Báo cáo Y học: Structural and compositional changes in very low density lipoprotein triacylglycerols during basal lipolysis potx

... Ontario, Canada Triacylglycerols secreted by liver and carried by very low density lipoprotein (VLDL) are hydrolysed in circulation by lipoprotein and hepatic lipases. These enzymes have been shown ... compositional changes in very low density lipoprotein triacylglycerols during basal lipolysis Jyrki J. A ˚ gren 1,2 , Amir Ravandi 1 , Arnis Kuksis 1 an...

Ngày tải lên: 23/03/2014, 21:20

... full-length proteins. Keywords: calretinin; calcium; calbindin D 28k ; EF-hand; NMR secondary structure. Calretinin (CR) and calbindin D 28k (Calb) are homologous calcium-binding EF-hand proteins with ... conformational changes in calbindin-D 28K (the vitamin D-induced calcium binding protein) interactions with chick intestinal brush border membrane alkaline phosphatase as studied via p...

Ngày tải lên: 22/02/2014, 07:20

... dimerization in helix IV (Figs 3 and 5). The binding of Ca 2+ to calhepatin increases its intrinsic fluorescence intensity and k max . This result, the decrease in the protein hydrodynamic volume, and ... Mg 2+ changes calhepatin fluorescence, suggesting that they have no binding sites in the protein. In addition, they have no effect on Ca 2+ binding (not shown). Calhepatin fluor...

Ngày tải lên: 08/03/2014, 22:20

... Nikolay P. Arbatsky 2 , Alexander S. Shashkov 2 and Yuriy A. Knirel 2 1 Department of General Microbiology, Institute of Microbiology and Immunology, University of èodz  , Poland; 2 N. D. Zelinsky Institute ... strains 1 and 4 were studied using sugar analysis, 1 Hand 13 C NMR spectroscopy, including 2D COSY, H-detected 1 H, 13 CHMQC ,and rotating-frame N OE s pectroscop y ( ROESY)....

Ngày tải lên: 17/03/2014, 17:20

... activity. The AFPs are structurally and evolutionarily diverse but are all functionally similar in that they bind ice and depress the freezing point. They are found in a variety of insect and plant ... trypsin, untreated AFP (UT AFP), and deglycosylated AFP (DG) are id entified. Bands smaller than 1 4 kDa in lan es containing trypsin were shown to b e trypsin autolysis products (...

Ngày tải lên: 24/03/2014, 03:21

... sym- metrical and asymmetrical parallel corpora. In Pro- ceedings of the 23rd International Conference on Computational Linguistics (COLING’10), Beijing, China. Alexandru Ceaus¸u, John Tinsley, ... Multi-task minimum error rate training In contrast to task pooling and task mixtures, the specific setting addressed by multi-task minimum error rate training is one in which the generativ...

Ngày tải lên: 22/02/2014, 03:20

... family with a broad spectrum of substrates including steroids. Preliminary results indicated that these enzymes work by reducing progesterone and 17a-hydroxyprogesterone; mol- ecules having 20-one ... residues are D47, Y5 2, K81 and H114. In relation to the cosubstrate binding site, the amino acids K256, S257, R262 and N266 of DpARs would be involved in NAD(P)H binding. The residue...

Ngày tải lên: 18/03/2014, 01:20

... H-DNA; intramolecular triplex DNA; poly- pyrimidine/ polypurine sequence. There is a wealth of evidence indicating that short pyrimidine/purine-biased (Pyr/Pur) mirror symmetry sequences adopt an intramolecular ... triplex-forming Pyr/Pur regions exist in the genome widely and abundantly, certain Pyr/Pur loci may offer the triplex stems for inter- and intra-chromosomal interactions to m...

Ngày tải lên: 31/03/2014, 23:20

... endotoxin-induced monokine release by human low- and high -density lipoproteins and by apolipoprotein A-I. Infect. Immun. 61, 5140–5146. 5. YuB.,Hailman,E.&Wright,S.D.(1997)Lipopolysaccharide binding ... ÔapolipoproteinsÕ.Theyserve as ligands for cell membrane receptors, as cofactors for enzymes, and can dock lipopolysaccharide-binding pro- teins. They are classified as very- low...

Ngày tải lên: 17/03/2014, 10:20

... an invariantpartofallthreeclassesoftheplantperoxidase superfamily [44]. This motif (shown in grey shading in Fig. 1) includes Ser96 and Asp99 located at the beginning of helix D and connecting to the following long loop in a tight hydrogen bonding network ... disulfide bridges linking HRPC cysteine residues, 11–91, 44–49, 97–301, and 177–209 are conserved in class III peroxidases...

Ngày tải lên: 21/02/2014, 01:21