Novel technique for rapid detection of a-globin gene mutations and deletions pot

... Novel technique for rapid detection of a-globin gene mutations and deletions JINGZHONG LIU, XINGYUAN JIA, NING TANG, XU ZHANG, XIAOYI ... frequencies of a-thalassemia caused by a-globin gene mutations and deletions. This study was designed to find an efficient and simple diag- nostic test for the mutations and deletions. Translational Significance A ......

Ngày tải lên: 23/03/2014, 22:20

... al. Systematic review of the effectiveness and cost-effectiveness, and economic evaluation, of myocardial perfusion scintigraphy for the diagnosis and management of angina and myocardial infarction. ... USA alone the p revalence of CAD is estimated at 5.9% of all Cauca- sians of age 18 and older [3]. Accurate, n on-invasive diagnosis of, and screening for, CAD...

Ngày tải lên: 03/11/2012, 10:58

... YG3003 and/ or YG7108 strain, and 21 chemicals (8.2%) formed 8-OH-Gua in the rat hepatocytes oxidized DNA. These results may demonstrate the utility and limitation of both the Ames test and 8-OH-Gua ... 8-OH-Gua Introduction Genotoxicity of carcinogens is considered one of the most important contributors to cancer and a marker of the cancer risk of various populations. Ther...

Ngày tải lên: 05/09/2013, 08:40

... document potential areas of loss of autofluorescence that might be indicative of cyto- logic and/ or molecular changes indicative of premalignan- cy. Nineteen of 20 tumors demonstrated loss of autofluorescence ... shown to have sensitivity and specificity rates of 93 and 98%. 15,16 One explanation for this discrepancy is that early lesions of oral cancer and precancer ar...

Ngày tải lên: 06/03/2014, 02:21

... °C and leave for several minutes (approximately 5 min). Add 0,25 ml of the reagent for detection of β -galactosidase and mix. Replace the tube in the water bath set at 37 °C and leave for ... portion and initial suspension 9.1.1 General See ISO 6887-1 and the specific International Standard dealing with the product concerned. See ISO 8261 for milk and milk produ...

Ngày tải lên: 07/03/2014, 16:20

... values (TLV) for NO 2 and NO are 3 and 25 ppm, respectively [5]. Therefore, a NO x sensor requires high sensitivity for detecting low concentration of gases. Another enormous driving force for developing ... to monitor the concentration of NO and NO 2 gases because of the low concentration, one of the roles of the Ag is apparent to provide surface for the conversion o...

Ngày tải lên: 19/03/2014, 16:47

... SELDI-TOF-MS to identify candidate markers for endometrial cancer [62]. Two of the candidates turned out to be apolipoprotein A-1 and apolipoprotein C-1. Dual-biomarker analysis for the detection ... resulting from the lack of reliable, sensitive screening tests and our limited understanding of the mechanisms of chemoresistance and relapse. More than two-thirds of ca...

Ngày tải lên: 22/03/2014, 11:20

... the Center of Excellence in Connective Tissue (to A.S. and J.Z.) and Center of Excellence in Genomics and Bioinformatics (to A.S.), UTHSC, and NIH grants 1R01-AR047079-0 1A2 (to A.S.) and RR017854. ... thank Professor Cedric Shackelton, Children’s Hospital Oakland Research Institute, Oakland, CA, USA for performing G C/MS an alyses, and Pr ofessor Walter Miller, U niversity...

Ngày tải lên: 23/03/2014, 13:20

... BUILDING(s) (of) ONE/ALONE (of) DOUBLE/GEMINATE (of) ANNUAL/YEARS (of) LAYER/LAMELLA (of) (to /for) (by/with/as) LINE (of) THIN-CRUST(s) HOW/AS/BUT (of) (to /for) (by/with/as) FOSSILIZED (of) (to /for) - ... sults of applying the technique to a set of twenty one Russian sentences indicate that the technique can be successful in about 90% of the cases. The technique can e...

Ngày tải lên: 30/03/2014, 17:20

... nanotubes. On the other hand, the formation of the nanotubes using conventional magnetic stirring is retarded by the formation of a double layer and diffusion-limited transport of the species. A better ... pit formation continuing until repassivation oc- curs [17,19]. Nanotube formation goes through the diffusion of F − ions and simultaneous effusion of the [TiF 6 ] 2− ions. The...

Ngày tải lên: 05/05/2014, 15:26