Báo cáo Y học: Progestin upregulates G-protein-coupled receptor 30 in breast cancer cells pot
Báo cáo Y học: Progestin upregulates G-protein-coupled receptor 30 in breast cancer cells pot
... transmembrane G-protein-coupled receptor 30 (GPR30) is expressed preferentially in estrogen receptor- positive breast cancer cells as well as in endocrine tissues [12–14]. Some G-protein-coupled receptors ... lines [3–5], progestins inhibit estrogen- stimulated cell proliferation. The mechanism of progestin- induced growth is mostly unknown. Progestin regulates many cel...
Ngày tải lên: 24/03/2014, 00:21
Báo cáo Y học: Regulation of a1,3galactosyltransferase expression in pig endothelial cells Implications for xenotransplantation doc
... using the Prime-a-gene labeling system (Promega). Double-positive clones were purified by secondary and tertiary r ounds of screening and genomic DNA inserts were purified using poly(ethylene glycol) ... promoter is independent of TATA-binding-protein-associated factors and initiator-binding proteins. Mol. Cell Biol. 17, 2973–2984. 32. Weis, L. & Reinberg, D. (1992) Transcription by RNA pol...
Ngày tải lên: 08/03/2014, 16:20
Báo cáo khoa học: Towards discovery-driven translational research in breast cancer pdf
... 40 years, and breast cancer is now the number one cause of can- cer mortality in women. Today, routine mammography, i.e. screening for breast cancer by X-ray examination, is the only accep- ted ... profiling of the cancer microenvironment by antibody arrays. Proteomics 1, 1271–1278. 72 Hinsby AM, Olsen JV & Mann M (2004) Tyrosine phosphoproteomics of FGF signaling – a role for...
Ngày tải lên: 30/03/2014, 15:20
Báo cáo Y học: Probing intermolecular protein–protein interactions in the calcium-sensing receptor homodimer using bioluminescence resonance energy transfer (BRET) potx
... Ala 116 -Pro 136 region in the calcium-sensing receptor. Constitutive activity and inverse agonism in a family C G-protein-coupled receptor. J. Biol. Chem. 275, 29547–29555. 52. Chen, R., Mukhin, Y. V., Garnovskaya, ... Michnick, S.W. (1999) Erythropoietin receptor activation by a ligand-induced conformation change. Science 283, 990–993. 33. Schlessinger, J. (2000) Cell signaling b...
Ngày tải lên: 08/03/2014, 09:20
Báo cáo y học: "Pre-hospital intubation by anaesthesiologists in patients with severe trauma: an audit of a Norwegian helicopter emergency medical service"
... severity of injury or illness index (NACA) [16] Score Definition 0 No injury or disease 1 Injuries/diseases without any need for acute physician care 2 Injuries/diseases requiring examination ... not intubated. Another recent study also indicated that delaying ALS in critically injured patients until arrival in the trauma centre worsens outcome [21]. One remaining question in this study...
Ngày tải lên: 25/10/2012, 09:56
Báo cáo y học: "An unusual case of gout in the wrist: the importance of monitoring medication dosage and interaction. A case report"
... Radiographs during early attacks may only reveal soft-tissue swelling. Serum uric acid levels may be normal during an attack due to pro-inflammatory cytokines [5]. The majority of untreated patients ... more common in men. Most acute gouty attacks occur in a single joint in the lower limb with the first metatarsal joint most commonly affected [2,5]. On clinical presentation, the joint o...
Ngày tải lên: 25/10/2012, 10:06
Báo cáo y học: " Introduction of Medical Emergency Teams in Australia and New Zealand: a multi-centre study"
... recording information on critical care resources, including the timing of introduction of METs. In addition, ANZICS maintains an Adult Patient Data- base (ANZICS-APD), which currently contains information ... participated in the MERIT study by comparing the first year of data submission to the second. Finally, in an addi- tional sensitivity assessment, we extended our analysis to hos- p...
Ngày tải lên: 25/10/2012, 10:35
Báo cáo y học: "Utility of routine chest radiographs in a medical–surgical intensive care unit: a quality assurance survey"
... routine CXR [3]. Of 538 routine CXRs, 8% presented new ‘major’ findings; however, 58% of these were anticipated by the clinical examination, and only 3.4% of all routine CXRs presented findings ... any resulting changes in management. The ICU team, consisting of the attending physician, a clinical fellow, and a group of housestaff, interpreted the daily CXRs. CXRs were defined as routine .....
Ngày tải lên: 25/10/2012, 10:45
Báo cáo y học: "2009 H1N1 Influenza and Experience in Three Critical Care Unit"
... antibiotic. Commonly used antibiotics in- cluded moxifloxacin (in 19 patients), linezolid (in 14 patients), ampicilline-sulbactam (in 13 patients), clar- ithromycin (in 13 patients), piperacillin-tazobactam ... piperacillin-tazobactam (in 12 patients), imipenem (in 11 patients), third gen- eration cephalosporin (in 9 patients), vancomycin (in 2 patients), teicoplanin (in 4 pati...
Ngày tải lên: 25/10/2012, 11:04
Báo cáo y học: "ntravenous transplantation of allogeneic bone marrow mesenchymal stem cells and its directional migration to the necrotic femoral head"
... successfully labeled with GFP at 72 h after labeling. MSCs were uniformly distributed in multiple organs and tissues including brain, lungs, heart, kidneys, intestine and bilateral hip joints of ... system and adenovirus vector carrying GFP (Adeasy GFP) were used. The adenovirus vector car- rying GFP was kindly provided by Professor Zhou (Peking University, China). Experimental animals...
Ngày tải lên: 25/10/2012, 11:18