Báo cáo Y học: Stepwise adaptations of citrate synthase to survival at life’s extremes From psychrophile to hyperthermophile pot
Báo cáo Y học: Stepwise adaptations of citrate synthase to survival at life’s extremes From psychrophile to hyperthermophile pot
... et al. (Eur. J. Biochem. 269) Ó FEBS 2002 Stepwise adaptations of citrate synthase to survival at life’s extremes From psychrophile to hyperthermophile Graeme S. Bell 1 , Rupert J. M. Russell 2 , ... structures of citrate synthase from differ- ent organisms to a total of five that span the temperature range over which life exists (from psychrophile to...
Ngày tải lên: 23/03/2014, 21:20
Báo cáo y học: "ntravenous transplantation of allogeneic bone marrow mesenchymal stem cells and its directional migration to the necrotic femoral head"
... Department of Orthopedics, Affiliated Hospital of Hebei University, Baoding 071000, China. 3. Laboratory of Biochemistry and Molecular Biology, Institute of Basic Medical Sciences, Academy of Military ... intravenously injected into nude mice and the distribution and mi- gration of MSCs were dynamically monitored to evaluate the feasibility and safety of intravenous im- pla...
Ngày tải lên: 25/10/2012, 11:18
Tài liệu Báo cáo Y học: Functional analysis of DM64, an antimyotoxic protein with immunoglobulin-like structure from Didelphis marsupialis serum pdf
... speculate that DM64 binds to the myotoxins through a myotoxic/ cytolytic site distinct from the catalytic site, as already described for the inhibition of myotoxicity by heparin [44]. At least ... 6057 catalytically active PLA 2 , the membrane disorganization seems to be potentiated by enzymatic degradation of phospholipids [7,44]. The capacity of DM64 to inhibit the myotoxici...
Ngày tải lên: 21/02/2014, 01:21
Tài liệu Báo cáo Y học: Divergent members of a soybean (Glycine max L.) 4-coumarate:coenzyme A ligase gene family potx
... basically occur by different pathways, namely by modifications at the free acid level, by s ubstitutions at the level of conjugated intermedi- ates, such as CoA esters, and at the level of the aldehyde ... and the dynamics of their synthesis. In any case, the coordinated r egulation of 4 CL3 or 4 with a ll other known enzymes of phytoalexin biosyn- thesis in soybean [24] indic...
Ngày tải lên: 22/02/2014, 04:20
Báo cáo Y học: Differential regulation of the Fe-hydrogenase during anaerobic adaptation in the green alga Chlamydomonas reinhardtii pot
... sequence of the mature HydA polypeptide from C. reinhardtii shows 60% identity and 71% similarity to the Fe-hydrogenase o f S. obliquus [27], which was recently isolated on the basis of the data of ... enzyme. The amino-acid sequence of HydA shows only c onsiderable similarity to Fe-hydro- genases but not to NiFe-hydrogenases. The Fe-hydrogenase family is one c lass of hydro...
Ngày tải lên: 08/03/2014, 22:20
Báo cáo Y học: Heterologous expression of a Rauvolfia cDNA encoding strictosidine glucosidase, a biosynthetic key to over 2000 monoterpenoid indole alkaloids pot
... by condensation of tryptamine, the decarboxylation product of tryptophan, and the monoter- pene secologanin catalysed by the enzyme strictosidine synthase (SS) [11]. The biosynthetic pathways ... relative conversion rate of 90%. Changing the structure of strictosidine by acetylation of the b nitrogen leads to more significant decrease of conversion than methylation of the b n...
Ngày tải lên: 24/03/2014, 03:21
Báo cáo Y học: Identification of a critical lysine residue at the active site in glyceraldehyde-3-phosphate dehydrogenase of Ehrlich ascites carcinoma cell ppt
... catalyzed by phosphoglycerate kinase and the 1,3-bisphosphoglycerate formed was reduced by NADH to GraP by Gra3P DH; the oxidation of NADH was monitored at 340 nm [10]. One unit of activity of ... enzyme of the glycolytic pathway, may play a primary role in the high aerobic glycolysis of malignant cells [2 –11]. These investigations have indicated a strong enhancement of expre...
Ngày tải lên: 24/03/2014, 04:21
Báo cáo khoa học: Weak oligomerization of low-molecular-weight protein tyrosine phosphatase is conserved from mammals to bacteria pot
... Thus, although phosphorylation and dimerization could be related regulatory events in most lmwPTPs, phosphorylation cannot be a regu- latory mechanism of YwlE. However, dimerization, as shown below, ... regulation of lmwPTPs is not completely understood and different mechanisms have been described [6]. Reversible inactivation by oxidation of the catalytic cysteine of phosphatases has...
Ngày tải lên: 16/03/2014, 02:20
Báo cáo Y học: A nonphosphorylated 14-3-3 binding motif on exoenzyme S that is functional in vivo pot
... capacity to ADP ribosylate cytoplasmic proteins, e.g. Ras, and shows a reduced capacity to change the morphology of infected cells. Keywords: ADP-ribosylation; coenzyme binding site; cyto- toxicity; ... – namely the small G-protein Ras – as a readout [35]. Secondly, we employed a cytotoxicity assay, since the ADP- ribosylation activity of ExoS mediates a marked change in cell morpholo...
Ngày tải lên: 31/03/2014, 08:20
Báo cáo y học: "The epidemiology of medical emergency contacts outside hospitals in Norway - a prospective population based study"
... cardiovascular symptoms K29 (68) Loss of consciousness 945 19 4.6 21 200 Syncope/coma A06/07 (945) Respiratory 472 10 2.3 10 600 Dyspnoea/breathing problems R02/04 (430) Other respiratory symptoms R29 ... pain related to the heart dominated the cardiovascular patients with 95%. Of the 465 patients categorised under “Other”,23% had a problem related to pregnancy or labour. Most of th...
Ngày tải lên: 25/10/2012, 09:56