Báo cáo Y học: DAP kinase activity is critical for C2-ceramide-induced apoptosis in PC12 cells ppt
Báo cáo Y học: DAP kinase activity is critical for C2-ceramide-induced apoptosis in PC12 cells ppt
... involved in ceramide-
induced apoptosis, and that the intrinsic DAP kinase activity
is critical for ceramide-induced apoptosis.
Keywords: apoptosis; DAP kinase; ceramide; PC12; CaM
kinase.
Using a ... u@phy.med.kyoto-u.ac.jp
Abbreviations: DAP kinase, death-associated protein kinase; MLC
kinase, myosin light chain protein kinase; CaM kinase, Ca
2+
/cal-
modulin-...
Báo cáo y học: "Proteomic analysis of mechanisms of hypoxia-induced apoptosis in trophoblastic cells"
... characterized by dimin-
ished syncytial differentiation, syncytial knots, and
prominent cytotrophoblasts [1]. Hypoxia is known to
induce apoptosis in various cells, including tro-
phoblastic cells [2-4]. ... proteins induced
by hypoxia in trophoblastic cells so as to clarify the mechanism of hypoxia-induced apoptosis by using the
PoweBlot, an antibody-based Western array. H...
Báo cáo khoa học: Signal peptide hydrophobicity is critical for early stages in protein export by Bacillus subtilis ppt
... inaccessible to trypsin. The latter
pre-AmyQ molecules were only degraded by trypsin in
the presence of Triton X-100, indicating that they were
protected against trypsin activity by the cytoplasmic
membrane. ... Cross-linking of in vitro
synthesized ribosome nascent chain complexes (RNCs) to cytoplasmic pro-
teins showed that signal peptide hydrophobicity is a critical determinant...
Báo cáo Y học: Identification of residues critical for activity of the wound-induced leucine aminopeptidase (LAP-A) of tomato pptx
... its
carboxylate oxygen, C
a
of Asp a nd its carboxylate oxygen,
C
a
of Arg and its side-chain amines or guanidinium, and C
a
of Lys and its side-chain amine was determined by
measuring distances in ... wild-type His
6
–LAP-A activity
(± standard d eviation). T he hydrolysis rates for the wild-typ e H is
6
–LAP-A are shown in lmolÆmin
)1
Æmg protein
)1
. Rates indicated as < 0.5%...
Báo cáo khoa học: The F13 residue is critical for interaction among the coat protein subunits of papaya mosaic virus doc
... Imidazole was eliminated by dialysis for
24 h. Protein purity was determined by SDS/PAGE and
confirmed by western immunoblot analysis using rabbit
polyclonal antibodies generated against purified PapMV
virus.
Separation ... assemble, form disks or interact with RNA in vitro
[10]. On the basis of this result, we hypothesized that
the N-terminus of the CP is involved in contact among
NLP...
Báo cáo khóa học: ICAM-1 expression is highly NF-jB-dependent in A549 cells No role for ERK and p38 MAPK docx
... potential
utility of inhibiting the NF-jB signalling pathway in
pulmonary in ammatory diseases and suggest that inhibi-
tors of the p38 and ERK MAPK pathways may be of lesser
effect in this cell type.
Acknowledgements
N. ... demonstration in pulmon-
ary epithelial cells is currently lacking. As NF-jBis
considered to be a candidate for therapeutic intervention
in airway in amma...
Báo cáo khoa học: "A Class-Based Agreement Model for Generating Accurately Inflected Translations" pptx
... The inputs are a translation
hypothesis
e
I
1
, an index
n
distinguishing the prefix
from the attachment, and a flag indicating if their
concatenation is a goal hypothesis.
The beam search maintains ... model:
Input: implicitly defined search space
generate initial hypotheses and add to H
set H
f inal
to ∅
while H is not empty:
set H
ext
to ∅
for each hypothesis η in H:
if η is a goal...
Tài liệu Báo cáo Y học: Ornithine decarboxylase-antizyme is rapidly degraded through a mechanism that requires functional ubiquitin-dependent proteolytic activity pot
... unresolved
mechanism [17,18]. Mammalian cells contain another
relevant regulatory protein, antizyme inhibitor, a protein
that displays homology t o ODC, but lacks d ecarb oxylating
activity [19]. It binds ... supported
mainly by the experiment like that presented in Fig. 2A as in
653 cells antizyme is present in vast excess whereas ODC is
practically undetected. Testing for...
Báo cáo Y học: ik3-1/Cables is a substrate for cyclin-dependent kinase 3 (cdk 3) pdf
... is regulated by G1 cyclin
and cyclin-dependent kinases (cdks). Cdk4 or cdk6 is
associated with D-type cyclins while cdk2 binds to cyclin E
or cyclin A to become an independent and essential kinase
[1,2]. ... previously [15].
RESULTS
P70
ik3-1
is phosphorylated by cyclin A/cdk2, cyclin E/cdk2,
cyclin A/cdk3 or cyclin E/cdk3 which is produced in the
baculoviral system
We initially t...
Báo cáo y học: "Elevated plasma homocysteine is positively associated with age independent of C677T mutation of the methylenetetrahydrofolate reductase gene in selected Egyptian subjects"
... played by cytokines in the evolution of
insulin resistance. Could hyperhomocysateineamia be a result of derangement of certain cytokine
production?
Abbreviations
tHcy: total homocysteine; ... disease, primary renal disease or any collagenic diseases.
All subjects gave informed consent before the study began. Patients who had history of myocardial
infarction (confirmed by ECG findings...