Báo cáo Y học: Interactions between the Fyn SH3-domain and adaptor protein Cbp/PAG derived ligands, effects on kinase activity and affinity docx
Báo cáo Y học: Interactions between the Fyn SH3-domain and adaptor protein Cbp/PAG derived ligands, effects on kinase activity and affinity docx
... Authors Journal compilation ª 2008 FEBS Interactions between the Fyn SH3-domain and adaptor protein Cbp/PAG derived ligands, effects on kinase activity and affinity Silje A. Solheim 1,2 , Evangelia ... substrates. Results and Discussion Phosphorylation of the adaptor protein PAG is depen- dent on an initial interaction between the first proline- r...
Ngày tải lên: 24/03/2014, 00:21
Báo cáo Y học: Inhibition of the SERCA Ca21 pumps by curcumin Curcumin putatively stabilizes the interaction between the nucleotide-binding and phosphorylation domains in the absence of ATP pot
... sites and ligands, respectively, and [EL] is the concentration of bound ligand. The total concentration of sites can be expressed as N[E] 0 , the product of total protein concentration ([E] 0 ) and the ... the activity of a number of key enzymes such as cyclooxygenase [9], protein kinase C [10], protein tyrosine kinases [11] and a Ca 2þ -dependent endonuclease [1...
Ngày tải lên: 08/03/2014, 23:20
Báo cáo y học: "Use of the measure your medical outcome profile (MYMOP2) and W-BQ12 (Well-Being) outcomes measures to evaluate chiropractic treatment: an observational study"
... two symptoms (physical or mental) which bother you the most. Write them on the lines. Now consider how bad each symptom is, over the last week, and score it by circling your chosen number. SYMPTOM ... This may have had some impact on the observed findings as well as influencing the external validity of the study. Conclusions This study assesses the use of the MYMOP2 a...
Ngày tải lên: 25/10/2012, 10:06
Báo cáo y học: "Impact of the Kenya post-election crisis on clinic attendance and medication adherence for HIV-infected children in western Kenya"
... them to go on the roads and try to get [to clinic]. The risks to personal safety were seen to vary based on the fam- ilies' tribal affiliation, their location, and whether they were in the ... There was one boy who was being taken care of by the uncle. They stay in Langas. Langas was, let me say, it was the heat of the violence there. This boy is on second line me...
Ngày tải lên: 25/10/2012, 10:31
Báo cáo y học: "Evaluation of the Prevalence of Concomitant Idiopathic Cyclic Edema and Cellulit"
... in regional lymphostasis in the skin which impedes the mobilization of these substances leading to their accumulation. Among the factors that affect this system are female hormones and genetic ... based on the clinical severity. Grade I is characterized by smooth skin without any dimpling upon standing and laying down, but the skin adopts a mattress-like (orange peel) co...
Ngày tải lên: 25/10/2012, 10:51
Báo cáo y học: "Enhancement of the Click Chemistry for the Inverse Diels Alder Technology by Functionalization of Amide-Based Monomers"
... restricting the ligation efficiency. The ligation starts with the chemical reaction of the Reppe Anhydride derivative monomer 3, the reaction partner with the higher reactivity. After completion, the ... second ligation reaction with the pentenoic acid 2 begins. The process of the chemical reaction can be monitored by the colour change and the end of the react...
Ngày tải lên: 25/10/2012, 11:00
Báo cáo y học: "Relationship between Anti-CCP Antibodies and Oxidant and Anti-Oxidant Activity in Patients with Rheumatoid Arthrit"
... Fethi Ceylan 3 1. Yuzuncu Yil University, Medical Faculty, Department of Physical Medicine Rehabilitation and Rheumatology, Van, Turkey; 2. Yuzuncu Yil University, Medical Faculty, Department ... phosphory- lation and repetitive cycles of hypoxia and reoxygen- ation, along with oxidants produced by phagocytic cells such as macrophages and neutrophils, lead to chronic oxidative...
Ngày tải lên: 25/10/2012, 11:15
Báo cáo y học: " Efficacy of the Valsalva Maneuver on Needle Projection Pain and Hemodynamic Responses During Spinal Puncture"
... orally on the morning of surgery. On arrival in the operating room, ECG electrodes and non-invasive blood pressure (NIBP) monitor were applied and oxygen saturation was monitored by pulse oxymeter. ... effi- cacy of balloon inflation on venipuncture pain in pe- diatric and adult patients. In a study by Gupta et al on seventy-five pediat- ric patients aged 6–12 yr, the...
Ngày tải lên: 25/10/2012, 11:15
Báo cáo y học: "Extension of the PNA world by functionalized PNA monomers eligible candidates for inverse Diels Alder Click Chemistyr"
... of the PNA back- bone monomer using the fluorenylmethoxycarbonyl (Fmoc) protection occurred as described by Atherton and Sheppard.[40] Synthesis of the Fmoc-C2-glycine-tert-butyl ester The ... stirring constantly. In the process the reaction solutions colour changes to yellowish. The reaction batch was stirred continuously over night and concentrated by the rotary eva...
Ngày tải lên: 26/10/2012, 08:57
Báo cáo y học: " Factors affecting the long-term response to tacrolimus in renal transplant patients: Pharmacokinetic and pharmacogenetic approac"
... is mainly metabolized by CYP3A4 and CYP3A5 enzyme isotype. CYP3A5 polymorphisms seem to affect tacrolimus kinetics at a greater degree com- pared to CYP3A4 ones and thereby, these polymor- phisms ... transporters and the metabolizing en- zymes [7,9]. CYP3A, the primary subfamily of the cytoch- rome P450 (CYP) enzymatic system, is responsible for the metabolism of tacrolimus...
Ngày tải lên: 26/10/2012, 09:32