tải lên: 08/03/2014, 02:20
Báo cáo khoa học: MicroRNAs and the regulation of fibrosis potx
... within the 3¢-UTR of target genes. The specificity of the miRNA guide strand is thought to be mediated by the ‘seed’ region localized between resi- dues 2 and 8 at the 5¢ end [5–7], and the specificity ... organs including the heart, kidney, liver and lung. In this review, we summarize our current understanding of the role of miRNAs in the development of tissue...
Ngày tải lên: 15/03/2014, 11:20
Báo cáo khoa học: High and complementary expression patterns of alcohol and aldehyde dehydrogenases in the gastrointestinal tract Implications for Parkinson’s disease docx
... observed in the epithelial cells of the tongue and esophagus, in the gastric glands and at the base of the villi in jejunum. The apparent signal in the outer keratinized layer of the tongue and esophagus ... epithelial cells at the base of the villi. In colon, Aldh1 gene activity was detected in the upper parts of the crypts of Lieberku ¨ hn, whereas...
Ngày tải lên: 16/03/2014, 11:20
Báo cáo khoa học: Principles behind the multifarious control of signal transduction ERK phosphorylation and kinase/phosphatase control potx
... how the second kinase in the cascade determines the time dependence of the activity of the third kinase, we varied the V max of the second kinase reaction and recalculated the concentration of the ... controlled by the kinases or phosphatases in the system, and whether they are controlled differ- entially by some or all of them. On the basis of the an...
Ngày tải lên: 16/03/2014, 18:20