... Thus, although phosphorylationand dimerization could be related regulatory eventsin most lmwPTPs, phosphorylation cannot be a regu-latory mechanism of YwlE. However, dimerization,as shown below, ... regulation of lmwPTPs is not completelyunderstood and different mechanisms have beendescribed [6]. Reversible inactivation by oxidation of the catalytic cysteine of phosphatases has been shown to ... dimeriza-tion site of YwlE, replacing a tyrosine residue conserved in all eukaryoticlmwPTPs, demonstrates that lmwPTP regulation by oligomerization can beindependent from tyrosine phosphorylation.Structured...